Protein Alignment CG5122 and CPT1C

DIOPT Version :10

• Sequence 1: NP_609601.1
• Gene: CG5122 / 34703
• FlyBaseID: FBgn0032471
• Length: 1263
• Species: Drosophila melanogaster
• Sequence 2: NP_001365411.1
• Gene: CPT1C / 126129
• HGNCID: 18540
• Length: 825
• Species: Homo sapiens
• Alignment Length: 668
• Identity: 186/668 - (27%)
• Similarity: 305/668 - (45%)
• Gaps: 127/668 - (19%)

  Fly   665 LKKFPALPLKQSIASYLSSIEPFLNEEELKVEQKVAKKFVDNEGAKLQQLLEEEAEGTDNWLTPR 729
            |.:.|...::.::..||.|:.|.|::|:......:|::|:..:.:.||..|..::....|:::..
Human   171 LPRQPVPSVQDTVRKYLESVRPILSDEDFDWTAVLAQEFLRLQASLLQWYLRLKSWWASNYVSDW 235

  Fly   730 WTRSAYLTYQAPLTVFSSPGLSFPIQEFKDTNDFLNFTAK---AIYGMCEFKQLVDQNKIPVVQ- 790
            |....||..:.||.|               .:::....|:   |::.:..::..:::.:||.|:
Human   236 WEEFVYLRSRNPLMV---------------NSNYYMMAARAGNAVHALLLYRHRLNRQEIPPVRG 285

  Fly   791 ---------------------------------MGKHQLDNSQFGKIFGTVRKPGRFCDTIEQYN 822
                                             ||...|.::|:.|||.|.|.||...|.|...:
Human   286 PQWVRDGGVVLWPLGHVGPGRQLTAHGFLQTLLMGMRPLCSAQYEKIFNTTRIPGVQKDYIRHLH 350

  Fly   823 DADYIVVVYNNNYFKLPIYSQSGALLHAHTLRDALQDILE-----CPIKVGKHFGLLTHDNRSNW 882
            |:.::.|.:...:|::..:|:: :||....|....|.||:     ||.:  :|...||...|..|
Human   351 DSQHVAVFHRGRFFRMGTHSRN-SLLSPRALEQQFQRILDDPSPACPHE--EHLAALTAAPRGTW 412

  Fly   883 AEAYTVLCRPHGNADTVETIEQSLFVVCLDNCVPTPKGEER-------IVQAHQLLHGGGVRQNS 940
            |:..|.|  ....|:.:|.:|.:.|.|.||   ..|.|..|       ...||.||.|.|
Human   413 AQVRTSL--KTQAAEALEAVEGAAFFVSLD---AEPAGLTREDPAASLDAYAHALLAGRG----- 467

  Fly   941 ANRWMDKTIQLIVNPNGLAGFCYEHSPADCQPLAMLMDF-VQLKVTEPNYGCEG-CEADKKVTSN 1003
            .:||.||:..|||..||..|...|||.|||.....:.:| :..:..:..|..:| |:.....|..
Human   468 HDRWFDKSFTLIVFSNGKLGLSVEHSWADCPISGHMWEFTLATECFQLGYSTDGHCKGHPDPTLP 532

  Fly  1004 LLKFQP----------VNECINLWLCQARRNIQRIVSQLQMNVINFECYGKCFIKAQGLNPDSYI 1058
                ||          ::..|:|    |.|..:.:...:..:|:.|..:||.||:...|:.||:|
Human   533 ----QPQRLQWDLPDQIHSSISL----ALRGAKILSENVDCHVVPFSLFGKSFIRRCHLSSDSFI 589

  Fly  1059 QMALSLAYYSMYGKIPAQYESAHLRIFHEGRTETIRSTSNESKTFLLAMQSEKASMSEKLAALQK 1123
            |:||.||::...|:....||||..|:|.||||||:||.:.|:..|:.||:.::.:..:.||..:.
Human   590 QIALQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACNFVRAMEDKEKTDPQCLALFRV 654

  Fly  1124 AVDAHEKLIKEAINGQGIDRHLFGLQEMALEKGMPIPEFFRSKGYVRSVTFQLFTSQV------- 1181
            |||.|:.|:|.|::|||:|||||.|  ..:.:.:.:...|.::  |.|..:||.|||:
Human   655 AVDKHQALLKAAMSGQGVDRHLFAL--YIVSRFLHLQSPFLTQ--VHSEQWQLSTSQIPVQQMHL 715

  Fly  1182 ---------ATSNEGFMAYGPLLSDGYGVCY-NPKESKITFAISAWKSCKEINTIRFAKAIKKSL 1236
                     .:|..||   ||....||||.| ...:..|||.||:.||..:.::.|..:.|:.:|
Human   716 FDVHNYPDYVSSGGGF---GPADDHGYGVSYIFMGDGMITFHISSKKSSTKTDSHRLGQHIEDAL 777

  Fly  1237 NDMRKLILLTGGERAGEH 1254
            .|:..|.      :||:|
Human   778 LDVASLF------QAGQH 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5122	NP_609601.1	PTZ00449	<299..668	CDD:185628	1/2 (50%)
		Carn_acyltransf	672..1234	CDD:459926	178/639 (28%)
CPT1C	NP_001365411.1	CPT_N	1..47	CDD:465132
		Carn_acyltransf	174..775	CDD:459926	179/643 (28%)