DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9932 and CG4707

DIOPT Version :9

Sequence 1:	NP_609599.1	Gene:	CG9932 / 34701	FlyBaseID:	FBgn0262160	Length:	2171	Species:	Drosophila melanogaster
Sequence 2:	NP_611944.1	Gene:	CG4707 / 37935	FlyBaseID:	FBgn0035036	Length:	673	Species:	Drosophila melanogaster

Alignment Length:	406	Identity:	86/406 - (21%)
Similarity:	146/406 - (35%)	Gaps:	93/406 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 TSNSTSNTPVAQAGSSL-----LERHVE---RFRLQQLLQQQRQAAAVVAVVNSVQQQQQQQPQQ 99
            :|:|:|.:....:..||     .||:.|   |..::....::|:...|..|..|.::.::::.||
  Fly   254 SSSSSSESSGEDSDHSLPDIEPEERYAEIPKRVVVKPKKYRKREKPLVPPVRLSREEIERRKLQQ 318

  Fly   100 VGMDAKEEGLPQCKIKRNYSCNHCAYFTQNPRYHLTHLRDVHGEKIVINKCKLCLYASRHFQKLV 164
               |..:|.:.|             :|.:.|                   |.||....::|..:.
  Fly   319 ---DEYDEIILQ-------------FFKKFP-------------------CSLCNLLVQNFADMR 348

  Fly   165 RHMKMVHGCTDGIPSGHGQARGKRGMSREARKRRLEESVGVMGGQSLTVTVPDVPTLEQVKRELL 229
            ||.::.|    .|.||:.:..|::...|:|    |.|.|       |....||.....|..|  :
  Fly   349 RHQRVSH----NIESGYIECCGRKFHLRKA----LAEHV-------LVHKNPDHFMCSQCGR--V 396

  Fly   230 LQEEKLQRDIQAFNQRQREEQQREQQRELELVATSAYERQM--QVLRDYERQSPAEPPTPSPTSG 292
            .|:   .|.::...|.....:.:.:.:|..:.......:..  :...:|...|...|.:....|
  Fly   397 FQD---SRALEVHEQTHTNPEVKAEPKEKRIYQCEKCPKSFTTKAAMEYHDVSKHVPKSEFKYS- 457

  Fly   293 SATPPSNGEEPQNRLLK--------------CSACEFTTLYRTQLRAHELAEHG-----KTKFFR 338
              .|..|.:.|..|.||              |..|..|...:|.|:.|...||.     |....:
  Fly   458 --CPECNKKIPTERKLKEHLRYMHDPEAAIICDKCGKTLRSQTNLKKHHELEHSEKPRPKPDPVQ 520

  Fly   339 CDKC-SYVTHIKARFSKHVK-YHSMP--MIKCVTCDFRTPYKWNLDRHM-KNHGGAGAFKCAACD 398
            |:.| :::.|:.. ..:|:| .|..|  ..:|..|:..:.....|.||: .||.....|||..|:
  Fly   521 CEICGTWLRHLSG-LKQHMKTVHEPPGDEHRCHICNKTSTNSRALKRHIYHNHLCERKFKCGMCE 584

  Fly   399 FTADIKQSLTVHEMNH 414
            ......|.|..|...|
  Fly   585 KAFKRPQDLREHTSTH 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9932	NP_609599.1	C2H2 Zn finger	339..359	CDD:275368	5/21 (24%)
		C2H2 Zn finger	366..386	CDD:275368	5/20 (25%)
		C2H2 Zn finger	394..414	CDD:275368	5/19 (26%)
		C2H2 Zn finger	816..836	CDD:275370
		C2H2 Zn finger	844..862	CDD:275370
CG4707	NP_611944.1	zf-AD	3..73	CDD:285071
		C2H2 Zn finger	334..355	CDD:275368	6/20 (30%)
		LIM	<361..407	CDD:295319	13/61 (21%)
		C2H2 Zn finger	365..382	CDD:275368	7/27 (26%)
		C2H2 Zn finger	390..410	CDD:275368	5/24 (21%)
		C2H2 Zn finger	427..443	CDD:275368	0/15 (0%)
		C2H2 Zn finger	458..476	CDD:275368	6/17 (35%)
		C2H2 Zn finger	487..507	CDD:275368	6/19 (32%)
		C2H2 Zn finger	521..540	CDD:275368	4/19 (21%)
		C2H2 Zn finger	551..572	CDD:275368	5/20 (25%)
		C2H2 Zn finger	580..600	CDD:275368	5/19 (26%)
		C2H2 Zn finger	608..629	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444650
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030