DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9932 and CG15073

DIOPT Version :9

Sequence 1:	NP_609599.1	Gene:	CG9932 / 34701	FlyBaseID:	FBgn0262160	Length:	2171	Species:	Drosophila melanogaster
Sequence 2:	NP_611362.2	Gene:	CG15073 / 37155	FlyBaseID:	FBgn0034379	Length:	580	Species:	Drosophila melanogaster

Alignment Length:	420	Identity:	75/420 - (17%)
Similarity:	127/420 - (30%)	Gaps:	151/420 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 CKLCLYASRHFQKLVRHMKMVHGCTD---GIPSGHGQARGKRGMSREARKRRLEE--SVGVMGGQ 209
            |..|......|.:....::..|....   .:.||..|.:.:.|...|.::...:|  .:|:.|.:
  Fly    51 CLTCWNQVNDFHQFYVAVESAHRLLTERFSLKSGQDQGKVEHGEDSEQQEEEQDEDQELGLPGSE 115

  Fly   210 SLTVTVPDVPTLEQVKRELLLQEEK-----------LQRDIQAFNQRQREEQ-QREQQRELELVA 262
            ..:.      |.||...|::.|:|:           ::.|....|..:.... ..||:||....|
  Fly   116 GGSF------TNEQFLTEVIAQQEQQTDSNPPKEQFIKEDNATVNDPETSATLPTEQRRETRSTA 174

  Fly   263 TSAYERQMQVLRDYERQSPAEPPTPS------------PTSGSATPPSN---------------- 299
            .|         :.:....|:.||..|            |.....||..:
  Fly   175 KS---------KAHHSLPPSTPPEKSNSVANKSKAKRTPCKAEGTPQKSKRYADYKQCMLDIDAK 230

  Fly   300 --------------GEE-----------------------------------------PQNRLLK 309
                          |:|                                         |:.  .|
  Fly   231 ISAHMRLTCDVCHEGQETFLLLCKHMLQEHHRKGYAICCNKKFYKRSFLTDHIDRHADPEK--FK 293

  Fly   310 CSACEFTTLYRTQLRAHELAEH--GKTKFFRCDKCSYVTHIKARFSK------HVKYHSMPMIKC 366
            |:.|:.....:..||.|||.:|  .:.|.|.|::|      ..|::|      |...|....:.|
  Fly   294 CTQCDKRFADKQCLRNHELLKHHPEEEKTFMCEQC------PKRYTKQYLLDQHRVIHKERNVVC 352

  Fly   367 VTCDFRTPYKWNLDRHMK-NHGGAGAFKCAACDFTADI---KQSLTVHEMNHHVPPVGNAGSIWP 427
            ..|:.|.|.:..|..|:| .||..|..    ||..|.:   :.:...|::.|       ||...|
  Fly   353 DLCERRFPNQSLLCTHVKMAHGNYGTM----CDICAQVIRGRAAFQRHQLEH-------AGVTEP 406

  Fly   428 RRQNKVGASEMCEDFLSDSAELEDQYNNNN 457
            :.|     .::|..:..:...|:.....:|
  Fly   407 KVQ-----CDICGSWHKNKHSLKKHVRRHN 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9932	NP_609599.1	C2H2 Zn finger	339..359	CDD:275368	5/25 (20%)
		C2H2 Zn finger	366..386	CDD:275368	7/20 (35%)
		C2H2 Zn finger	394..414	CDD:275368	4/22 (18%)
		C2H2 Zn finger	816..836	CDD:275370
		C2H2 Zn finger	844..862	CDD:275370
CG15073	NP_611362.2	zf-AD	2..78	CDD:285071	4/26 (15%)
		C2H2 Zn finger	269..286	CDD:275368	0/16 (0%)
		C2H2 Zn finger	294..316	CDD:275368	7/21 (33%)
		C2H2 Zn finger	325..345	CDD:275368	5/25 (20%)
		C2H2 Zn finger	352..370	CDD:275368	6/17 (35%)
		C2H2 Zn finger	410..430	CDD:275368	2/19 (11%)
		C2H2 Zn finger	437..458	CDD:275368
		C2H2 Zn finger	466..486	CDD:275368
		C2H2 Zn finger	494..512	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100