Protein Alignment CG9934 and ube4b

DIOPT Version :9

• Sequence 1: NP_001162967.1
• Gene: CG9934 / 34699
• FlyBaseID: FBgn0032467
• Length: 1217
• Species: Drosophila melanogaster
• Sequence 2: XP_031762209.1
• Gene: ube4b / 100491174
• XenbaseID: XB-GENE-6037352
• Length: 1331
• Species: Xenopus tropicalis
• Alignment Length: 1367
• Identity: 455/1367 - (33%)
• Similarity: 695/1367 - (50%)
• Gaps: 268/1367 - (19%)

  Fly    71 ELSAEEMRARRLRTLAARSGIQCALAPLTTTPRK---------PT-NVSGESRL-VREATPGEKE 124
            ||||:|:|.|||..||.....| ...|||:..|:         || .||.:..| |:..||
 Frog     3 ELSADEIRRRRLARLAGGPSSQ-PTTPLTSPQRENPPGPPAGAPTPGVSHQLGLNVQGITP---- 62

  Fly   125 VSLPTSAP--AWR--------ELSGKPDMDVEMKSVVSTPMQDVDMTTALSLPTAEATKRSVLQS 179
            .:.||.|.  |.|        .||..|...:|.:|...:..|.:|:.:|       |.::|:.|
 Frog    63 ATSPTGATGVAHRSHSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDSA-------AGEKSMSQ- 119

  Fly   180 CKISAGNAELSI--------------ETVVGPKKSADEQNEQLLSRLLNATWNEYGSGSIICAQS 230
            ..:.:|...:.:              |..:|.:.| :||..||:.::...:|.:.....|.....
 Frog   120 VDVDSGIENMEVDENDRREKRSLPDKEPNLGSEVS-EEQTLQLVCKIFRVSWKDRDRDVIFLQSL 183

  Fly   231 ASFLEQQPHRRF-DFECIVANVLMEAVLKIYNGELIEGDGVSVKADDKEFSSAKKIKSDDTEVQ- 293
            :|...|.|.:.: :::.:::.:|||.::...:.:           ||..|:|........|..|
 Frog   184 SSQFSQNPKKVYSNYKDLISQILMEVLMMSTHSK-----------DDNPFASLTATSQPITVAQI 237

  Fly   294 ---EILANAVA----------TGGATAS------GETAAAAAG-ASG------------------ 320
               .::.|:.:          :|..:||      |.:.|::.. |||
 Frog   238 PNRSLMLNSASKPDTSPMFCNSGSFSASSLSSLYGSSPASSYSLASGIPLCCSPTFPLPNTPQTT 302

  Fly   321 ------------------------------PIEATSSEAAGTCV-----APPVLSI--------- 341
                                          |:...|:..:.|.:     :|.|||.
 Frog   303 VRESVPGSPRLVHSSPSGPRYHPYMMTHSRPLPIPSNLRSSTSLMYVSSSPQVLSSSPRAVLSSS 367

  Fly   342 --------------------------VATTKHHVLLYLIRC------------------------ 356
                                      .:|...|:.|..:.|
 Frog   368 PRQRPTSAANFVAFSPRMSPREIQNPTSTYDSHMSLLSLTCPDEAEGSSDEENHEEEFSCVQFGS 432

  Fly   357 ----------------------YQNYQTEC-------SRKTP--LTQPALQLAFEQVMRMTV--- 387
                                  ..||..||       .||.|  .:||.:......:....:
 Frog   433 SATSSTESCADHFTIETCKETEMLNYLIECFDRVGIEERKAPKMCSQPDVSQLLSNIRLQCICHA 497

  Fly   388 -LVLTDRIYQNLNGHMDQSALLDLMYMAKVSEP--FLIDLIAHTHQDREAFDTIFSQVLRGLFAG 449
             |||...:.|..:  :.|.:|: :.||...:.|  |:.:|:..|:||.|.|..||..:|:||...
 Frog   498 ALVLQGALTQPRS--LQQPSLV-VPYMLCRNLPFGFIQELVRTTYQDEEVFKHIFVPILQGLSQA 559

  Fly   450 MQRNICTSKISVQQIEWLSKLVVIKVGSVRPIADLVSRQPNFLPPICTKISGREIVKCSFLGPFL 514
            .......|......:..|.:|..||.|...|:..|::..|.:||...:..||||:.:.||||.:.
 Frog   560 ATECSLDSDNFKYPLMALGELCEIKFGKTHPVCCLITSLPLWLPKPLSPASGRELQRLSFLGSYF 624

  Fly   515 SVSLFAEENIKFAE-------FTTKNKLEDASSSRLRWELHSMRTNMHVVFHSLCVNASSRPKTL 572
            |:|:|||::.|..|       .|.:|  ....|..|:..|.|.|..:..:.||:.:|..:|...|
 Frog   625 SLSVFAEDDNKVVEKYFSGPAITLEN--TRVVSQSLQHYLESARQELFKIIHSILLNGETREAAL 687

  Fly   573 EYIASILRHNDRRVQFASDEKLLARDGFMINLMSVLQQLSVKIKLDRIEPNFHYYKNSLVNIEQD 637
            .|:|:::..|.::.|..:|::|::.||||:|.:.||||||.||||:.::|.:.::....:.:..|
 Frog   688 NYMAALVNANIKKAQIQTDDRLVSTDGFMLNFLWVLQQLSSKIKLETVDPMYIFHPKCRILLPSD 752

  Fly   638 -TKIRYSEEEYRNF---LARD---FSQPVENTNFQTQCWFLTLQAHHLGYLPAIQRYRQKVRAIK 695
             |:|:.|.||..::   ::.|   ||:|    .|.|:|:||||.||||..||:.:||.:::|||:
 Frog   753 ETRIKASTEEVTSWMSDISNDPSLFSEP----KFPTECFFLTLHAHHLAILPSCRRYIRRLRAIR 813

  Fly   696 ELQKLIDELDRTKSHWMNSRYANRNNQFKERWEKQLRKLNRSKTCCEITLLDPGLLQRCTEFYST 760
            ||.:.::||...:|.|.:|..|.|:.:..:|.:.||:||.|.|.|.:..|||...|:||..||..
 Frog   814 ELNRTVEELKNNESQWKDSPLAARHREMLKRCKTQLKKLVRCKACADTGLLDESFLRRCLNFYGM 878

  Fly   761 VCEFMLYQFEGRPIEGPFIS-KLPVQQLLPTDAFSALPEWYIDDIAEFILFTMQHANMDIRQGID 824
            |.:|:|     |.::..:.: .:|:...:| ..|:.|||:|::|:|||:.|.:|:|...:.:...
 Frog   879 VIQFLL-----RIMDPSYPNITMPLNLDIP-KMFATLPEFYVEDVAEFLFFIVQYAPQVLFEPCT 937

  Fly   825 HSIITWLLTCVCASHLIKNPYVTAKLVEVMFVFSLKPANSVNAAMW-----NHELAQNALVSSLM 884
            ..:.|:|:..:|..:.|:|||:.|||||||||  ..||.......:     :|.|:...||.|||
 Frog   938 QDVATFLVVLLCNQNYIRNPYLVAKLVEVMFV--TNPAIQHRTQKFFEMIESHPLSTKLLVPSLM 1000

  Fly   885 RFYVDVETTGQSTEFYDKFTIRYHISHLFKSMWENPIHRQAVICESRVGNQFVKFVNMLMNDTTF 949
            :||.|||.||.::|||||||||||||.:|||:|:|..|....:.|...|.|||:::|||:|||||
 Frog  1001 KFYTDVEHTGSTSEFYDKFTIRYHISTIFKSLWQNMAHHSTFMEEFNSGKQFVRYINMLINDTTF 1065

  Fly   950 LLDECLENLKRIHQTQQLLSDKANLSKMSAEQQQSRLTQLATDERQCRSYLTLARETVDLFHYLT 1014
            ||||.||:|||||:.|:.:.:|.:..::..:|||:|.:|||.|||..||||.||.||||:||.||
 Frog  1066 LLDESLESLKRIHEMQEEMRNKEHWEQLPRDQQQARQSQLAQDERVSRSYLALATETVDMFHILT 1130

  Fly  1015 SDIKEPFMRDELVDRLSSMLNFNLKQLAGPKCNDLKVKNPAKYGWEPRSLLAQIFDIYLHLDCDR 1079
            ..:::||:|.||..||::||||||:||.||||.||||:||.|||:||:.||.|:.||||||||.|
 Frog  1131 KQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDIYLHLDCAR 1195

  Fly  1080 FAEALAADERSFDVQICNEAASRIKRLALRSAVEVERFKALTQRAHEIYVTNLQTEDECADAPDE 1144
            ||:|:|.|:||:..::..|..|::|:..::|.:.:|:||.|.::..||...|.:.|.:.:|||||
 Frog  1196 FAKAIADDQRSYSKELFEEVISKMKKAGIKSTIAIEKFKLLAEKVEEIVARNARAEIDYSDAPDE 1260

  Fly  1145 FKDPLMDTLMSDPVVLPSGTVMDRAIITRHLLNSCTDPFNRQPLTEDMLVANIELKQRIDAWRKE 1209
            |:||||||||::||.|||||:|||:||.||||||.|||||||.|||:||....|||::|.||.::
 Frog  1261 FRDPLMDTLMTEPVRLPSGTIMDRSIILRHLLNSSTDPFNRQTLTENMLEPVPELKEKIQAWMRD 1325

  Fly  1210 QR 1211
            ::
 Frog  1326 KQ 1327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9934	NP_001162967.1	Ufd2P_core	510..1124	CDD:287392	272/633 (43%)
		U-box	1141..1211	CDD:252675	49/69 (71%)
ube4b	XP_031762209.1	Ufd2P_core	620..1240	CDD:402160	272/633 (43%)
		RING-Ubox_UBE4B	1253..1327	CDD:319572	50/73 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	514	1.000	Domainoid score	I319
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H107623
Inparanoid	1	1.050	711	1.000	Inparanoid score	I639
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D194967at2759
OrthoFinder	1	1.000	-	-		FOG0004816
OrthoInspector	1	1.000	-	-		oto102384
Panther	1	1.100	-	-	LDO	PTHR13931
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3397
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160