DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Yip1d1 and Yipf5

DIOPT Version :9

Sequence 1:	NP_609596.1	Gene:	Yip1d1 / 34696	FlyBaseID:	FBgn0032465	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_075800.1	Gene:	Yipf5 / 67180	MGIID:	1914430	Length:	257	Species:	Mus musculus

Alignment Length:	286	Identity:	127/286 - (44%)
Similarity:	172/286 - (60%)	Gaps:	51/286 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSQFGGPND-FYGSAPSADASYNFDMPEFGQELNFQTFDNTQASVPPNYDASYA----------- 53
            ||.|...|. ||      ..||:.|      |.:.|::|...:..|  |...||
Mouse     1 MSGFDNLNSGFY------QTSYSID------EQSQQSYDYGGSGGP--YSKQYAGCDYSQQGRFV 51

  Fly    54 -----QPPSQGLGGFYDPT-AYTDTS----YGQDKSGKSAAGGGAGNEFDDEPPLLEELGINPNH 108
                 ||.....|..|.|| ||..|:    |              |:.|::|||||||||||.:|
Mouse    52 PPDMMQPQQTYTGQIYQPTQAYPPTTPQPFY--------------GDSFEEEPPLLEELGINFDH 102

  Fly   109 IFQKTLAVLNPLRGTDQQILQDTDMAGPLVFCLTLGGFLLLSGKVTFSYIYGIGVMGCIFFYCLL 173
            |:||||.||:|||..|..|:.:||:|||:||||..|..|||:||:.|.|:|||..:||:..:|||
Mouse   103 IWQKTLTVLHPLRAADGSIMNETDLAGPVVFCLAFGATLLLAGKIQFGYVYGISAIGCLGMFCLL 167

  Fly   174 SLMVSRSQVTFGAVASVLGYCLLPMVVLSGINILITIQGTLGLIVSGISIFWCAISASKLFATAF 238
            :|| |.:.|:||.||||||||||||::||...::.::||.:|::::...|.||:.||||:|.:|.
Mouse   168 NLM-SMTGVSFGCVASVLGYCLLPMILLSSFAVVFSLQGMVGILLTATIIGWCSFSASKIFISAL 231

  Fly   239 SMDHQQLLIAYPCAVLYGGFALITIY 264
            :||.||||:|||||:|||.||||:::
Mouse   232 AMDGQQLLVAYPCALLYGVFALISVF 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yip1d1	NP_609596.1	Yip1	<95..264	CDD:304430	99/168 (59%)
Yipf5	NP_075800.1	Interaction with Sec23. /evidence=ECO:0000250	75..106		17/44 (39%)
Yipf5	NP_075800.1	Yip1	<96..257	CDD:389810	92/161 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838085
Domainoid	1	1.000	159	1.000	Domainoid score	I4081
eggNOG	1	0.900	-	-		E1_COG5080
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56969
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3526
Isobase	1	0.950	-	0	Normalized mean entropy	S991
OMA	1	1.010	-	-		QHG54466
OrthoDB	1	1.010	-	-		D1457080at2759
OrthoFinder	1	1.000	-	-		FOG0001876
OrthoInspector	1	1.000	-	-		otm43443
orthoMCL	1	0.900	-	-		OOG6_101570
Panther	1	1.100	-	-	O	PTHR21236
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1888
SonicParanoid	1	1.000	-	-		X1236
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750