DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Yip1d1 and yipf5

DIOPT Version :9

Sequence 1:	NP_609596.1	Gene:	Yip1d1 / 34696	FlyBaseID:	FBgn0032465	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_956589.1	Gene:	yipf5 / 393265	ZFINID:	ZDB-GENE-040426-1057	Length:	257	Species:	Danio rerio

Alignment Length:	277	Identity:	133/277 - (48%)
Similarity:	180/277 - (64%)	Gaps:	33/277 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSQFGGPN-DFYGSAPSAD----ASY---NFDMP--EFGQELNFQTFDNTQASVPPNYDAS--YA 53
            ||.|...| |||.|:.|.|    ..|   |.|.|  .:||      :|.:|   |..|.|:  ..
Zfish     1 MSGFDNFNTDFYQSSYSVDDQNQGGYGYSNTDEPYKPYGQ------YDYSQ---PVGYSAAPGMM 56

  Fly    54 QPPSQGLGGFYDPT-AYTDTSYGQDKSGKSAAGGGAGNEFDDEPPLLEELGINPNHIFQKTLAVL 117
            ||.....|..|.|| |:|.||   .:|..|::       |:||||||||||||.:||:||||..|
Zfish    57 QPQQPYTGQIYQPTPAFTPTS---SQSMYSSS-------FEDEPPLLEELGINFDHIWQKTLTAL 111

  Fly   118 NPLRGTDQQILQDTDMAGPLVFCLTLGGFLLLSGKVTFSYIYGIGVMGCIFFYCLLSLMVSRSQV 182
            :||:.:|..|:.:||:|||:||||..|..|||:||:.|.|:|||..:||:..|.||:|| |.:.|
Zfish   112 HPLKASDGSIMNETDLAGPMVFCLAFGATLLLTGKIQFGYVYGISAIGCLGMYSLLNLM-SMTGV 175

  Fly   183 TFGAVASVLGYCLLPMVVLSGINILITIQGTLGLIVSGISIFWCAISASKLFATAFSMDHQQLLI 247
            :||.||||||||||||::||...::.::||.:|:|::...|.||::||||:|.:|.:||.||||:
Zfish   176 SFGCVASVLGYCLLPMIILSSFGVIFSLQGIMGIILTAAIIGWCSLSASKIFISALAMDGQQLLV 240

  Fly   248 AYPCAVLYGGFALITIY 264
            |||||:|||.||||:::
Zfish   241 AYPCALLYGVFALISVF 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yip1d1	NP_609596.1	Yip1	<95..264	CDD:304430	98/168 (58%)
yipf5	NP_956589.1	Yip1	<89..257	CDD:304430	98/168 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581896
Domainoid	1	1.000	163	1.000	Domainoid score	I3923
eggNOG	1	0.900	-	-		E1_COG5080
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56969
Inparanoid	1	1.050	236	1.000	Inparanoid score	I3358
OMA	1	1.010	-	-		QHG54466
OrthoDB	1	1.010	-	-		D1457080at2759
OrthoFinder	1	1.000	-	-		FOG0001876
OrthoInspector	1	1.000	-	-		otm25876
orthoMCL	1	0.900	-	-		OOG6_101570
Panther	1	1.100	-	-	O	PTHR21236
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1888
SonicParanoid	1	1.000	-	-		X1236
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800