Protein Alignment Vha68-3 and VMA1

DIOPT Version :9

• Sequence 1: NP_609595.1
• Gene: Vha68-3 / 34695
• FlyBaseID: FBgn0032464
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: NP_010096.1
• Gene: VMA1 / 851342
• SGDID: S000002344
• Length: 1071
• Species: Saccharomyces cerevisiae
• Alignment Length: 1073
• Identity: 383/1073 - (35%)
• Similarity: 476/1073 - (44%)
• Gaps: 460/1073 - (42%)

  Fly   120 IEQVVDTHKYSSDEEEEEATMGRIFGVSGPVVNAEEMAGAAMYELVRVGHSQLVGEIIRLEGDMA 184
            ||......|..|.|:..|:..|.|:.||||||.||.|.|.||||||:|||..||||:||::||.|
Yeast     5 IENARKEIKRISLEDHAESEYGAIYSVSGPVVIAENMIGCAMYELVKVGHDNLVGEVIRIDGDKA 69

  Fly   185 TIQVYEDTSGVSVGDPVYQTGKPLSVELGPGIMGSIFDGIQRPLRSISELTNSIYVPKGIDTPSL 249
            ||||||:|:|::|||||.:||||||||||||:|.:|:|||||||::|.|.:.|||:|:|||||:|
Yeast    70 TIQVYEETAGLTVGDPVLRTGKPLSVELGPGLMETIYDGIQRPLKAIKEESQSIYIPRGIDTPAL 134

  Fly   250 PRNIAYEFTPGKLKIDALITGGDIYGSVFENSMMHDHRLILPPRTKGRIRWLAPPGNYCVDEVIV 314
            .|.|.::|||||.::...|:||||||||||||::..|:::||||::|.|.|:||.|.|.:||.|:
Yeast   135 DRTIKWQFTPGKFQVGDHISGGDIYGSVFENSLISSHKILLPPRSRGTITWIAPAGEYTLDEKIL 199

  Fly   315 ETEFNDEITKHTMLQVWPVRRCRPVEDKLPSNSPLLTGQRVLDAFFPCVQGGTTAIPGAFGCGKT 379
            |.||:.:.:..|:...||||..|||.:||.::.|||||||||||.|||||||||.||||||||||
Yeast   200 EVEFDGKKSDFTLYHTWPVRVPRPVTEKLSADYPLLTGQRVLDALFPCVQGGTTCIPGAFGCGKT 264

  Fly   380 VISQALSKYSNSDVIIYVG---------------------------------------------- 398
            ||||:||||||||.|||||
Yeast   265 VISQSLSKYSNSDAIIYVGCFAKGTNVLMADGSIECIENIEVGNKVMGKDGRPREVIKLPRGRET 329

  Fly   399 ----------------------------------------------------------------- 398
                                                                             
Yeast   330 MYSVVQKSQHRAHKSDSSREVPELLKFTCNATHELVVRTPRSVRRLSRTIKGVEYFEVITFEMGQ 394

  Fly   399 ----------------------------------------------------------------- 398
                                                                             
Yeast   395 KKAPDGRIVELVKEVSKSYPISEGPERANELVESYRKASNKAYFEWTIEARDLSLLGSHVRKATY 459

  Fly   399 ----------------------------------------------------------------- 398
                                                                             
Yeast   460 QTYAPILYENDHFFDYMQKSKFHLTIEGPKVLAYLLGLWIGDGLSDRATFSVDSRDTSLMERVTE 524

  Fly   399 ----------------------------------------------------------------- 398
                                                                             
Yeast   525 YAEKLNLCAEYKDRKEPQVAKTVNLYSKVVRGNGIRNNLNTENPLWDAIVGLGFLKDGVKNIPSF 589

  Fly   399 ----------------------------------------------------------------- 398
                                                                             
Yeast   590 LSTDNIGTRETFLAGLIDSDGYVTDEHGIKATIKTIHTSVRDGLVSLARSLGLVVSVNAEPAKVD 654

  Fly   399 ----------------------------------------------------------------- 398
                                                                             
Yeast   655 MNGTKHKISYAIYMSGGDVLLNVLSKCAGSKKFRPAPAAAFARECRGFYFELQELKEDDYYGITL 719

  Fly   399 ------------------CGERGNEMSEVLRDFPQLEVEVNGTMESIMKRTALVANTSNMPVAAR 445
                              ||||||||:|||.:||:|..|::||.|.|||||.|||||||||||||
Yeast   720 SDDSDHQFLLANQVVVHNCGERGNEMAEVLMEFPELYTEMSGTKEPIMKRTTLVANTSNMPVAAR 784

  Fly   446 EASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADAGYPAYLGARLASFYER 510
            ||||||||||:|||||.|.:|||:|||:||||||||||||||.|||||.|:||||||:|||||||
Yeast   785 EASIYTGITLAEYFRDQGKNVSMIADSSSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYER 849

  Fly   511 AGLVKCLGSPDREGSVSIVGAVSPPGGDFSDPVTSATLSIVQVFWGLDKKLAQRKHFPSVNWLQS 575
            ||....||||||.||||||.||||.|||||||||:|||.|.||||||||||||||||||:|...|
Yeast   850 AGKAVALGSPDRTGSVSIVAAVSPAGGDFSDPVTTATLGITQVFWGLDKKLAQRKHFPSINTSVS 914

  Fly   576 YSKYMRTLDTYYEESNPEFTHLRAKAKKVLQEEDDLAEIVQLVGKSSLNEEDKITLEVAKMLKDD 640
            ||||...|:.:|:.:.|||..||.:.|::|...::|.::|||||||:|::.|||||:||.::|:|
Yeast   915 YSKYTNVLNKFYDSNYPEFPVLRDRMKEILSNAEELEQVVQLVGKSALSDSDKITLDVATLIKED 979

  Fly   641 FLQQNSYSQYDAYCPFFKTIGMLKNMMTFYDAAILSVQNTADNEARVTWGLIRIKAANILYELST 705
            |||||.||.|||:||.:||..|::..::::|.|..:|.|.|:      |..:.....::.:.:|:
Yeast   980 FLQQNGYSTYDAFCPIWKTFDMMRAFISYHDEAQKAVANGAN------WSKLADSTGDVKHAVSS 1038

  Fly   706 MKFIDPKLGEATVLESMNKLHDNILSTFREIED 738
            .||.:|..||..|.....||...:...|.|..|
Yeast  1039 SKFFEPSRGEKEVHGEFEKLLSTMQERFAESTD 1071

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha68-3	NP_609595.1	V-ATPase_V1_A	141..729	CDD:273411	374/1041 (36%)
		ATP-synt_ab_N	143..205	CDD:280947	42/61 (69%)
		V_A-ATPase_A	207..579	CDD:238554	269/825 (33%)
		ATP-synt_ab_C	597..738	CDD:278722	54/140 (39%)
VMA1	NP_010096.1	V-ATPase_V1_A	24..>293	CDD:273411	171/268 (64%)
		Hom_end_hint	284..736	CDD:368334	0/451 (0%)
		V-ATPase_V1_A	<733..1063	CDD:273411	203/335 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343964
Domainoid	1	1.000	152	1.000	Domainoid score	I921
eggNOG	1	0.900	-	-		E1_COG1155
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S546
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001869
OrthoInspector	1	1.000	-	-		otm46705
orthoMCL	1	0.900	-	-		OOG6_100902
Panther	1	1.100	-	-	O	PTHR43607
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1565
TreeFam	1	0.960	-	-
	11	10.650