Protein Alignment Vha68-3 and Atp6v1a

DIOPT Version :10

• Sequence 1: NP_609595.1
• Gene: Vha68-3 / 34695
• FlyBaseID: FBgn0032464
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: NP_001101788.1
• Gene: Atp6v1a / 685232
• RGDID: 1596464
• Length: 617
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 448/608 - (73%)
• Similarity: 524/608 - (86%)
• Gaps: 3/608 - (0%)

  Fly   133 EEEEEATMGRIFGVSGPVVNAEEMAGAAMYELVRVGHSQLVGEIIRLEGDMATIQVYEDTSGVSV 197
            :|::|:|.|.:.|||||||.|.:|||||||||||||||:|||||||||||||||||||:||||||
  Rat    11 DEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSV 75

  Fly   198 GDPVYQTGKPLSVELGPGIMGSIFDGIQRPLRSISELTNSIYVPKGIDTPSLPRNIAYEFTPGK- 261
            ||||.:|||||||||||||||:|||||||||..||..|.|||:|:|::..:|.|:|.:||.|.|
  Rat    76 GDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWEFIPSKN 140

  Fly   262 LKIDALITGGDIYGSVFENSMMHDHRLILPPRTKGRIRWLAPPGNYCVDEVIVETEFNDEITKHT 326
            |::.:.||||||||.|.|||:: .|:::||||::|.:.::||||||...:|::|.||.....|.:
  Rat   141 LRVGSHITGGDIYGIVNENSLI-KHKIMLPPRSRGSVTYIAPPGNYDASDVVLELEFEGVKEKLS 204

  Fly   327 MLQVWPVRRCRPVEDKLPSNSPLLTGQRVLDAFFPCVQGGTTAIPGAFGCGKTVISQALSKYSNS 391
            |:||||||:.|||.:|||:|.|||||||||||.||||||||||||||||||||||||:|||||||
  Rat   205 MVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNS 269

  Fly   392 DVIIYVGCGERGNEMSEVLRDFPQLEVEVNGTMESIMKRTALVANTSNMPVAAREASIYTGITLS 456
            |||||||||||||||||||||||:|.:||:|.:||||||||||||||||||||||||||||||||
  Rat   270 DVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLS 334

  Fly   457 EYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADAGYPAYLGARLASFYERAGLVKCLGSPD 521
            |||||||||||||||||||||||||||||||||||||:||||||||||||||||||.|||||:|:
  Rat   335 EYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPE 399

  Fly   522 REGSVSIVGAVSPPGGDFSDPVTSATLSIVQVFWGLDKKLAQRKHFPSVNWLQSYSKYMRTLDTY 586
            |||||||||||||||||||||||||||.||||||||||||||||||||||||.|||||||.||.|
  Rat   400 REGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEY 464

  Fly   587 YEESNPEFTHLRAKAKKVLQEEDDLAEIVQLVGKSSLNEEDKITLEVAKMLKDDFLQQNSYSQYD 651
            |::...||..||.|||::||||:|||||||||||:||.|.|||||||||::||||||||.|:.||
  Rat   465 YDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYD 529

  Fly   652 AYCPFFKTIGMLKNMMTFYDAAILSVQNTADNEARVTWGLIRIKAANILYELSTMKFIDP-KLGE 715
            .:|||:||:|||.||::|||.|..:|:.||.::.::||.:||.....|||:||:|||.|| |.||
  Rat   530 RFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGEILYKLSSMKFKDPVKDGE 594

  Fly   716 ATVLESMNKLHDNILSTFREIED 738
            |.:.....:|.:::.:.||.:||
  Rat   595 AKIKADYAQLLEDMQNAFRSLED 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha68-3	NP_609595.1	V-ATPase_V1_A	141..729	CDD:273411	441/589 (75%)
Atp6v1a	NP_001101788.1	V-ATPase_V1_A	17..609	CDD:273411	442/592 (75%)