Protein Alignment Vha68-3 and atp6v1a

DIOPT Version :9

• Sequence 1: NP_609595.1
• Gene: Vha68-3 / 34695
• FlyBaseID: FBgn0032464
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: NP_001007512.1
• Gene: atp6v1a / 493238
• XenbaseID: XB-GENE-479548
• Length: 617
• Species: Xenopus tropicalis
• Alignment Length: 608
• Identity: 444/608 - (73%)
• Similarity: 515/608 - (84%)
• Gaps: 3/608 - (0%)

  Fly   133 EEEEEATMGRIFGVSGPVVNAEEMAGAAMYELVRVGHSQLVGEIIRLEGDMATIQVYEDTSGVSV 197
            :||.|:..|.:.|||||||.|..||||||||||||||.:|||||||||||||||||||:||||.|
 Frog    11 DEERESQFGYVHGVSGPVVTASNMAGAAMYELVRVGHCELVGEIIRLEGDMATIQVYEETSGVCV 75

  Fly   198 GDPVYQTGKPLSVELGPGIMGSIFDGIQRPLRSISELTNSIYVPKGIDTPSLPRNIAYEFTPGK- 261
            ||||.:|||||||||||||||||||||||||:.||:.|.|||:|:||:..:|.::|.:||.|.|
 Frog    76 GDPVLRTGKPLSVELGPGIMGSIFDGIQRPLKDISDSTQSIYIPRGINVSALSKDIKWEFNPSKS 140

  Fly   262 LKIDALITGGDIYGSVFENSMMHDHRLILPPRTKGRIRWLAPPGNYCVDEVIVETEFNDEITKHT 326
            :::.:.||||||||:|.|||::. |:::||||.:|.:.::||||:|...:|::|.||.....|.|
 Frog   141 IRVGSHITGGDIYGAVMENSLIR-HKIMLPPRNRGTVTYIAPPGHYDTSDVVLELEFEGVKDKFT 204

  Fly   327 MLQVWPVRRCRPVEDKLPSNSPLLTGQRVLDAFFPCVQGGTTAIPGAFGCGKTVISQALSKYSNS 391
            |:||||||..|||.:|||:|.|||||||||||.||||||||||||||||||||||||:|||||||
 Frog   205 MVQVWPVRSIRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNS 269

  Fly   392 DVIIYVGCGERGNEMSEVLRDFPQLEVEVNGTMESIMKRTALVANTSNMPVAAREASIYTGITLS 456
            |||||||||||||||||||||||:|.:||:|..||||||||||||||||||||||||||||||||
 Frog   270 DVIIYVGCGERGNEMSEVLRDFPELTMEVDGKTESIMKRTALVANTSNMPVAAREASIYTGITLS 334

  Fly   457 EYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADAGYPAYLGARLASFYERAGLVKCLGSPD 521
            |||||||||||||||||||||||||||||||||||||:||||||||||||||||||.|||||:|:
 Frog   335 EYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPE 399

  Fly   522 REGSVSIVGAVSPPGGDFSDPVTSATLSIVQVFWGLDKKLAQRKHFPSVNWLQSYSKYMRTLDTY 586
            |||||||||||||||||||||||||||.||||||||||||||||||||||||.|||||.|.||.|
 Frog   400 REGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYTRALDEY 464

  Fly   587 YEESNPEFTHLRAKAKKVLQEEDDLAEIVQLVGKSSLNEEDKITLEVAKMLKDDFLQQNSYSQYD 651
            |::...||..||.|||::||||:|||||||||||:||.|.|||||||||::||||||||.|:.||
 Frog   465 YDKHFQEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYD 529

  Fly   652 AYCPFFKTIGMLKNMMTFYDAAILSVQNTADNEARVTWGLIRIKAANILYELSTMKFIDP-KLGE 715
            .:|||:||:|||.||:.|||.|..:|..||.::.::||.:||.....|||.|::|||.|| |.||
 Frog   530 RFCPFYKTVGMLYNMIAFYDMARRAVDTTAQSDNKITWSIIREHMGEILYRLTSMKFKDPVKEGE 594

  Fly   716 ATVLESMNKLHDNILSTFREIED 738
            |.:.....:|.:::.:.||.:||
 Frog   595 AKIKADYAQLLEDMQNAFRSLED 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha68-3	NP_609595.1	V-ATPase_V1_A	141..729	CDD:273411	437/589 (74%)
		ATP-synt_ab_N	143..205	CDD:280947	50/61 (82%)
		V_A-ATPase_A	207..579	CDD:238554	296/372 (80%)
		ATP-synt_ab_C	597..738	CDD:278722	80/141 (57%)
atp6v1a	NP_001007512.1	V-ATPase_V1_A	17..609	CDD:273411	437/592 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	105	1.000	Domainoid score	I6554
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60789
OrthoDB	1	1.010	-	-		D160349at33208
OrthoFinder	1	1.000	-	-		FOG0001869
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43607
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1565
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.030