DRSC/TRiP Functional Genomics Resources

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Protein Alignment ACXC and Gucy1a2

DIOPT Version :9

Sequence 1:NP_609593.1 Gene:ACXC / 34689 FlyBaseID:FBgn0040508 Length:1130 Species:Drosophila melanogaster
Sequence 2:NP_076446.1 Gene:Gucy1a2 / 66012 RGDID:621655 Length:730 Species:Rattus norvegicus


Alignment Length:242 Identity:65/242 - (26%)
Similarity:119/242 - (49%) Gaps:32/242 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   243 LDRHQFIMEETWLRHALLQES-----ILLDSILPPQIAKPVQEKIKSKITQSENSPDRFQMGPRT 302
            :|:.:..:|:|   |..|:|.     .||.||.|..:|:.:.:              |.|:..|.
  Rat   467 MDKLKATLEKT---HQALEEEKKKTVDLLYSIFPGDVAQQLWQ--------------RQQVQARK 514

  Fly   303 TESFMAIQIHPDVSILYADVVNYTHLTTTLTVGNLVKVLHDLYGRFDIAASNFKVQRIKFLGDCY 367
            .:         ||::|::|:|.:|.:....|...::.:|::||.|||.......:.:::.:||.|
  Rat   515 FD---------DVTMLFSDIVGFTAICAQCTPMQVISMLNELYTRFDHQCGFLDIYKVETIGDAY 570

  Fly   368 YCVAGLTTPDPDHAKCCVSLGISMISNIQEVRAERGLDIDMRIGVHSGSLLAGIIGEAKLQFDIW 432
            ...:||......|||....:.:.|:...:||....|..|.||||:||||:|||::|....::.::
  Rat   571 CVASGLHRKSLCHAKPIALMALKMMELSEEVLTPDGRPIQMRIGIHSGSVLAGVVGVRMPRYCLF 635

  Fly   433 GTDVEIANHLESTGEPGYVHVSGRTLSMLNPAD-YTILSGTQKAQSD 478
            |.:|.:|:..||...|..:::|..|..:|...| :|.:..:::...|
  Rat   636 GNNVTLASKFESGSHPRRINISPTTYQLLKREDSFTFIPRSREELPD 682

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ACXCNP_609593.1 AC_N <33..285 CDD:292831 12/46 (26%)
CYCc 293..468 CDD:214485 51/175 (29%)
Nucleotidyl_cyc_III 307..466 CDD:299850 48/159 (30%)
CYCc 833..1060 CDD:214485
Nucleotidyl_cyc_III 861..1085 CDD:299850
Gucy1a2NP_076446.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..53
HNOB <157..268 CDD:285002
HNOBA 314..501 CDD:285003 11/36 (31%)
CYCc 483..672 CDD:214485 58/211 (27%)
Guanylate_cyc 512..696 CDD:278633 51/180 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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