DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXC and CG34357

DIOPT Version :9

Sequence 1:	NP_609593.1	Gene:	ACXC / 34689	FlyBaseID:	FBgn0040508	Length:	1130	Species:	Drosophila melanogaster
Sequence 2:	NP_001356914.1	Gene:	CG34357 / 5740349	FlyBaseID:	FBgn0085386	Length:	1689	Species:	Drosophila melanogaster

Alignment Length:	341	Identity:	83/341 - (24%)
Similarity:	153/341 - (44%)	Gaps:	71/341 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 FNMMGIFFRIMN--------DTMVRASFLDRHQFIMEETWLRHALLQESI-------LLDSILPP 272
            ||.:...|:::|        |||.:  .|:::...:||. :|....|..|       ||:.:||.
  Fly  1028 FNSVYERFKMLNHGRKVNFVDTMFQ--MLEKYSNNLEEL-IRERTEQLDIERKKTEQLLNRMLPS 1089

  Fly   273 QIAKPVQEKIKSKITQSENSPDRFQMGPRTTESFMAIQIHPDVSILYADVVNYTHLTTTLTVGNL 337
            .:|    ||:|..:..   .|:.|.                ||:|.::|:|.:|.:....:...:
  Fly  1090 SVA----EKLKMGLAV---DPEEFS----------------DVTIYFSDIVGFTTIAAHCSPVQV 1131

  Fly   338 VKVLHDLYGRFDIAASNFKVQRIKFLGDCYYCVAGLTTPDPDHAKCCVSLGISMI--SNIQEVRA 400
            |.:|:|||..||...:.:.|.:::.:||.|..|:||....||||:...::.:.::  |....|:.
  Fly  1132 VDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLPVKIPDHAEQIATMALDLLHQSGRFNVKH 1196

  Fly   401 ERGLDIDMRIGVHSGSLLAGIIGEAKLQFDIWGTDVEIANHLESTGEPGYVHVSGRTLSMLN--- 462
            ..|:.:.:|||:|:|...||::|....::.::|..|..|:.:||||....:|:|..|...|:
  Fly  1197 LPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDRLDARG 1261

  Fly   463 -----PADYTILSGTQKAQSDPVLQYIHTYLLTGQVARESFITS---IGG--------VRSSSVL 511
                 |.....:.|.         ..::|:.|.|:...:..:.:   ||.        :|:|..|
  Fly  1262 GYAIEPRGLIDIKGK---------GMMNTFWLLGKKGFDKPLPAPPPIGESHGLDESLIRNSITL 1317

  Fly   512 EVKSIDRIRSSRPSQS 527
            :.::.....|:.||.|
  Fly  1318 KAQANKSRTSTNPSSS 1333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	AC_N	<33..285	CDD:292831	21/76 (28%)
		CYCc	293..468	CDD:214485	49/184 (27%)
		Nucleotidyl_cyc_III	307..466	CDD:299850	47/168 (28%)
		CYCc	833..1060	CDD:214485
		Nucleotidyl_cyc_III	861..1085	CDD:299850
CG34357	NP_001356914.1	PKc_like	763..1041	CDD:354810	4/12 (33%)
CG34357	NP_001356914.1	CYCc	1074..1266	CDD:214485	57/214 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810