DRSC/TRiP Functional Genomics Resources

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Protein Alignment ACXC and NPR3

DIOPT Version :10

Sequence 1:NP_609593.1 Gene:ACXC / 34689 FlyBaseID:FBgn0040508 Length:1130 Species:Drosophila melanogaster
Sequence 2:NP_001191304.1 Gene:NPR3 / 4883 HGNCID:7945 Length:541 Species:Homo sapiens


Alignment Length:170 Identity:32/170 - (18%)
Similarity:58/170 - (34%) Gaps:67/170 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   265 LLDSILPPQIAKPVQEKIKSKITQSENSPDRFQMGPRTTESFMAIQIHPDVSILYADVV------ 323
            |:|.:...:.|||  :.|...:.:...:|            ...:..|.|:.:|.|..:      
Human   116 LVDRVAAARGAKP--DLILGPVCEYAAAP------------VARLASHWDLPMLSAGALAAGFQH 166

  Fly   324 ---NYTHLTTT----LTVGNLVKVL--HDLYGRFDIAASNFKVQRIKFLGDCYYCVAGLTTPDPD 379
               .|:|||..    ..:|.::..|  |..:.|..:..|:.|::|     :||:.:.|       
Human   167 KDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLER-----NCYFTLEG------- 219

  Fly   380 HAKCCVSLGISMISNIQEVRAERGL-----------DIDM 408
                           :.||..|.||           |:|:
Human   220 ---------------VHEVFQEEGLHTSIYSFDETKDLDL 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ACXCNP_609593.1 Nucleotidyl_cyc_III 307..466 CDD:448371 25/128 (20%)
Nucleotidyl_cyc_III 861..1085 CDD:448371
NPR3NP_001191304.1 PBP1_NPR_C 51..446 CDD:380609 32/170 (19%)
TM_EphA1 476..507 CDD:214014
Blue background indicates that the domain is not in the aligned region.

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