DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXC and Gycbeta100B

DIOPT Version :9

Sequence 1:	NP_609593.1	Gene:	ACXC / 34689	FlyBaseID:	FBgn0040508	Length:	1130	Species:	Drosophila melanogaster
Sequence 2:	NP_524603.2	Gene:	Gycbeta100B / 43682	FlyBaseID:	FBgn0013973	Length:	787	Species:	Drosophila melanogaster

Alignment Length:	306	Identity:	82/306 - (26%)
Similarity:	135/306 - (44%)	Gaps:	82/306 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   799 LTMYAKERQSEFNTKMNYKLNVD-LQNKQKAADLTNQSIIILLNNILPSHVVDLYLNSLAKHE-- 860
            |.:.:::.::|:....|.::..| ||...:..:...|....||.::||..|.    |.| :|:
  Fly   462 LVLLSEKFEAEYKLTKNLEMLTDKLQQTFRDLESEKQKTDRLLYSVLPKSVA----NEL-RHQRP 521

  Fly   861 LYYENYRMVSVMFAMLINFPM----------NLPSLRVLNDIITQFDRLLTAYREYYVVEKIKVV 915
            :..:.|..|::||:.::.|..          .:..:::||::.|.||.|..:.|...|. |::.|
  Fly   522 VPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELYTVFDALTDSKRNLNVY-KVETV 585

  Fly   916 GCTYMAACGLDFNLASNIRQTDHFRNSSLHVEVEHARNHRMTDENYDSDMNNDEVVFIMTTFALD 980
            |..|||..||          .||..        :||:                    .|...|||
  Fly   586 GDKYMAVSGL----------PDHCE--------DHAK--------------------CMARVALD 612

  Fly   981 LMRTLAACNRAYSSSFFERSLSQG----KICIGISSGEIMAGVVGASQPHYDIWGNPVNMASRME 1041
            :|.             ..:::..|    :|.|||.|||::.||:|...|.|.::||.||:.||.|
  Fly   613 MMD-------------MAKNVKMGSNPVQITIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTE 664

  Fly  1042 STGLPGHIQVTEESAKIL-----QEFDIKCIYRGMTFVKGRGDIPT 1082
            :||:||.|.|:||:.::|     |:......|||...:||:   ||
  Fly   665 TTGVPGRINVSEETYRLLCMAINQDDSFHLEYRGPVIMKGK---PT 707

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	AC_N	<33..285	CDD:292831
		CYCc	293..468	CDD:214485
		Nucleotidyl_cyc_III	307..466	CDD:299850
		CYCc	833..1060	CDD:214485	68/247 (28%)
		Nucleotidyl_cyc_III	861..1085	CDD:299850	67/241 (28%)
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:285002
		HNOBA	326..516	CDD:285003	13/57 (23%)
		CYCc	496..688	CDD:214485	68/248 (27%)
		Guanylate_cyc	522..714	CDD:278633	67/241 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453957
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740