Protein Alignment ACXC and Ac78C

DIOPT Version :10

• Sequence 1: NP_609593.1
• Gene: ACXC / 34689
• FlyBaseID: FBgn0040508
• Length: 1130
• Species: Drosophila melanogaster
• Sequence 2: NP_001262138.1
• Gene: Ac78C / 40333
• FlyBaseID: FBgn0024150
• Length: 1727
• Species: Drosophila melanogaster
• Alignment Length: 1376
• Identity: 331/1376 - (24%)
• Similarity: 525/1376 - (38%)
• Gaps: 417/1376 - (30%)

  Fly    36 LREKCKELNLEEEYRYY-----QVRLMVSNLTIFYVLFIILAMSFL--TIELLYVQHYNAVFFNF 93
            |....|:.:||..|..|     |..|::.|: :.:||.|:||..::  ..||..::..:......
  Fly   303 LTNSFKQSSLERSYLTYTHRQRQKSLIIVNV-VDFVLKIVLAFVWIMRRSELGPIESDDGTSMAT 366

  Fly    94 VI--RVVSTILVLTVLSINFCEKFVSRH-RWVMIASSVL---------------SVYLVVLTDIV 140
            .|  .|...|..:.:..:.:...|.:.: .|..:.:.||               ..|||
  Fly   367 AITWSVCCGIANMAICFLGYWRCFANNYLHWAAVCTWVLFNIQGFVGQGVGFADREYLV------ 425

  Fly   141 MISYHFYKNDWPLNTSFDVFTLCMIYMFLPIP---SIKGAALLAS-SVSLIYVAFFMH-SLTFNA 200
                      |     :.:|.:.:.|..||:|   .:.|..:.|| .:::|.:....| ..|.|.
  Fly   426 ----------W-----YILFVIFVPYAMLPLPLKWCVVGGTITASCHLAVITIIKLQHGEATINP 475

  Fly   201 VYTDRDSFGYDVISTDILHNLGFNMMGIFFRIMNDTMVRASFLDRHQFIMEETWLRHALLQESIL 265
                 :...:.:.:..||:. ..|:.|::.:.:.|...|.:|::.|:.:..:......|.:...|
  Fly   476 -----ECVLFQIFANFILYT-AINVAGMYTKYLTDRGQRLAFIETHKAMEHKKESEKELQRTQKL 534

  Fly   266 LDSILPPQIAKPVQEKIKSKITQSENSPDRFQMGPRTTESFMAIQIHP--DVSILYADVVNYTHL 328
            ||||||    ..|..:|:|::.:..:        |.....|..:.::|  :||||:||:..:|.|
  Fly   535 LDSILP----NIVNNQIRSEMYKGTD--------PTVETQFNKLYVYPMDNVSILFADIKGFTEL 587

  Fly   329 TTTLTVGNLVKVLHDLYGRFDIAASNFKVQRIKFLGDCYYCVAGLTTPD----PDHAKCCVSLGI 389
            .:..:...|||:|:||:.|||..|.:....|:|.||||||||:...:.:    ||||.|.|..|:
  Fly   588 ASKTSAQQLVKILNDLFARFDRIAEDNHCLRVKLLGDCYYCVSQFESDNWKTRPDHAVCSVETGL 652

  Fly   390 SMISNIQEVRAERGLDIDMRIGVHSGSLLAGIIGEAKLQFDIWGTDVEIANHLESTGEPGYVHVS 454
            .||..|::||....:|::||||:||||::.|::|..|..||:|..||.||||:||.|.||.||:|
  Fly   653 HMIKAIKDVRLHTHVDLNMRIGIHSGSVMCGVLGNKKWHFDVWSNDVIIANHMESGGIPGRVHIS 717

  Fly   455 GRTLSMLNPADYTILSGTQKAQSDPV-LQYIHTYL--------------------LTGQVA---- 494
            ..||..||.| |.:..|....:.:.: :..:.|||                    |.|.||
  Fly   718 EATLKCLNDA-YEVEPGNGGCRDNHLKMLNVKTYLIKRTEPLRPKRRFGTRSSAHLAGSVATAAP 781

  Fly   495 ------------RESFITSIGGVRSS--------------------------------------- 508
                        ..|...|||||.::
  Fly   782 PCATPTALPKSISASGSGSIGGVTATGNDGASIDGRSLEYAATIAVPAQQPTQLLQQQQKKNISL 846

  Fly   509 ----SVLEVKSID--RIRSS--------------------------------------RP----- 524
                :|:|..::|  |||:.                                      ||
  Fly   847 NSLPNVVEGVAMDSRRIRNGCGVMGGAGGTGGGGTGPCGMSTVSSPTAMMSAPLEVQLRPRNGAC 911

  Fly   525 ----------------SQSSMTDEFRE-EFRNM--PVGGIN-----------------------L 547
                            ...|.||...| .|:|:  |..|:|                       :
  Fly   912 SIQNLAEAIDGKGLIIEDESTTDWIPEIPFKNLNSPEDGLNRADSILVDTKEDHRVSVAVLDEEI 976

  Fly   548 NSPCCRRTRLDTHKKTQRE-IGIFCAAFKDSSLEWNYLHQPDFIFKSSMLLAWGIGCCLIYIQIV 611
            :....:..:::::|:.:|| :..:...|||.|.|..:....:.:|:|:||..:.|...::..|::
  Fly   977 DEFIEQNIQINSNKEIRREYLNPWTLKFKDKSQEQKFCQLREDMFRSNMLCVFVIWIFMVLCQVI 1041

  Fly   612 TNNFSCT---ACIVVDLVTFFFLTSLL----------CLAWYKNVCWWKSGRYEFRIYGKY--SC 661
            ... .||   .|:.|..|...|...|:          ||.........:..|....|.|..  .|
  Fly  1042 IIP-RCTRLIICLSVGTVILTFCCVLVMAEEFPGLPRCLKTNSAKLVHQRQRRTLFICGVIVSMC 1105

  Fly   662 M-----------AFHIFEKIQHSVSLR----------------ITVYLGILFSYYAVIS------ 693
            |           :.:|....:||..||                :.|||.....:...||
  Fly  1106 MLSAIGLVLCPSSTYIGTADEHSRFLRMVSPYSNISMTEKEFKLNVYLSATIHHNITISTPASGG 1170

  Fly   694 ----------------------LIMLNC------------------DRDMYELSYIESKIYHYEM 718
                                  .:.||.                  ...:..|||.::.:.....
  Fly  1171 PTPLVDITSSGPSDEFVRSTLNALTLNLTPPLPQSHRPYTLTTNGHSVSLSNLSYSDASVMQSSS 1235

  Fly   719 D-RDTCFHP--WVFTNMISLILGISYTFARIPFGLKIVISCCETLAYLLIVFFQFAFIFQHSATT 780
            | ...|.||  .|||.::.|:        .:...||:.. ..:.|..|.:|.|....|.....:.
  Fly  1236 DVEGQCAHPEYLVFTWVLCLV--------SLATALKLYY-LVKALMALAMVAFYTTLIMMKFGSG 1291

  Fly   781 TPFMKAELAH----------CLRVCMMLLTMYAKERQSEFNTKMNYKLNVDLQNKQKAADLTNQS 835
            ..|...||:.          .|.:..:::..| ..|..|..:::::     :..:|...:|||..
  Fly  1292 DSFSLVELSRLGMPLGVQMLILLISFLVMVCY-HARLVEVTSRLDF-----IWKEQAERELTNMK 1350

  Fly   836 IIILLN-----NILPSHVVDLYLNSLAKHELYYENYRMVSVMFAMLINF--------PMNLPSLR 887
            ....||     ||||.||...||:.....|||.:.:.:..||||.:.||        ......:|
  Fly  1351 SNRALNDTLIKNILPDHVATYYLSDEHTDELYSKMHNLCGVMFASIPNFQDFYSEDIDNGKACIR 1415

  Fly   888 VLNDIITQFDRLLTAYREYYVVEKIKVVGCTYMAACGLDFNLASNIRQTDHFRNSSLHVEVEHAR 952
            :||:||..||.||...| :..|||||.||.|||||.||:.                     ||.|
  Fly  1416 ILNEIICDFDELLEEPR-FASVEKIKTVGATYMAAAGLNH---------------------EHLR 1458

  Fly   953 NHRMTDENYDSDMNNDEVVFIMTTFALDLMRTLAACNRAYSSSFFERSLSQGKICIGISSGEIMA 1017
            ....|.|:...|         :..||..:.:.|...|....::|        ::.:||.||.:::
  Fly  1459 LRGETSEDSVCD---------LVEFAFAMKQKLEEINGDAFNNF--------QLRVGICSGPLVS 1506

  Fly  1018 GVVGASQPHYDIWGNPVNMASRMESTGLPGHIQVTEESAKILQEFDIKCIYRGMTFVKGRGDIPT 1082
            ||:||.:|.||||||.||:||||:|||....:||.|.:|::|......|:.||...|||:|.:.|
  Fly  1507 GVIGARKPVYDIWGNTVNVASRMDSTGENWRVQVPENTAELLCSRGYTCVKRGEIAVKGKGMMTT 1571

  Fly  1083 YFV---GIDEN 1090
            ::|   ||.|:
  Fly  1572 FYVHPKGISES 1582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	Nucleotidyl_cyc_III	307..466	CDD:448371	75/164 (46%)
		Nucleotidyl_cyc_III	861..1085	CDD:448371	80/231 (35%)
Ac78C	NP_001262138.1	AC_N	<216..551	CDD:318454	58/279 (21%)
		Guanylate_cyc	566..753	CDD:425528	80/187 (43%)
		Adcy_cons_dom	929..1021	CDD:461877	17/91 (19%)
		Guanylate_cyc	1381..1576	CDD:425528	81/233 (35%)