Protein Alignment ACXC and Ac13E

DIOPT Version :9

• Sequence 1: NP_609593.1
• Gene: ACXC / 34689
• FlyBaseID: FBgn0040508
• Length: 1130
• Species: Drosophila melanogaster
• Sequence 2: NP_001259575.1
• Gene: Ac13E / 32485
• FlyBaseID: FBgn0022710
• Length: 1703
• Species: Drosophila melanogaster
• Alignment Length: 1614
• Identity: 339/1614 - (21%)
• Similarity: 556/1614 - (34%)
• Gaps: 649/1614 - (40%)

  Fly    23 LDYANERLWEHSYLREKCKELNLEEEYR---YYQVRLMVSNLTIFYVLFIILAMSFLTIELLYVQ 84
            |..|.||....|:|..|.....|||:|:   :..|| |....|:.|:|...|......:    |.
  Fly    57 LPVAFERAAAKSWLDPKFDSPVLEEQYQASVFPHVR-MRYRFTLSYILLCSLMWCLYFV----VD 116

  Fly    85 HYNAVFFNFVIRVVSTILVLTVLSINFCEKFVSR-HRWVMIASSVLSVYLVVLTDIVMISYHFYK 148
            ..:..|:..:....|.:.::|::::.|....:.| ||.|   :|.::..|:....:..::|
  Fly   117 GGSEDFWRPISSSFSMLSLVTIMALCFTHWDLYREHRTV---TSAVTALLLCGASLAFLTY---- 174

  Fly   149 NDWPLNTSFDV---FTLC-----MIYMFLPIPSIKGAALLAS-SVSLIYVAFF-----------M 193
                ...:|..   |.:|     :||..||:|...||:...| |::...|:..           |
  Fly   175 ----TGRAFSPLGHFAICLEIVLLIYTALPMPLWLGASTAISYSIAFEMVSHMVIGCSAIHGGPM 235

  Fly   194 H---------SLTFNAVYTDRDSFGYDVISTDILHNLGFNMMGIFFRIMNDTMVRASF------- 242
            |         .:..|...::|      ::...|:.:|..:::|:...|||...:|.:|
  Fly   236 HGGGGAAGGSGMEANGDPSNR------ILILRIMAHLSVHLVGVHVLIMNLVRMRGTFMKVGQNL 294

  Fly   243 LDRHQFIMEETWLRHALLQESILLDSILPPQIAKP-VQEKIKSKITQSENSPDRFQMGPRTTES- 305
            |.|.|..||:.      |:|. ::.|::||::|.. :.|...|.:......|:...|.||.:..
  Fly   295 LVRRQLEMEKQ------LKEK-MIHSVMPPKVADMLLNEGGPSGLDAGGLPPESHYMRPRASNDV 352

  Fly   306 ---FMAIQIH--PDVSILYADVVNYTHLTTTLTVGNLVKVLHDLYGRFDIAASNFKVQRIKFLGD 365
               |....:|  .:||||:||:|.:|.:::|.|...||::|:||:.|||...|....::|..|||
  Fly   353 KSLFRPFHMHSMENVSILFADIVGFTRMSSTKTAEQLVEILNDLFERFDDLCSLSGCEKISTLGD 417

  Fly   366 CYYCVAGLTTPDPDHAKCCVSLGISMISNIQEVRAERGLDIDMRIGVHSGSLLAGIIGEAKLQFD 430
            |||||:|...|..|||.|||.:|:.||..::...|:|...:.||:|||:|::|.||:|..:::||
  Fly   418 CYYCVSGCPEPRADHAICCVEMGLGMIDAMRCFDAQRHEGVKMRVGVHTGTVLCGIVGTRRVKFD 482

  Fly   431 IWGTDVEIANHLESTGEPGYVHVSGRTLSMLNPA----------------------DYT------ 467
            :|..||.:||.:||:|:|..||:|..|.|.|..|                      |:|
  Fly   483 VWSNDVSLANKMESSGKPEQVHISQETSSFLGDAYYLEEGEEVFGHRTYFVVGRRRDFTRTNSLS 547

  Fly   468 ------------ILSGTQKA---QS--------------------------DPVLQ--------- 482
                        :|.|...|   ||                          .|||.
  Fly   548 PSMPANATGSSLLLPGAHGASLSQSATNVSAVQPNVPPASPVGQLSSSLNPSPVLSMRPRLTSLS 612

  Fly   483 -----------------YIH---------------------TYLLTGQV---------------- 493
                             .||                     |..|.|.:
  Fly   613 MKMRKKSQSRDRDVERGIIHPAAAGIPPVIVVRERPKIIITTKSLPGSLDSDEQPPVSPPLLPPA 677

  Fly   494 ---ARES-------------FI---------TSIGGVRSSSVLE--------------------- 512
               |.|:             |:         :|.||..|:..|:
  Fly   678 NPPAAETRSKIKLKVWKIPRFLKRFEDLTNRSSCGGSSSAGHLDKEREREREKEKEELHQHNQLN 742

  Fly   513 --------------------------VKSIDR--------------------------IRSSR-- 523
                                      |:|..|                          :||..
  Fly   743 PEETLAFMDNQMQNGNGCGYQQLPVLVESNHRTQTLDIPAARPVLHHAATSTALASSVLRSPEAG 807

  Fly   524 ---------PSQSSMTDE-----------------------FREEFRNMPVGGIN---------- 546
                     |.|.||.|:                       :|.:......||:|
  Fly   808 VSGGGGCCSPGQYSMYDDIIDVRSYISQSRSDISPFGRSGSYRSQCGRQSTGGVNGAGPAGVGAE 872

  Fly   547 ----------------------------------------LNSPCC------------------- 552
                                                    ..||||
  Fly   873 GRAGTSQTAPPVEQSPLPRPRASTLATGRPTPNSLEPGPSSTSPCCLPAPGNSVGGGGIFPPTHS 937

  Fly   553 RRTRLDTHKKTQREIGIFCAAFKDSSLEWNYL--------HQPDFIFKS---------------- 593
            |::.:.....::::.||...:.:.|..:..|.        |:....|.|
  Fly   938 RQSSICPSATSRKDSGIKSNSRRSSIQQQIYALNQTAISQHRVSGYFTSSTSSISNLGEVQGLGL 1002

  Fly   594 ---------------SMLLAWGIGCCLIYIQ----------IVTNNFSCTACIVVDLVTFFFLTS 633
                           |..:|..:..||..::          :..|..|..:.:|...:..|.|
  Fly  1003 PLAVQPPPPLLMPACSSQMADPLAACLQQLRKQSDLQLIRCVRDNARSQRSYLVKPPLRKFSL-- 1065

  Fly   634 LLCLAWYKNVCWWKSGRYE--FRI----YGK---------------------------YSCMAFH 665
                       ::||.:.|  ||.    :|.                           |.|::..
  Fly  1066 -----------YFKSRQLERDFRSKAHRFGAENETEGPPTLATPRYNTYIDIFVGIAVYLCISVS 1119

  Fly   666 IFEKIQHSV--SLRITVYLGILFSYYAVISLIMLN---CDRDMYELSYIESKIY----------- 714
            :|...|::|  |.|:.|.|...|:...|.:|.:..   |.|.  ..|.:.::..
  Fly  1120 LFLMTQNTVSPSFRLWVTLFSCFTGIQVFALFLFTRQMCRRQ--SGSNVSNRFRSKSTTSEDLER 1182

  Fly   715 -----------HYEMDRDTCF------HPW--------------VFTNMISLIL----GISYTFA 744
                       |:|...|..|      :||              :..|.:.|.|    ...|.:.
  Fly  1183 DERGAAPGGRPHFESCADRIFEAISSWYPWHICLAVLMAMPVLLIIANFLLLDLEQLEAFEYHYG 1247

  Fly   745 RIPFGLKIVISC------C---ETLAYLLIVFF-----QFAFIFQHSATTTP------------- 782
            .:.| :.||..|      |   ..||:|..:.|     ....::.|:.:...
  Fly  1248 FLIF-VCIVHFCNFTQLNCWVRNVLAFLAALCFIGIAVSQLMVYSHNRSDQQQDQEASNFIQEIK 1311

  Fly   783 -FMKAELAHCLRVCMMLLTMYAKERQSEFNTKMNYKLN-VDLQNKQKAADLTNQSIIILLNNILP 845
             |....:...|.:.::|:.::...|:.|...::.:..| |..|:|.:..::.||: .:||:||:|
  Fly  1312 WFQDYHVEIYLDLLLILVLVWFLNREFEIGYRLTFYGNAVANQDKVRVQNMKNQA-DMLLHNIIP 1375

  Fly   846 SHVVDLYLNSLAKHELYYENYRMVSVMFAMLINFPMNLPS--------LRVLNDIITQFDRLLTA 902
            .||.: :|.:.||   |.||:..::::||.::||......        |||||::|..||.||:.
  Fly  1376 KHVAE-HLKNTAK---YSENHHNIAIIFASIVNFNEMYDESYLGGKEFLRVLNELIGDFDELLSR 1436

  Fly   903 YREYYVVEKIKVVGCTYMAACGLDFNLASNIRQTDHFRNSSLHVEVEHARNHRMTDENYDSDMNN 967
             .|:..|||||.:|.|:|||.|||                         .:||.|         .
  Fly  1437 -PEFRAVEKIKTIGSTFMAASGLD-------------------------PSHRGT---------G 1466

  Fly   968 DEVVFIMTTFALDLMRTLAACNRAYSSSFFERSLSQGKICIGISSGEIMAGVVGASQPHYDIWGN 1032
            ||.:..:..|::.:...:.|.|:    ...|.:|.   :.||::.|::.|||:|.|:.:|||||:
  Fly  1467 DEHIHTLMEFSIAMQEVVDAFNK----DLLEFNLI---LRIGMNIGDVTAGVIGTSKLYYDIWGD 1524

  Fly  1033 PVNMASRMESTGLPGHIQVTEESAKIL---QEFDIKCIYRGMTFVKGRGDIPTY 1083
            .||:||||:|||||..|||.::....|   .||:    .||..:|||:..:..:
  Fly  1525 AVNVASRMDSTGLPNRIQVGKDCLPFLTNRYEFE----PRGSVYVKGKDHMEVF 1574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	AC_N	<33..285	CDD:292831	63/292 (22%)
		CYCc	293..468	CDD:214485	77/220 (35%)
		Nucleotidyl_cyc_III	307..466	CDD:299850	70/182 (38%)
		CYCc	833..1060	CDD:214485	81/237 (34%)
		Nucleotidyl_cyc_III	861..1085	CDD:299850	76/234 (32%)
Ac13E	NP_001259575.1	CYCc	302..518	CDD:214485	85/222 (38%)
		Guanylate_cyc	361..535	CDD:278633	70/173 (40%)
		CYCc	1362..1556	CDD:214485	81/240 (34%)
		Guanylate_cyc	1388..1575	CDD:278633	76/233 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453972
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45627
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840