Protein Alignment ACXC and gcy-37

DIOPT Version :9

• Sequence 1: NP_609593.1
• Gene: ACXC / 34689
• FlyBaseID: FBgn0040508
• Length: 1130
• Species: Drosophila melanogaster
• Sequence 2: NP_500171.2
• Gene: gcy-37 / 191658
• WormBaseID: WBGene00001557
• Length: 708
• Species: Caenorhabditis elegans
• Alignment Length: 590
• Identity: 111/590 - (18%)
• Similarity: 215/590 - (36%)
• Gaps: 175/590 - (29%)

  Fly    16 KRLRPCHLDYANERLWEH--SYLREKCKELNLEEEYRYYQVRLMVSNLTIFYVLFIILAMSFLTI 78
            |.:.|.|:.:..:.:.||  .||   .:|..||.     :..|.||:|                :
 Worm   229 KNIFPYHVCFNKQMIIEHIGIYL---LREYGLEN-----KKTLKVSDL----------------M 269

  Fly    79 ELLYVQHYNAVFFNFVIRVVSTILVLTVLSINFCEKFVSRHRWVMIASSVLSVYLVVLTDIVMIS 143
            :|:........:.| |:..::|:.:       |..|..|:...|...||......:||...:|
 Worm   270 QLVQPSDIQLTYKN-VLSYLNTLFI-------FQLKHHSKRNEVQEGSSEAFQQPLVLKGEMM-- 324

  Fly   144 YHFYKNDWPLNTSFDVFTLCMIYMFLPIPSIKGAALLASSVSLIYVAFFMHSLTFNAVYTDRDSF 208
                    |:|....:..:|..:                                  |.|.||..
 Worm   325 --------PINDGNSIIFICSPH----------------------------------VTTVRDIL 347

  Fly   209 GYDVISTDI-LHNLGFNMMGIFFRIMNDTMVRASFLDRHQFIMEETWLRHALLQESI-------- 264
            ...:..:|: :|:...:::     ::|.:.:....|::.   :|||..:...:.|.:
 Worm   348 NLKLYISDMPMHDATRDLV-----MLNQSRICQMELNKK---LEETMKKMKKMTEELEVKKSQTD 404

  Fly   265 -LLDSILPPQIAKPVQEKIKSKITQSENSPDRFQMGPRTTESFMAIQIHPDVSILYADVVNYTHL 328
             ||...:||.||    |.:::..|                   :..|...|.|:::.|:.::..:
 Worm   405 RLLFEFVPPVIA----EALRAAKT-------------------VPAQEFSDCSVIFTDIPDFFTI 446

  Fly   329 TTTLTVGNLVKVLHDLYGRFDIAASNFKVQRIKFLGDCYYCVAGLTTPDPDHAKCCVSLGISMIS 393
            :...:...::.|:.||:.|||......|..::..|.|.|..|.|:...:..|.:..::|.:.::.
 Worm   447 SVNCSPTEIITVVTDLFHRFDRIIEKHKGYKVLSLMDSYLIVGGVPNANQYHCEDSLNLALGLLF 511

  Fly   394 NIQEV---RAERGLDIDMRIGVHSGSLLAGIIGEAKLQFDIWGTDVEIANHLESTGEPGYVHVSG 455
            ..::|   :.||  .:.:|||||.|.::|||:.:.|.:|.:.|..|.:...:.|...||.|.||.
 Worm   512 EAKQVVVPKLER--SVRLRIGVHCGPVVAGIVSQQKPRFCVLGNTVNVTKSICSHSSPGKVLVSN 574

  Fly   456 ----------RTLSMLNPADYTIL-SG--------------------TQKAQSDPVLQYIHTYLL 489
                      :::.:.|...|..| ||                    ..||.:|.:..|...:..
 Worm   575 AVRTMVTKHLKSIFVFNANGYLELQSGKVLTHFLEKNEKCSVWDIVDRDKATNDSIDGYRELHSD 639

  Fly   490 TG-------QVARESFITSIGGVRSSSVLEVKSIDRIRSSRPSQSSMTDEFREEFRNMPV--GGI 545
            .|       .||....|:.:..:.:......|::.|:||           .:.:||.:..  .|:
 Worm   640 NGTEEWQEATVAAYRVISVVDALENKQSRTRKALTRLRS-----------VKRKFRTIQSNDSGV 693

  Fly   546 NLNSP 550
            :::.|
 Worm   694 SVSEP 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	AC_N	<33..285	CDD:292831	45/263 (17%)
		CYCc	293..468	CDD:214485	42/187 (22%)
		Nucleotidyl_cyc_III	307..466	CDD:299850	41/171 (24%)
		CYCc	833..1060	CDD:214485
		Nucleotidyl_cyc_III	861..1085	CDD:299850
gcy-37	NP_500171.2	HNOB	3..165	CDD:285002
		HNOBA	223..419	CDD:285003	49/277 (18%)
		CYCc	400..577	CDD:214485	48/201 (24%)
		Nucleotidyl_cyc_III	425..609	CDD:299850	45/185 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810