Protein Alignment ACXC and gcy-20

DIOPT Version :10

• Sequence 1: NP_609593.1
• Gene: ACXC / 34689
• FlyBaseID: FBgn0040508
• Length: 1130
• Species: Drosophila melanogaster
• Sequence 2: NP_507101.1
• Gene: gcy-20 / 184797
• WormBaseID: WBGene00001545
• Length: 1108
• Species: Caenorhabditis elegans
• Alignment Length: 323
• Identity: 84/323 - (26%)
• Similarity: 151/323 - (46%)
• Gaps: 50/323 - (15%)

  Fly   239 RASFLDRHQFIMEETWLRHALLQESILLDSILPPQIAKPVQEKIKSKITQSENSP----DRFQMG 299
            |.:.|..|.|.|.||:.  :.|:|.:      ..:..:..:||.||.:......|    |:.::|
 Worm   808 RKTNLMDHVFNMLETYA--STLEEEV------SDRTKELTEEKKKSDVLLYRMLPRMVADKLKLG 864

  Fly   300 ----PRTTESFMAIQIHPDVSILYADVVNYTHLTTTLTVGNLVKVLHDLYGRFDIAASNFKVQRI 360
                |.|.|         .|:|.::|||.:|.|....|...:|.:|:|||..||.......|.::
 Worm   865 QTVEPETFE---------QVTIFFSDVVQFTTLAGKCTPLQVVTLLNDLYTIFDGIIEQNDVYKV 920

  Fly   361 KFLGDCYYCVAGLTTPD-PDHAKCCVSLGISMISN-----IQEVRAERGLDIDMRIGVHSGSLLA 419
            :.:||.|.||:||...: .||.:....:.:..:|:     :|.:.|||   |::|||::.||::|
 Worm   921 ETIGDGYLCVSGLPHRNGNDHIRHIARMSLGFLSSLEFFRVQHLPAER---INLRIGINCGSVVA 982

  Fly   420 GIIGEAKLQFDIWGTDVEIANHLESTGEPGYVHVSGRTLSMLNPADYTILSGTQ-KAQSDPVLQ- 482
            |::|....::.::|..|..|:.:||.|:||.:||:.....||.    .::.|.: :::.:.:::
 Worm   983 GVVGLTMPRYCLFGDAVNTASRMESNGKPGQIHVTAEANRMLT----QVVGGFRTESRGEVIIKG 1043

  Fly   483 --YIHTYLLTGQ--------VARESFITSIGGVRSSSVLEVKSIDRIRSSRPSQSSMTDEFRE 535
              .:.|:.|.|:        .|....|.....:||.|.:..|:.:...:|..|.....|...|
 Worm  1044 KGVMETFWLLGEESGYTAPSKAAPKVIQHRQSIRSISPILEKNAEGSETSSLSVDQAGDNNSE 1106

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	Nucleotidyl_cyc_III	307..466	CDD:448371	51/164 (31%)
		Nucleotidyl_cyc_III	861..1085	CDD:448371
gcy-20	NP_507101.1	PBP1_NPR_GC-like	22..427	CDD:380575
		Protein Kinases, catalytic domain	536..801	CDD:473864
		HNOBA	<817..861	CDD:462234	12/51 (24%)
		CYCc	840..1032	CDD:214485	62/207 (30%)