Protein Alignment ACXC and acy-3

DIOPT Version :9

• Sequence 1: NP_609593.1
• Gene: ACXC / 34689
• FlyBaseID: FBgn0040508
• Length: 1130
• Species: Drosophila melanogaster
• Sequence 2: NP_497765.4
• Gene: acy-3 / 175489
• WormBaseID: WBGene00000070
• Length: 1243
• Species: Caenorhabditis elegans
• Alignment Length: 1150
• Identity: 238/1150 - (20%)
• Similarity: 446/1150 - (38%)
• Gaps: 279/1150 - (24%)

  Fly    48 EYRYYQVRLMVSNLTIFYVLFIILAMSFLTIELLYVQHYNAVFFNFVIRVVSTILVLTVLSINFC 112
            |..|...|...|...|..||||....:||. .|.::..:.|::       .:.||:|:.::|.|
 Worm     9 EQSYLDWRHAASARLIRIVLFITSGSAFLR-TLGHIPGFYALW-------TAVILLLSTVTIIF- 64

  Fly   113 EKFVSRH--RWVMIASSVLSVYLVVLTDIVMISYHFYKNDWPLNTSFDVFTLCMIYMFLPIPSIK 175
                  |  |...||:..:...:|:|.| |..:...|::.:|  ....||:|   |.|..:|..
 Worm    65 ------HILRPARIAAFQILAGIVLLLD-VAFALPGYESLFP--ALLAVFSL---YTFFSLPFY- 116

  Fly   176 GAALLASS--VSLIYVAFFMHSLTFNAVYTDRDSFGYDVISTDILHNLGFNMMGIFFRIMNDTMV 238
              |:||:|  :|::....|:  |....::|:      ::::..::| :..|..||:.....|.:.
 Worm   117 --AILATSTLISIVQTCSFL--LFVEPLHTN------ELLAIIVVH-IWTNFTGIYLCSTADRLA 170

  Fly   239 RASFLDRHQFIMEETWLRHALLQESILLDSILPPQIAKPVQEKIKSKITQSENSPDRFQMGPRTT 303
            |.:||........|:.......:.:.||.|.||..:....:.:|      :...|..:.
 Worm   171 RNAFLSARNSSEAESTAEFQSNRLNKLLSSFLPYHLINQARHQI------TLYKPHLYN------ 223

  Fly   304 ESFMAIQIHPDVSILYADVVNYTHLTTTLTVGNLVKVLHDLYGRFD-IAASNFKVQRIKFLGDCY 367
                  :.:..||:.|..:|.:..:....:..:..:||.:|..|.: :|||| ...|:...|...
 Worm   224 ------ETYSQVSVAYGRLVGFESVLAQCSSIDAARVLKELDSRIERLAASN-GCTRVASEGITA 281

  Fly   368 YC-VAGLTTPDPDHAKCCVSLGISMISNIQEVRAERGLDIDMRIGVHSGSLLAGIIGEAKLQFDI 431
            .| :.|:   |..||.......:.:.:.|...|...|.|:.:.||:.||.:.||::|.:|..:|:
 Worm   282 VCSIPGI---DSQHATKLCRFSMELETLINSFRDATGADVSVCIGIDSGPVTAGVVGVSKWHYDV 343

  Fly   432 WGTDVEIANHLESTG-EPGYVHVSGRTLSMLNPADYTILSGTQKAQSDPVLQYIHTYLLTGQVAR 495
            .|:..:.|..::|.. ||| |:||..|...|..      :|..:.:..|:...::.:|    .:.
 Worm   344 IGSVFDNALLMQSNATEPG-VYVSNETRRFLGS------TGEFELEKCPIGWKLYGHL----PSP 397

  Fly   496 ESFITSIGGVRSSSVLEVKSIDRIRSS----RPSQSSM-TDEFREEFRNMPVGGINLNSPCCRRT 555
            |.|..:   .|.|.|...::::|:..|    .|:..:| |::.|:..::              :.
 Worm   398 ELFPVN---KRFSLVTVPQAVNRVLQSIVAMNPTLKTMGTNKKRKGEKS--------------QE 445

  Fly   556 RLDTHKKTQRE---IGIFCAAFKDSSLEWNYLHQPDFIFKSSM------LLAWGIGCCLIYIQIV 611
            :.|..||....   |......|::..||..|..:.|..|..|:      |:.:||...|:..:::
 Worm   446 KFDMQKKKVEHSTIISTLSQRFRNPGLEAEYHKETDHWFIPSLAISIFFLVVYGIYHMLVMPRLI 510

  Fly   612 TNNFSCTACIVVDLVTFFFLTSLLCLAWYKNVCWWKSGRYEFRIYGKYSCMAFHIFEKI------ 670
            |:    .|.||..|...||:..:|.:.:                        ||.|.:.
 Worm   511 TS----LALIVGALTVMFFILLMLYIDY------------------------FHTFSQFITRTSA 547

  Fly   671 QHSVSLRITVYLGILFSYYAVISLI-MLNCDR----DMYELSYIESKIYHYEMDRDTCFHPWVFT 730
            .|:||  |.:.:.|||    |..:: ..:|.:    |:.:.::..:  |.:.|        |..|
 Worm   548 GHAVS--IILIIVILF----VCGIVNTFSCPQPNAPDVCQKAHFST--YSFAM--------WTIT 596

  Fly   731 NMISLILGISYTFARIPFGLKIVISCCETLAYLLIVFFQFAFIFQHSATTTP-------FMKAEL 788
            ..:         |.|.|.....::.....|.|.|.::           .|.|       ||....
 Worm   597 TAV---------FVRFPSVYLAILLIISLLTYGLQIY-----------VTRPDEFGPREFMTELD 641

  Fly   789 AHCLRVCMMLLTMYAKERQSEFNTKMNYKLNV----DLQNKQKAADLTNQSIIILLNNILPSHVV 849
            ..|..:.::.: ::...|:.|...::::...|    :...|.|..:|.||    :|.|::|:||.
 Worm   642 LSCFLISLVSM-VFLHSRRCERLLRLDFLAVVKGIEETSMKDKLINLNNQ----MLLNLVPAHVA 701

  Fly   850 DLYLNSLAKHELYYENYRMVSVMFAMLINFPM-NLPSLRVLNDIITQFDRLLTAYREYYVVEKIK 913
            ...:....  ::::.:::.|.:.:..:..|.: ....:..||.:.:.||:.:..|:.   |||:|
 Worm   702 PGVIQKAG--DVWHHSHQSVGIAYIAVSGFDLEGEAGINGLNYVFSHFDQAIANYKG---VEKVK 761

  Fly   914 VVGCTYMAACGLDFNLASNIRQTDHFRNSSLHVEVEHARNHRMTDENYDSDMNNDEVVFIMTTFA 978
            .....|:.|.||..:.|.|:.:|.                                     .|..
 Worm   762 SANRFYIVAVGLLPDAAQNVNETP-------------------------------------WTIG 789

  Fly   979 LDLMRTLAACNRAYSSSFFERSLSQ------GKICIGISSGEIMAGVVGASQPHYDIWGNPVNMA 1037
             :||.|||         .|..|:||      ..:.||:..|..:|.|....||.|:|:|..::.:
 Worm   790 -ELMSTLA---------HFIISISQFAMENEFHVQIGVDCGSTLAFVANTDQPRYEIFGETLDRS 844

  Fly  1038 -SRMESTG--------------LPGHIQVTEESAKILQEFDIKCIYRGMTFVKGRGDIPTYFVGI 1087
             :.|::.|              .|..::.:.:..|:....:...:..|:..|.  .||||  :..
 Worm   845 RTLMQAAGHDTTLVSEEVFLALRPRPLRFSSQPVKVAMNLNAYELVTGLRDVS--VDIPT--MPR 905

  Fly  1088 DENLK----FMSAKLVNRSLSRRFSVMSSLDPDSLRKSSSSDQES 1128
            :|..:    .:.|:..|:  ||.:...:|....|:..|.||:..|
 Worm   906 EEQERHTQGMVEAQFANQ--SRMYDTQTSEMASSMASSFSSELRS 948

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	AC_N	<33..285	CDD:292831	57/240 (24%)
		CYCc	293..468	CDD:214485	44/177 (25%)
		Nucleotidyl_cyc_III	307..466	CDD:299850	43/161 (27%)
		CYCc	833..1060	CDD:214485	49/248 (20%)
		Nucleotidyl_cyc_III	861..1085	CDD:299850	48/245 (20%)
acy-3	NP_497765.4	TctB	26..137	CDD:284693	36/136 (26%)
		CYCc	195..378	CDD:214485	50/211 (24%)
		Nucleotidyl_cyc_III	221..382	CDD:299850	44/183 (24%)
		CYCc	696..873	CDD:214485	44/228 (19%)
		Nucleotidyl_cyc_III	711..880	CDD:299850	41/218 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810