Protein Alignment ACXC and Gucy2e

DIOPT Version :9

• Sequence 1: NP_609593.1
• Gene: ACXC / 34689
• FlyBaseID: FBgn0040508
• Length: 1130
• Species: Drosophila melanogaster
• Sequence 2: XP_036012232.1
• Gene: Gucy2e / 14919
• MGIID: 105123
• Length: 1139
• Species: Mus musculus
• Alignment Length: 547
• Identity: 117/547 - (21%)
• Similarity: 200/547 - (36%)
• Gaps: 194/547 - (35%)

  Fly   663 AFHIFEKIQHSVSLRITVYLGILFSYYA---------VISLIMLNCDR-DMYELSYIESKIYHYE 717
            ||....:::|.   .:.:|||:..:..|         :::::..:|.| .:::|      :...|
Mouse   614 AFSKLRELRHE---NVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDL------LAQRE 669

  Fly   718 MDRDTCFHPWVFTN--MISLILGISYTFAR-IPFGLKIVISCCETLAYLLIV------------- 766
            :..|     |:|.:  ::.||.|:.|...| :..|.....:|.....::|.|
Mouse   670 IKLD-----WMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQR 729

  Fly   767 ---------------------------------FFQFAFIFQH-SATTTPFMKAELAH------- 790
                                             .|..|.|.|. ...:||:...||..
Mouse   730 VLPEPPSAEDQLWTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCRSTPYAMLELTPEEVIQRV 794

  Fly   791 ------CLRV---------CMMLLTM---------------------YAKERQSEFNTKM----- 814
                  |..:         |:.|:|.                     ..|.|::.....|
Mouse   795 RSPPPLCRPLVSMDQAPMECIQLMTQCWAEHPELRPSMDLTFDLFKSINKGRKTNIIDSMLRMLE 859

  Fly   815 NYKLNVD--LQNKQKAADLTNQSIIILLNNILPSHVVDLYLNSLAKHELYYENYRMVSVMFAMLI 877
            .|..|::  ::.:.:..:...|....||..:||..|.:......:....|:|.   |::.|:.::
Mouse   860 QYSSNLEDLIRERTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEE---VTLYFSDIV 921

  Fly   878 NF--------PMNLPSLRVLNDIITQFDRLLTAYREYYVVEKIKVVGCTYMAACGLDFNLASNIR 934
            .|        |:.:..|  |||:.|.||.::.|:..|    |::.:|..||.|.||.
Mouse   922 GFTTISAMSEPIEVVDL--LNDLYTLFDAIIGAHDVY----KVETIGDAYMVASGLP-------- 972

  Fly   935 QTDHFRNSSLHVEVEHARNHRMTDENYDSDMNNDEVVFIMTTFALDLMRTLAACNRAYSSSFFER 999
                .||...|.                :::.|         .:||::..:        .||..|
Mouse   973 ----QRNGQRHA----------------AEIAN---------MSLDILSAV--------GSFRMR 1000

  Fly  1000 SLSQ--GKICIGISSGEIMAGVVGASQPHYDIWGNPVNMASRMESTGLPGHIQVTEESAKIL--- 1059
            .:.:  .:|.||:.||..:|||||.:.|.|.::|:.||.||||||||||..|.|...:.:||
Mouse  1001 HMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNMSTVRILRAL 1065

  Fly  1060 -QEFDIKCIYRGMTFVKGRGDIPTYFV 1085
             |.|.::|  ||.|.:||:|...||::
Mouse  1066 DQGFQMEC--RGRTELKGKGIEDTYWL 1090

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	AC_N	<33..285	CDD:292831
		CYCc	293..468	CDD:214485
		Nucleotidyl_cyc_III	307..466	CDD:299850
		CYCc	833..1060	CDD:214485	66/240 (28%)
		Nucleotidyl_cyc_III	861..1085	CDD:299850	71/237 (30%)
Gucy2e	XP_036012232.1	PBP1_sensory_GC_DEF-like	58..465	CDD:380594
		PK_GC-2D	570..845	CDD:270945	35/244 (14%)
		HNOBA	<854..899	CDD:400168	9/44 (20%)
		CYCc	879..1070	CDD:214485	67/244 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810