DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ACXC and gc2

DIOPT Version :9

Sequence 1:	NP_609593.1	Gene:	ACXC / 34689	FlyBaseID:	FBgn0040508	Length:	1130	Species:	Drosophila melanogaster
Sequence 2:	XP_021333059.1	Gene:	gc2 / 140425	ZFINID:	ZDB-GENE-011128-8	Length:	1120	Species:	Danio rerio

Alignment Length:	332	Identity:	82/332 - (24%)
Similarity:	149/332 - (44%)	Gaps:	77/332 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 DTMVRASFLDRHQFIMEETWLRHALLQESI------------LLDSILPPQIAKPVQEKIKSKIT 287
            |:|:|  .|:::...:||      |::|..            ||..:|||.:|    |.:|...|
Zfish   822 DSMLR--MLEQYSSNLEE------LIRERTEELEIEKQKTEKLLTQMLPPSVA----EALKLGTT 874

  Fly   288 QSENSPDRFQMGPRTTESFMAIQIHPDVSILYADVVNYTHLTTTLTVGNLVKVLHDLYGRFDIAA 352
            .   .|:.|:                .||:.::|:|.:|.::.......:|.:|:|||..||...
Zfish   875 V---EPEHFE----------------SVSLYFSDIVGFTTISANSEPIEVVDLLNDLYTTFDAVI 920

  Fly   353 SNFKVQRIKFLGDCYYCVAGLTTPDPD-HAKCCVSLGISMISNIQEVRAERGLDID--MRIGVHS 414
            .|..|.:::.:||.|...:|:..|:.: ||....::.:.::|.:...|.....|:.  :|||:|:
Zfish   921 GNHDVYKVETIGDAYMVASGVPVPNGNRHAAEIANMALDILSAVGTFRMRHMPDVPVRIRIGLHT 985

  Fly   415 GSLLAGIIGEAKLQFDIWGTDVEIANHLESTGEPGYVHVSGRTLSMLNPADY---------TILS 470
            |..:||::|....::.::|..|..|:.:||||.|..:||...|:.:|.....         |.|.
Zfish   986 GPCVAGVVGLTMPRYCLFGDTVTTASRMESTGLPYRIHVHSSTVKILMELKLGYRVELRARTELK 1050

  Fly   471 GTQKAQSDPVLQYIHTYLLTGQVARESFITSI-------GGVRSS--SVLEVKSIDRIRSSRP-S 525
            |.:..:         ||.|||   |:.|...:       .|:.|.  .|:..|::.:|.:.|. :
Zfish  1051 GKRIEE---------TYWLTG---RDGFTKPLPVPPVLKSGLESKDFKVMLKKAVRKISTVRQVA 1103

  Fly   526 QSSMTDE 532
            |.:::||
Zfish  1104 QLTLSDE 1110

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	AC_N	<33..285	CDD:292831	16/61 (26%)
		CYCc	293..468	CDD:214485	46/186 (25%)
		Nucleotidyl_cyc_III	307..466	CDD:299850	44/161 (27%)
		CYCc	833..1060	CDD:214485
		Nucleotidyl_cyc_III	861..1085	CDD:299850
gc2	XP_021333059.1	PBP1_sensory_GC_DEF_like	59..440	CDD:107366
		PK_GC-2D	551..815	CDD:270945
		HNOBA	<824..869	CDD:311573	14/56 (25%)
		CYCc	848..1040	CDD:214485	55/214 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810