Protein Alignment ACXC and LOC1272957

DIOPT Version :10

• Sequence 1: NP_609593.1
• Gene: ACXC / 34689
• FlyBaseID: FBgn0040508
• Length: 1130
• Species: Drosophila melanogaster
• Sequence 2: XP_061519369.1
• Gene: LOC1272957 / 1272957
• VectorBaseID: AGAMI1_006876
• Length: 1413
• Species: Anopheles gambiae
• Alignment Length: 1096
• Identity: 294/1096 - (26%)
• Similarity: 491/1096 - (44%)
• Gaps: 243/1096 - (22%)

  Fly    56 LMVSNLTIFYVLFIILAMSFLTIELLYVQHYNAVFFNFVIRVVSTILVLTVLSINFC-------E 113
            |:..|:|...||.:...:..|.:..||.|..|.::    :..||.::::|:|.::.|       :
Mosquito   486 LLKDNMTQIIVLGVCATVYALLLMCLYKQRINEIY----LFQVSYVIMVTLLVLDVCFSFTTSAK 546

  Fly   114 KFVSRHRWVMIASSVLSVYLVVLTDIVMISYHFYKNDWPLNTSFDVFTLCMIYMFLPI---PSIK 175
            ||.|..     ..:|:::|:                               ||..|||   .::.
Mosquito   547 KFTSSG-----GCTVIAIYI-------------------------------IYTMLPIRLREAVV 575

  Fly   176 GAALLASSVSLIYVAFFMHSLTFNAVYTDRDSFGYDVISTDILHNLGFNMMGIFFRIMNDTMVRA 240
            |.:||  |:|.|.:.|:|:           :|...||:..|::.....|..||......:...|.
Mosquito   576 GGSLL--SISHIALMFYMN-----------ESDDMDVLYCDLITLACTNATGILLHWPKEKSQRK 627

  Fly   241 SFLDRHQFIMEETWLRHALLQESILLDSILPPQIAKPVQEKIKSKITQSENSPDRFQMGPRTTES 305
            :|::..|.:.....::....::..||.|:||..:|..::..|..:              ||..:.
Mosquito   628 AFMETRQCVEARLKIQRENQKQEQLLLSVLPRHVAMEMKNDIAGQ--------------PREAQF 678

  Fly   306 F-MAIQIHPDVSILYADVVNYTHLTTTLTVGNLVKVLHDLYGRFDIAASNFKVQRIKFLGDCYYC 369
            . :.||.|.:||||:||:..:|.|:...|...||::|::|:.|||..|......|||.|||||||
Mosquito   679 HKIYIQRHENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAQEHHCLRIKLLGDCYYC 743

  Fly   370 VAGLTTPDPDHAKCCVSLGISMISNIQEVRAERGLDIDMRIGVHSGSLLAGIIGEAKLQFDIWGT 434
            |:||....||||.|.|.:|:.||..|..||....::::||:|:|:|.:..|::|..|.|||:|..
Mosquito   744 VSGLPEARPDHALCAVEMGLDMIDAIALVREVMAVNVNMRVGIHTGRVHCGVLGLRKWQFDVWSN 808

  Fly   435 DVEIANHLESTGEPGYVHVSGRTLSMLNPADYTILSGTQKAQSDPVLQ--YIHTYLLTGQ----- 492
            ||.:||::||.|.||.||::..||..|.. .|.:..| :.|..:..|:  .|.|||:..:
Mosquito   809 DVTLANYMESGGVPGRVHITKETLRCLGD-HYDVEEG-RGADRNSYLKDHQIQTYLIVPKDASYR 871

  Fly   493 ---VARESFITSIGGVRSSSVLEVKSIDRIRSSRPSQSSMTDEFREEFRNMPVGGINLNSPCCRR 554
               ::::|  :|:.|..|..:..:....::..:..::...|:|...|:....:...:::     |
Mosquito   872 PHTMSKQS--SSVNGNISKELRMMGHWSKMGFNDKTEPKSTEEEVNEYLIKAIDARSID-----R 929

  Fly   555 TRLDTHKKTQREIGIFCAAFKDSSLEWNYLHQPD----FIFKSSMLLAWGIGCCLIYIQIVTNNF 615
            .|||..|:       |...|....:|..|..:||    ..|..|:::..||    :.||::..:.
Mosquito   930 LRLDHCKR-------FHLTFIKDEIERKYCLEPDPMLNVYFYCSIIIFLGI----MSIQVLVFSM 983

  Fly   616 SCTACIVVDLVTFFFLTSLLCLAWYKNVCWWKSGRYEFRIYGKYSCMA--FHIFEKIQHSVSLRI 678
            ...:..|..:::...|.|  |:..:.        |.:.::...:..::  .|...:|...:||.:
Mosquito   984 DHYSYWVYGILSLTLLVS--CVPVFT--------REDMKVSTFFRALSQKIHGHREIAQVISLCV 1038

  Fly   679 TVYLGILFSYYAVISLIML------------NCDRDMYELSYIESKIYHYEMDRDTCFHPWVFTN 731
            .:.: |..|||.:..:..|            ||.         ||||.:.          .:...
Mosquito  1039 VITV-ICLSYYKLTLIFYLSLYDEFPLVRPSNCK---------ESKIINI----------LLLLT 1083

  Fly   732 MISLILGISYTFARIPFGLKIVISCCETLAYLLIVFFQ----FAFIFQHSA-----TTTPFMKAE 787
            :::|:....:.|.:|.|  ||::     |..:|:::..    .|.||:...     ||..|: .:
Mosquito  1084 LLALLTCAVHQFIKILF--KILL-----LIVILVLYIASIIVLALIFERHCEPWFLTTERFL-ID 1140

  Fly   788 LAHCLRVCMMLLTMYAKERQSEFNTKMNYKLNVDLQNKQKAADLT-----NQSIIILLNNILPSH 847
            :|.   :.:.::......:|:|...::::...  ||..::..|:.     |:.   ||.||||.|
Mosquito  1141 VAF---LVVFVIGQIMHSQQTEITRRLDFIWK--LQATEEKEDMEHLQAYNRK---LLANILPVH 1197

  Fly   848 VVDLYL-NSLAKHELYYENYRMVSVMFAMLINFP----------MNLPSLRVLNDIITQFDRLLT 901
            |.|.:| ......|:|:|....|.||||.:.||.          ..:..||:||:||..||.||.
Mosquito  1198 VADHFLMREKNIEEIYHEQCDTVCVMFASIPNFSEFYIELEGNNEGVECLRLLNEIIVDFDELLG 1262

  Fly   902 AYREYYVVEKIKVVGCTYMAACGLDFNLASNIRQTDHFRNSSLHVEVEHARNHRMTDENYDSDMN 966
            ..|..| |||||..|.|||||.||..|                                 ..|.|
Mosquito  1263 LERFRY-VEKIKTTGSTYMAASGLTAN---------------------------------SCDKN 1293

  Fly   967 NDEVVFIMTTFALDLMRTLAACNRAYSSSFFERSLSQGKICIGISSGEIMAGVVGASQPHYDIWG 1031
            :.:.||.|..:||:|.:.:...|        |.|.:..::.|||:.|.::|||:|..:|.|||||
Mosquito  1294 DFQHVFAMMDYALELFQKITDVN--------EHSFNNFRMRIGINIGPVVAGVIGTRKPQYDIWG 1350

  Fly  1032 NPVNMASRMESTGLPGHIQVTEESAKILQE--FDIKCIYRGMTFVKGRGDIPTYFV 1085
            |.||:||||:||||..||||||:..:|:::  :::.|  ||...|||:|.:.||.:
Mosquito  1351 NAVNVASRMDSTGLMDHIQVTEDVYQIVKDKGYNLTC--RGTVNVKGKGTMITYLM 1404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	Nucleotidyl_cyc_III	307..466	CDD:448371	71/158 (45%)
		Nucleotidyl_cyc_III	861..1085	CDD:448371	87/235 (37%)
LOC1272957	XP_061519369.1	None