Protein Alignment ACXC and Npr2

DIOPT Version :10

• Sequence 1: NP_609593.1
• Gene: ACXC / 34689
• FlyBaseID: FBgn0040508
• Length: 1130
• Species: Drosophila melanogaster
• Sequence 2: NP_446290.1
• Gene: Npr2 / 116564
• RGDID: 620851
• Length: 1047
• Species: Rattus norvegicus
• Alignment Length: 485
• Identity: 103/485 - (21%)
• Similarity: 197/485 - (40%)
• Gaps: 132/485 - (27%)

  Fly    76 LTIELLY-VQHYNAVFFNFVIRVVSTIL-------------------VLTVLSINFCEKF----- 115
            ||.::|: ::|...|.||.:.|.:...:                   :|...|||....|
  Rat   560 LTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLI 624

  Fly   116 --------------VSRHRWVMIASSVL-SVYLVVLTDIVMISYH-----------FYKNDW--- 151
                          :|.|..:..::.|: |.:::.:||..:.|:.           :.|..|
  Rat   625 NDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLWTAP 689

  Fly   152 ------PLNTS----FDVFTLCMIYMFLPIPS----IKGAAL----LASSVSLIYVAFFMHSLTF 198
                  ||.|:    .||::..:|...:.:.|    ::|..|    :...|......:|..|:
  Rat   690 ELLSGNPLPTTGMQKADVYSFAIILQEIALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSI-- 752

  Fly   199 NAVYTDRDSFGYDVI-------STDILHNLGFNMMGIFFR---------IMNDTMVR-ASFLDRH 246
                 ||.....:::       :.|......|..:..|.|         |:::.::| ..:.:..
  Rat   753 -----DRTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNL 812

  Fly   247 QFIMEETWLRHALLQE----SILLDSILPPQIAKPVQEKIKSKITQSENSPDRFQMGPRTTESFM 307
            :.::||.  ..|.|:|    ..||..|||..:|:.::   :.:..|:|
  Rat   813 EKLVEER--TQAYLEEKRKAEALLYQILPHSVAEQLK---RGETVQAE----------------- 855

  Fly   308 AIQIHPDVSILYADVVNYTHLTTTLTVGNLVKVLHDLYGRFDIAASNFKVQRIKFLGDCYYCVAG 372
               ....|:|.::|:|.:|.|:...|...:|.:|:|||..||....||.|.:::.:||.|..|:|
  Rat   856 ---AFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSG 917

  Fly   373 LTTPD-----PDHAKCCVSLGISMISNIQEVRAERGLDIDMRIGVHSGSLLAGIIGEAKLQFDIW 432
            |...:     |:.|:..::| :..:|:.: :|......:.:|||||:|.:.||::|....::.::
  Rat   918 LPGRNGQRHAPEIARMALAL-LDAVSSFR-IRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLF 980

  Fly   433 GTDVEIANHLESTGEPGYVHVSGRTLSMLN 462
            |..|..|:.:||.|:...:|||..|...|:
  Rat   981 GDTVNTASRMESNGQALKIHVSSTTKDALD 1010

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	Nucleotidyl_cyc_III	307..466	CDD:448371	48/161 (30%)
		Nucleotidyl_cyc_III	861..1085	CDD:448371
Npr2	NP_446290.1	PBP1_NPR_B	26..421	CDD:380607
		PK_GC-A_B	518..792	CDD:270944	40/238 (17%)
		HNOBA	<798..846	CDD:462234	12/49 (24%)
		CYCc	825..1009	CDD:214485	56/208 (27%)