Protein Alignment ACXC and adcy6

DIOPT Version :9

• Sequence 1: NP_609593.1
• Gene: ACXC / 34689
• FlyBaseID: FBgn0040508
• Length: 1130
• Species: Drosophila melanogaster
• Sequence 2: XP_002935166.2
• Gene: adcy6 / 100493933
• XenbaseID: XB-GENE-1011902
• Length: 1239
• Species: Xenopus tropicalis
• Alignment Length: 1156
• Identity: 304/1156 - (26%)
• Similarity: 508/1156 - (43%)
• Gaps: 232/1156 - (20%)

  Fly    38 EKCKELNLEEEYRYYQVRLMVSNLTIFYVLFIILAMSFLTI-------ELLYVQHYNAVFFNFVI 95
            :|.:...||..|:.|..::..|:||:.....:::.:..|..       :::||.          :
 Frog   201 KKFQSAKLERLYQRYFFQMNQSSLTMLMGALVLVCLVMLIFHCTHGEPQVVYVS----------V 255

  Fly    96 RVVSTILVLTVLSINFCEK--FVSRHRWVMIASSVLSVYLVVLTDIVMISYHFYKNDWPLNTS-- 156
            ..|:..|.|:::.:  |.:  |...:.|::....:..::.|.:..::|::        |.:.|
 Frog   256 LAVAMALFLSLMVV--CNRNGFHQDYMWIVSYLVIAVLFAVQVLGVLMVT--------PRSASEG 310

  Fly   157 --FDVFTLCMIYMFLPIPSIKGA---ALLASSVSLIYVAFFMHSLTFNAVYTDRDSFGYDVISTD 216
              :.||.:.:||..||: .::.|   .|:.||:.||.      |...|..    |.|.:..:|.:
 Frog   311 IWWSVFFIYIIYTLLPV-RMRAAVLSGLILSSLHLII------SWRLNLT----DIFLWKQLSAN 364

  Fly   217 ILHNLGFNMMGIFFRIMNDTMVRASFLDRHQFIMEETWLRHALLQESILLDSILPPQIAKPVQEK 281
            :|..|..|::||......:...|.:|.:...:|.....|:....|:..||.|:||..:|..::|.
 Frog   365 VLIFLCTNIIGICTHYPAEVSQRQAFQETRGYIQARLHLQRENQQQERLLLSVLPRHVAMEMKED 429

  Fly   282 IKSKITQSENSPDRFQMGPRTTESFM----AIQIHPDVSILYADVVNYTHLTTTLTVGNLVKVLH 342
            |.:|                 .|..|    .||.|.:||||:||:..:|.|.:..|...||..|:
 Frog   430 INTK-----------------KEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLN 477

  Fly   343 DLYGRFDIAASNFKVQRIKFLGDCYYCVAGLTTPDPDHAKCCVSLGISMISNIQEVRAERGLDID 407
            :|:.|||..|:.....|||.||||||||:||.....|||.|||.:|:.||..|..||...|::::
 Frog   478 ELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVN 542

  Fly   408 MRIGVHSGSLLAGIIGEAKLQFDIWGTDVEIANHLESTGEPGYVHVSGRTLSMLNPADYTILSGT 472
            ||:|:|||.:..|::|..|.|||:|..||.:|||:|:.|:.|.:|::..||..|| .||.:..|.
 Frog   543 MRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITSATLKYLN-GDYEVEPGN 606

  Fly   473 QKAQSDPVLQY-IHTYLLTG--QVARE--SFITSIGGVRSSS--------VLEVKSIDRIRSSRP 524
            ...::..:.:: |.|:|:||  |..:|  :.:..:...|::|        |.| :|..|.:.|:.
 Frog   607 GGERNAYLKEHDIKTFLVTGCSQKRKEEKAMMARLQRARANSNEGLTRVWVPE-RSFPRNKGSKA 670

  Fly   525 SQSSMTDEFREEFRNM-----PVGGIN------LNSPCCRRTRLDTHKKTQREIGIFCAAFKDSS 578
            .:....||..::.||.     |...::      :::....:.|.|..||       |...|:...
 Frog   671 FRQMGIDESSKDNRNTQEALNPEDEVDEFLARAIDARSIDQLRKDHVKK-------FLLTFQTPD 728

  Fly   579 LEWNYLHQPDFIFKSSMLLAWGIGCCLIYIQIVTNNFSCTACIVVDLVTFFFLTSLLCLAWYKNV 643
            ||..|..:.|..|...:.....:.|.:.:||||....|.....|...| |..|.|:|.      |
 Frog   729 LEKKYSKKVDDRFGGYVTCTLLVFCFICFIQIVIFPHSFLMLGVYTSV-FIILASILF------V 786

  Fly   644 CWWKSGRYEFRIYGKYSCMAFHIFEKIQHSVSLRI------TVYLGIL----------FSYYAVI 692
            |            ..|||:  .:|......||.:|      :..:|||          .:.:|..
 Frog   787 C------------AIYSCI--KLFPAALQGVSRKIVQSRTNSTLIGILTILLVFTSAFVNMFACN 837

  Fly   693 SLIMLNCDRDMYELSYIESKIYHYEM--------------DRDTCFHPWVFTNMISLILGISYTF 743
            ...:.:|......:||....:.|..|              |:..|..|..|...|.|.|.....|
 Frog   838 HRSLTDCAGQELNISYKFVNVCHLRMLNYSLSMDSPPCDSDKPLCNFPEYFNYSILLSLLACSVF 902

  Fly   744 ARIPFGLKIVISCCETLAYLLIVFFQFAFIFQH-----SATTTPFM-KAELAHCLR--------- 793
            .:|....|:.:.....:.|::||......:|.:     :....|.. ..::..||.
 Frog   903 LQISSIGKLALMLFIQILYIVIVEGPEVVLFDNYDLLVTVNALPINGTGDIEECLPSSKIALKFV 967

  Fly   794 ----VCMMLLTMYAKERQSEFNTKMNYKLNVDLQNKQKAADLTNQSIIILLNNILPSHVVDLYLN 854
                :.:.:|.:|...:|.|...::::...:....:::..:........||:||||..|...:|
 Frog   968 TPVILTVFVLALYLHAQQVESTARLDFLWKLQATGEKEEMEQLQAYNRRLLHNILPKDVAAHFL- 1031

  Fly   855 SLAKH---ELYYENYRMVSVMFAMLINFP----------MNLPSLRVLNDIITQFDRLLTAYREY 906
             ..:|   ||||::...|:||||.:.||.          ..:..||:||:||..||.:::. .::
 Frog  1032 -AREHRNDELYYQSCECVAVMFASICNFSEFYVELEANNEGVECLRLLNEIIADFDEIISE-EKF 1094

  Fly   907 YVVEKIKVVGCTYMAACGLDFNLASNIRQTDHFRNSSLHVEVEHARNHRMTDENYDSDMNNDEVV 971
            ..:||||.:|.|||||.||:                               |..||.:....  :
 Frog  1095 KQLEKIKTIGSTYMAASGLN-------------------------------DTTYDKEGKTH--I 1126

  Fly   972 FIMTTFALDLMRTLAACNRAYSSSFFERSLSQGKICIGISSGEIMAGVVGASQPHYDIWGNPVNM 1036
            ..:..:|:.|...:...|        |.|.:..::.||::.|.::|||:||.:|.||||||.||:
 Frog  1127 TALADYAMKLREQMKYIN--------EHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNV 1183

  Fly  1037 ASRMESTGLPGHIQVTEESAKIL--QEFDIKCIYRGMTFVKGRGDIPTYFV 1085
            ||||:|||||..||||.:..::|  :.:.::|  ||:..|||:|::.|||:
 Frog  1184 ASRMDSTGLPDCIQVTTDLYQVLAAKGYQMEC--RGVIKVKGKGEMTTYFL 1232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	AC_N	<33..285	CDD:292831	56/262 (21%)
		CYCc	293..468	CDD:214485	76/178 (43%)
		Nucleotidyl_cyc_III	307..466	CDD:299850	73/162 (45%)
		CYCc	833..1060	CDD:214485	79/241 (33%)
		Nucleotidyl_cyc_III	861..1085	CDD:299850	78/235 (33%)
adcy6	XP_002935166.2	AC_N	89..440	CDD:292831	59/286 (21%)
		CYCc	406..601	CDD:214485	85/212 (40%)
		Guanylate_cyc	442..615	CDD:278633	75/173 (43%)
		DUF1053	656..740	CDD:283888	20/91 (22%)
		PotE	<741..925	CDD:223605	42/204 (21%)
		CYCc	1007..1215	CDD:214485	79/251 (31%)
		Guanylate_cyc	1040..1233	CDD:278633	79/237 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45627
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100