Protein Alignment ACXC and gucy1a2

DIOPT Version :10

• Sequence 1: NP_609593.1
• Gene: ACXC / 34689
• FlyBaseID: FBgn0040508
• Length: 1130
• Species: Drosophila melanogaster
• Sequence 2: NP_001120379.1
• Gene: gucy1a2 / 100145454
• XenbaseID: XB-GENE-1011801
• Length: 712
• Species: Xenopus tropicalis
• Alignment Length: 271
• Identity: 74/271 - (27%)
• Similarity: 132/271 - (48%)
• Gaps: 37/271 - (13%)

  Fly   243 LDRHQFIMEETWLRHALLQES-----ILLDSILPPQIAKPVQEKIKSKITQSENSPDRFQMGPRT 302
            :|:.:..:|:|   |..|:|.     .||.||.|..:|:.:.|   .|..|:.    :|.
 Frog   449 MDKLKATLEKT---HQALEEEKKKTVDLLYSIFPGDVAQQLWE---GKSVQAR----KFD----- 498

  Fly   303 TESFMAIQIHPDVSILYADVVNYTHLTTTLTVGNLVKVLHDLYGRFDIAASNFKVQRIKFLGDCY 367
                       ||::|::|:|.:|.:....|...::.:|::||.|||.......:.:::.:||.|
 Frog   499 -----------DVTMLFSDIVGFTAVCAQCTPMQVISMLNELYTRFDYQCGFLDIYKVETIGDAY 552

  Fly   368 YCVAGLTTPDPDHAKCCVSLGISMISNIQEVRAERGLDIDMRIGVHSGSLLAGIIGEAKLQFDIW 432
            ...|||......|||....:.:.|:...:||....|..|.||||:||||:|||::|....::.::
 Frog   553 CVAAGLLRQSNSHAKPIALMALKMMELSEEVLTPDGRPIKMRIGIHSGSVLAGVVGVRMPRYCLF 617

  Fly   433 GTDVEIANHLESTGEPGYVHVSGRTLSML-NPADYTILSGTQKAQSDPVLQYIH--TYLL---TG 491
            |.:|.:|:..||...|..::||..|..:| :.|::..:..:::...|...:.|.  .|.|   :|
 Frog   618 GNNVTLASKFESGSHPRRINVSPTTYQLLKDEANFHFVPRSREELPDNFPKEIPGICYFLEADSG 682

  Fly   492 QVARESFITSI 502
            |...:..:||:
 Frog   683 QKQPKPSLTSV 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXC	NP_609593.1	Nucleotidyl_cyc_III	307..466	CDD:448371	50/159 (31%)
		Nucleotidyl_cyc_III	861..1085	CDD:448371
gucy1a2	NP_001120379.1	Pap_E4	30..>86	CDD:367150
		HNOB	<137..248	CDD:462233
		HNOBA	296..486	CDD:462234	12/39 (31%)
		Guanylate_cyc	492..679	CDD:425528	56/206 (27%)