DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kek1 and lrrc38b

DIOPT Version :9

Sequence 1:NP_001303320.1 Gene:kek1 / 34688 FlyBaseID:FBgn0015399 Length:880 Species:Drosophila melanogaster
Sequence 2:XP_021335529.1 Gene:lrrc38b / 799882 ZFINID:ZDB-GENE-141216-65 Length:291 Species:Danio rerio


Alignment Length:215 Identity:60/215 - (27%)
Similarity:89/215 - (41%) Gaps:28/215 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    86 QQSTCQTVCACKWKGGKQTVECIDRHLIQIPEHIDPNTQVLDMSGNKLQTLSNEQFIRANLLNLQ 150
            |...|..:|.|.   ...||:|..|.|.::|:.|..:.:.|.::.|.:..:.::..:..:  :|.
Zfish    22 QGENCPAICLCP---DPHTVDCSGRGLTRLPDEIPLDVRRLLLADNWIPRIPSDFLVLYS--DLV 81

  Fly   151 KLYLRNCKIGEIERETFKGLTNLVELDLSHNLLVTVPSLALGHIPSLRELTLASNHIHKIESQAF 215
            .|.|||..:..||..|....:.||.|||..|.|..:|....|...||.:|.|             
Zfish    82 YLDLRNNSLSNIEPGTLSTSSRLVFLDLGCNNLTEIPKGTFGESRSLIKLRL------------- 133

  Fly   216 GNTPSLHKLDLSHCDIQTISAQAFGGLQGLTLLRLNGNKLSELLPKTIETLSRLHGIELHDNPWL 280
            ||.|.|          ..::..||.||..|..|.|..|.||.|....:..|..|..:.|..|||:
Zfish   134 GNNPYL----------SMVNEDAFMGLTSLRELELERNALSGLQVGALSQLPSLRVVRLEGNPWV 188

  Fly   281 CDCRLRDTKLWLMKRNIPYP 300
            |:|...:...||.:.:...|
Zfish   189 CNCNFANLFTWLEENSHKLP 208

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek1NP_001303320.1 leucine-rich repeat 103..122 CDD:275380 7/18 (39%)
LRR_RI <119..277 CDD:238064 42/157 (27%)
leucine-rich repeat 123..148 CDD:275380 2/24 (8%)
LRR_8 148..207 CDD:290566 21/58 (36%)
leucine-rich repeat 149..172 CDD:275380 8/22 (36%)
leucine-rich repeat 173..196 CDD:275380 9/22 (41%)
LRR_8 195..255 CDD:290566 16/59 (27%)
leucine-rich repeat 197..220 CDD:275380 5/22 (23%)
leucine-rich repeat 221..244 CDD:275380 5/22 (23%)
leucine-rich repeat 245..268 CDD:275380 8/22 (36%)
LRRCT 277..327 CDD:214507 8/24 (33%)
IG_like 338..429 CDD:214653
Ig 346..426 CDD:143165
lrrc38bXP_021335529.1 LRRNT 26..56 CDD:214470 10/32 (31%)
leucine-rich repeat 36..58 CDD:275380 7/21 (33%)
PLN00113 <43..>185 CDD:331614 45/166 (27%)
leucine-rich repeat 59..79 CDD:275380 2/21 (10%)
leucine-rich repeat 80..103 CDD:275380 8/22 (36%)
LRR_8 102..163 CDD:316378 25/83 (30%)
leucine-rich repeat 104..127 CDD:275380 9/22 (41%)
leucine-rich repeat 128..152 CDD:275380 11/46 (24%)
leucine-rich repeat 153..176 CDD:275380 8/22 (36%)
TPKR_C2 185..235 CDD:326558 8/24 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.