back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kek1 and Lrg1

DIOPT Version :9

Sequence 1:	NP_001303320.1	Gene:	kek1 / 34688	FlyBaseID:	FBgn0015399	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_084072.1	Gene:	Lrg1 / 76905	MGIID:	1924155	Length:	342	Species:	Mus musculus

Alignment Length:	251	Identity:	72/251 - (28%)
Similarity:	104/251 - (41%)	Gaps:	57/251 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 PNTQVLDMSGNKLQTLSNEQF-----IRA-----NLL------------NLQKLYLRNCKIGEIE 163
            |..:.|.:|.|:||.||.|..     :||     |.|            ||..|.||..::.|:.
Mouse    85 PGLRELHLSSNRLQALSPELLAPVPRLRALDLTRNALRSLPPGLFSTSANLSTLVLRENQLREVS 149

  Fly   164 RETFKGLTNLVELDLSHNLLVTVPS-----------LALGH-----IPS--------LRELTLAS 204
            .:..:||..|..|||:.|.|.::||           |.||:     :|.        |:.|.|..
Mouse   150 AQWLQGLDALGHLDLAENQLSSLPSGLLASLGALHTLDLGYNLLESLPEGLLRGPRRLQRLHLEG 214

  Fly   205 NHIHKIESQAFGNTPSLHKLDLSHCDIQTISAQAFGGLQGLTLLRLNGNKLSELLPKTIETLSR- 268
            |.:.::|.......|.|..|.|:...:..::..:|.|||.|.:|.|:.|.||...|.....|.|
Mouse   215 NRLQRLEDSLLAPQPFLRVLFLNDNQLVGVATGSFQGLQHLDMLDLSNNSLSSTPPGLWAFLGRP 279

  Fly   269 ----LHGIELHDNPWLCDCRLRDTKLWLM-KRNIPYPVAPVCSGGPE-----RIID 314
                ..|.::..|||:||..|.|...||: .||..:........|||     |::|
Mouse   280 TRDMQDGFDISHNPWICDKNLADLCRWLVANRNKMFSQNDTRCAGPEAMKGQRLLD 335

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.