Protein Alignment kek1 and Lrrc4c

DIOPT Version :10

• Sequence 1: NP_523559.3
• Gene: kek1 / 34688
• FlyBaseID: FBgn0015399
• Length: 880
• Species: Drosophila melanogaster
• Sequence 2: NP_001101223.1
• Gene: Lrrc4c / 311236
• RGDID: 1311013
• Length: 640
• Species: Rattus norvegicus
• Alignment Length: 504
• Identity: 129/504 - (25%)
• Similarity: 198/504 - (39%)
• Gaps: 111/504 - (22%)

  Fly    89 TCQTVCACKWKGGKQTVECIDRHLIQIPEHIDPNTQVLDMSGNKLQTLSNEQFIRANLLNLQKLY 153
            ||.:||:|..:..|  |.|:.::|.::|:.|..||::|::..|::|.:....|  .:|.:|:.|.
  Rat    46 TCPSVCSCSNQFSK--VICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSF--KHLRHLEILQ 106

  Fly   154 LRNCKIGEIERETFKGLTNLVELDLSHNLLVTVPSLALGHIPSLRELTLASNHIHKIESQAFGNT 218
            |....|..||...|.||.||..|:|..|.|.|:|:.|..::..|:||.|.:|.|..|.|.||...
  Rat   107 LSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRI 171

  Fly   219 PSLHKLDLSH-------------------------CD---------------------------- 230
            |||.:|||..                         |:
  Rat   172 PSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRP 236

  Fly   231 ------------------IQTISAQAFGGLQGLTLLRLNGNKLSELLPKTIET-LSRLHGIELHD 276
                              ||.|...||..||.|..:.|..|.|: |||..:.| |..|..|.||.
  Rat   237 GSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLT-LLPHDLFTPLHHLERIHLHH 300

  Fly   277 NPWLCDCRLRDTKLWLMKRNIPYPVAPVCS--GGPERIIDRSFADLHVDEFAC-RPEMLPISHYV 338
            |||.|:|.:.....|:  |::.......|:  ..|..:..|...:|..:.|.| .|.::.....:
  Rat   301 NPWNCNCDILWLSWWI--RDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADL 363

  Fly   339 EAAMGENASITCRARAVPAANINWYW-NGRLLANNSAFTAYQ-RIHMLEQVEGGFEKRSKLVLTN 401
            ....|..|.:.||| :....:::|.. ||.::.:.    ||: ||.:|..        ..|..||
  Rat   364 NVTEGMAAELKCRA-STSLTSVSWITPNGTVMTHG----AYKVRIAVLSD--------GTLNFTN 415

  Fly   402 AQETDSSEFYCVAENRAGMAEANFTLHVSMRAAGMASLGSGQIVGLSAALVALIVFALGVIMCLL 466
            ....|:..:.|:..|..|...|:.||:|:.......|.       .|...|..:..:........
  Rat   416 VTVQDTGMYTCMVSNSVGNTTASATLNVTAATTTPFSY-------FSTVTVETMEPSQDEARTTD 473

  Fly   467 LRVKRQPYVDSKTPNHMEVITSVNHQNSITNK---TQPATG-NGSIGGV 511
            ..|...|.:|.:|.|   |.||:..|::.:.:   |.|.|. |..|.|:
  Rat   474 NNVGPTPVIDWETTN---VTTSLTPQSTRSTEKTFTIPVTDINSGIPGI 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek1	NP_523559.3	leucine-rich repeat	103..122	CDD:275380	5/18 (28%)
		LRR	<122..>277	CDD:443914	62/226 (27%)
		leucine-rich repeat	123..148	CDD:275380	6/24 (25%)
		leucine-rich repeat	149..172	CDD:275380	9/22 (41%)
		leucine-rich repeat	173..196	CDD:275380	8/22 (36%)
		leucine-rich repeat	197..220	CDD:275380	10/22 (45%)
		leucine-rich repeat	221..244	CDD:275380	11/93 (12%)
		leucine-rich repeat	245..268	CDD:275380	9/23 (39%)
		LRRCT	277..327	CDD:214507	12/51 (24%)
		IG_like	338..429	CDD:214653	23/92 (25%)
		Ig strand B	346..350	CDD:409353	1/3 (33%)
		Ig strand C	359..363	CDD:409353	0/3 (0%)
		Ig strand E	395..399	CDD:409353	1/3 (33%)
		Ig strand F	409..414	CDD:409353	1/4 (25%)
		Ig strand G	422..425	CDD:409353	1/2 (50%)
Lrrc4c	NP_001101223.1	LRRNT	47..80	CDD:214470	12/34 (35%)
		LRR	<76..325	CDD:443914	69/253 (27%)
		leucine-rich repeat	78..101	CDD:275380	6/24 (25%)
		leucine-rich repeat	102..125	CDD:275380	9/22 (41%)
		leucine-rich repeat	126..149	CDD:275380	8/22 (36%)
		leucine-rich repeat	150..173	CDD:275380	10/22 (45%)
		leucine-rich repeat	174..198	CDD:275380	4/23 (17%)
		leucine-rich repeat	199..220	CDD:275380	1/20 (5%)
		leucine-rich repeat	221..244	CDD:275380	0/22 (0%)
		leucine-rich repeat	245..268	CDD:275380	6/22 (27%)
		leucine-rich repeat	269..290	CDD:275380	8/21 (38%)
		IG_like	360..443	CDD:214653	23/95 (24%)
		Ig strand B	371..375	CDD:409390	1/3 (33%)
		Ig strand C	383..387	CDD:409390	0/3 (0%)
		Ig strand E	409..413	CDD:409390	1/3 (33%)
		Ig strand F	423..428	CDD:409390	1/4 (25%)
		Ig strand G	436..439	CDD:409390	1/2 (50%)