DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek1 and Rtn4rl1

DIOPT Version :9

Sequence 1:NP_001303320.1 Gene:kek1 / 34688 FlyBaseID:FBgn0015399 Length:880 Species:Drosophila melanogaster
Sequence 2:NP_852042.1 Gene:Rtn4rl1 / 303311 RGDID:727812 Length:445 Species:Rattus norvegicus


Alignment Length:437 Identity:96/437 - (21%)
Similarity:159/437 - (36%) Gaps:78/437 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    90 CQTVCACKWKGGKQTVECIDRHLIQIPEHIDPNTQVLDMSGNKLQTLSNEQFIRANLLNLQKLYL 154
            |...|.|  .....||.|...:...|||.|..:::.:.:..|.:..|....|..|    :..|::
  Rat    25 CPRDCVC--YPSPMTVSCQAHNFAAIPEGIPEDSERIFLQNNHITFLQQGHFSPA----MVTLWI 83

  Fly   155 RNCKIGEIERETFKGLTNLVELDLSHNL-------------------------LVTVPSLALGHI 194
            .:..|..|...||:|..:|.||||..|.                         |.::|:...|.:
  Rat    84 YSNNITFIAPNTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSSLPAGIFGGL 148

  Fly   195 PSLRELTLASNHIHKIESQAF------------GN------------TPSLHKLDLSHCDIQTIS 235
            .||:.|.|..|||..::...|            ||            ..:|.:|.|....:|.:.
  Rat   149 HSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGQGIFRGLVNLDRLLLHENQLQWVH 213

  Fly   236 AQAFGGLQGLTLLRLNGNKLSELLPKTIETLSRLHGIELHDNPWLCDCRLRDTKLWLMKRNIPYP 300
            .:||..|..||.|.|..|.|:||....:..|..|..:.|:.|.|.|.||.|....||.:......
  Rat   214 HKAFHDLHRLTTLFLFNNSLTELQGDCLAPLVALEFLRLNGNAWDCGCRARSLWEWLRRFRGSSS 278

  Fly   301 VAPVCSGGPERIIDRSFADLHVDEFA-CRPEMLPISHYVEAAMGENASITCRARAVP---AANIN 361
            |.|..:  ||....:....|.|::|. |.....|  |.:::.....:....|....|   |:...
  Rat   279 VVPCAT--PELRQGQDLKSLRVEDFRNCTGPASP--HQIKSHTLSTSDRAARKEHHPSHGASRDK 339

  Fly   362 WYWNGRLLANNSA-------FTAYQRIHMLEQVEGGFEKRSKLVLTNAQETDSSEFYCVAENRAG 419
            .:.:|.|..:.|.       .|:::..:.:.:...|  |....:...|.:......:.:......
  Rat   340 GHPHGHLPGSRSGSKKPGKNCTSHRNRNQISKGSAG--KELPELQDYAPDYQHKFSFDIMPTARP 402

  Fly   420 MAEANFTLHVSMRA-AGMASLGSGQIVGLSAALVALIVFALGVIMCL 465
            ..:........:|| :|:....||..:|     |:|:.:.||:::.|
  Rat   403 KRKGKCARRTPIRAPSGVQQASSGTALG-----VSLLAWILGLVVSL 444

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek1NP_001303320.1 leucine-rich repeat 103..122 CDD:275380 7/18 (39%)
LRR_RI <119..277 CDD:238064 48/206 (23%)
leucine-rich repeat 123..148 CDD:275380 4/24 (17%)
LRR_8 148..207 CDD:290566 20/83 (24%)
leucine-rich repeat 149..172 CDD:275380 6/22 (27%)
leucine-rich repeat 173..196 CDD:275380 9/47 (19%)
LRR_8 195..255 CDD:290566 22/83 (27%)
leucine-rich repeat 197..220 CDD:275380 9/46 (20%)
leucine-rich repeat 221..244 CDD:275380 7/22 (32%)
leucine-rich repeat 245..268 CDD:275380 9/22 (41%)
LRRCT 277..327 CDD:214507 15/50 (30%)
IG_like 338..429 CDD:214653 10/100 (10%)
Ig 346..426 CDD:143165 10/89 (11%)
Rtn4rl1NP_852042.1 leucine-rich repeat 37..58 CDD:275380 7/20 (35%)
LRR 1 55..76 3/20 (15%)
LRR 2 77..98 6/24 (25%)
leucine-rich repeat 78..101 CDD:275380 6/22 (27%)
LRR_8 85..132 CDD:404697 11/46 (24%)
LRR 3 101..123 6/21 (29%)
leucine-rich repeat 102..126 CDD:275380 6/23 (26%)
PPP1R42 126..>255 CDD:411060 31/128 (24%)
LRR 4 126..147 2/20 (10%)
leucine-rich repeat 127..150 CDD:275380 3/22 (14%)
LRR 5 150..171 8/20 (40%)
leucine-rich repeat 151..174 CDD:275380 7/22 (32%)
LRR_8 174..233 CDD:404697 14/58 (24%)
LRR 6 174..195 2/20 (10%)
leucine-rich repeat 175..198 CDD:275380 2/22 (9%)
LRR 7 198..219 6/20 (30%)
leucine-rich repeat 199..222 CDD:275380 7/22 (32%)
LRR 8 222..243 8/20 (40%)
leucine-rich repeat 223..246 CDD:275380 9/22 (41%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 304..380 12/79 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 401..421 3/19 (16%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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