DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek1 and Slitrk4

DIOPT Version :9

Sequence 1:NP_001303320.1 Gene:kek1 / 34688 FlyBaseID:FBgn0015399 Length:880 Species:Drosophila melanogaster
Sequence 2:NP_001352040.1 Gene:Slitrk4 / 245446 MGIID:2442509 Length:837 Species:Mus musculus


Alignment Length:380 Identity:96/380 - (25%)
Similarity:153/380 - (40%) Gaps:78/380 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MHIREAVFLVLTLLPGMILGTRYNQLHLYANGGASSSGPGGYRPAPSSQNEVYSIADSQPMTEDG 65
            ::|.||:....:.|.|.:| ...|:..|...|..|..   ..|..|.||.            |:|
Mouse   235 IYIGEAICETPSDLYGRLL-KETNKQELCPMGTGSDF---DVRILPPSQQ------------ENG 283

  Fly    66 YMPPSQHF-----------PP--------------------------THSDLDPPAQQQSTCQTV 93
            :..|:.|.           ||                          ::....||.   :.|...
Mouse   284 FTTPNGHTTQTTLHRLVTKPPKTTNPSKISGIVAGKALSNRNLSQIVSYQTRVPPL---TPCPVP 345

  Fly    94 CACKWKGGK--QTVECIDRHLIQIPEHIDP---NTQVLDMSGNKLQTLSNEQFIRANLLNLQKLY 153
            |.||.....  .:|.|.::: ||....:.|   |.:.|.::||.::.:....|.....|:|  |:
Mouse   346 CFCKTHPSDLGLSVNCQEKN-IQSMSELTPKPLNAKKLHVNGNNIKDVDISDFTEFEGLDL--LH 407

  Fly   154 LRNCKIGEIERETFKGLTNLVELDLSHNLLVTV-PSLALGHIPSLRELTLASNHIHKIESQAFGN 217
            |.:.:|..|:.|.|..||||..|.|:.|.:..: |.:..| :.:|:.|.|..|.|.:|.:..|.:
Mouse   408 LGSNQITLIKGEVFHNLTNLRRLYLNGNQIERLYPEIFSG-LHNLQYLYLEYNLIKEILAGTFDS 471

  Fly   218 TPSLHKLDLSHCDIQTISAQAFGGLQGLTLLRLNGNKLSEL-LPKTIETLSRLHGIELHDNPWLC 281
            .|:|..|.|::..::::....|.|.. |..|.|..||...| :...::.|..|..|:|..|||.|
Mouse   472 MPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDC 535

  Fly   282 DCRLRDTKLWLMKRNIPYPVAPVCSGGPERIIDRSFADLHV----DEFACRPEML 332
            .|.|...||||.|.|....|..:....|.:     ||::.:    :|..| |::|
Mouse   536 TCDLVALKLWLEKLNDGIVVKELKCETPVQ-----FANIELKSLKNEILC-PKLL 584

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek1NP_001303320.1 leucine-rich repeat 103..122 CDD:275380 5/21 (24%)
LRR_RI <119..277 CDD:238064 46/162 (28%)
leucine-rich repeat 123..148 CDD:275380 4/24 (17%)
LRR_8 148..207 CDD:290566 20/59 (34%)
leucine-rich repeat 149..172 CDD:275380 8/22 (36%)
leucine-rich repeat 173..196 CDD:275380 6/23 (26%)
LRR_8 195..255 CDD:290566 17/59 (29%)
leucine-rich repeat 197..220 CDD:275380 7/22 (32%)
leucine-rich repeat 221..244 CDD:275380 5/22 (23%)
leucine-rich repeat 245..268 CDD:275380 7/23 (30%)
LRRCT 277..327 CDD:214507 17/53 (32%)
IG_like 338..429 CDD:214653
Ig 346..426 CDD:143165
Slitrk4NP_001352040.1 internalin_A <15..>253 CDD:380193 5/17 (29%)
LRR 1 60..81
leucine-rich repeat 63..84 CDD:275380
LRR_8 83..143 CDD:404697
LRR 2 84..105
leucine-rich repeat 85..108 CDD:275380
LRR 3 108..129
leucine-rich repeat 109..132 CDD:275380
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275380
LRR 5 156..177
leucine-rich repeat 157..182 CDD:275380
LRR 6 179..200
leucine-rich repeat 183..325 CDD:275380 20/105 (19%)
leucine-rich repeat 326..402 CDD:275380 16/79 (20%)
leucine-rich repeat 358..378 CDD:275380 5/20 (25%)
PPP1R42 359..>550 CDD:411060 61/195 (31%)
LRR 7 378..399 5/20 (25%)
LRR_8 402..461 CDD:404697 21/61 (34%)
LRR 8 402..423 8/22 (36%)
leucine-rich repeat 403..426 CDD:275380 9/24 (38%)
LRR 9 426..447 6/20 (30%)
leucine-rich repeat 427..450 CDD:275380 6/23 (26%)
LRR 10 450..471 7/20 (35%)
leucine-rich repeat 451..472 CDD:275380 7/20 (35%)
LRR 11 474..495 4/20 (20%)
leucine-rich repeat 475..496 CDD:275380 4/20 (20%)
LRR 12 497..518 6/21 (29%)
leucine-rich repeat 498..522 CDD:275380 7/23 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 113 1.000 Inparanoid score I4837
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

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