DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kek1 and Lrrc38

DIOPT Version :9

Sequence 1:NP_001303320.1 Gene:kek1 / 34688 FlyBaseID:FBgn0015399 Length:880 Species:Drosophila melanogaster
Sequence 2:XP_006538918.1 Gene:Lrrc38 / 242735 MGIID:2442845 Length:410 Species:Mus musculus


Alignment Length:214 Identity:62/214 - (28%)
Similarity:93/214 - (43%) Gaps:31/214 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    90 CQTVCACKWKGGKQTVECIDRHLIQIPEHIDPNTQVLDMSGNKLQTLSNEQFI-RANLLNLQKLY 153
            |...|||.   ...||:|.||.|..:|:....:.:.|.::||::|.:..:.|| ..:|:.|.   
Mouse   172 CPAGCACT---DPHTVDCRDRGLPSVPDPFPLDVRKLLVAGNRIQQIPEDFFIFHGDLVYLD--- 230

  Fly   154 LRNCKIGEIERETFKGLTNLVELDLSHNLLVTVPSLALGHIPSLRELTLASNHIHKIESQAFGNT 218
            .||..:..:|..||.|...|..||||:|.|..:.:.|......|.:|:||:||:..:...||.: 
Mouse   231 FRNNSLRSLEEGTFSGSGKLAFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNHLAGVHEAAFES- 294

  Fly   219 PSLHKLDLSHCDIQTISAQAFGGLQGLTLLRLNGNKLSELLPKTIETLSRLHGIELHDNPWLCDC 283
                                   |:.|.:|.||.|.|..|....::.|..|..:.|..|||||||
Mouse   295 -----------------------LESLQVLELNDNNLRSLNVAALDALPALRTVRLDGNPWLCDC 336

  Fly   284 RLRDTKLWLMKRNIPYPVA 302
            .......|:.:.....|.|
Mouse   337 DFAHLFSWIQENTSKLPKA 355

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek1NP_001303320.1 leucine-rich repeat 103..122 CDD:275380 7/18 (39%)
LRR_RI <119..277 CDD:238064 41/158 (26%)
leucine-rich repeat 123..148 CDD:275380 7/25 (28%)
LRR_8 148..207 CDD:290566 20/58 (34%)
leucine-rich repeat 149..172 CDD:275380 7/22 (32%)
leucine-rich repeat 173..196 CDD:275380 8/22 (36%)
LRR_8 195..255 CDD:290566 14/59 (24%)
leucine-rich repeat 197..220 CDD:275380 8/22 (36%)
leucine-rich repeat 221..244 CDD:275380 1/22 (5%)
leucine-rich repeat 245..268 CDD:275380 8/22 (36%)
LRRCT 277..327 CDD:214507 10/26 (38%)
IG_like 338..429 CDD:214653
Ig 346..426 CDD:143165
Lrrc38XP_006538918.1 LRRNT 171..202 CDD:214470 11/32 (34%)
leucine-rich repeat 182..204 CDD:275380 7/21 (33%)
LRR_8 202..260 CDD:338972 20/60 (33%)
leucine-rich repeat 205..225 CDD:275380 6/19 (32%)
leucine-rich repeat 226..249 CDD:275380 8/25 (32%)
leucine-rich repeat 250..273 CDD:275380 8/22 (36%)
LRR_8 273..331 CDD:338972 19/81 (23%)
leucine-rich repeat 274..297 CDD:275380 9/46 (20%)
leucine-rich repeat 298..321 CDD:275380 8/22 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.