DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kek1 and Lrrc55

DIOPT Version :9

Sequence 1:NP_001303320.1 Gene:kek1 / 34688 FlyBaseID:FBgn0015399 Length:880 Species:Drosophila melanogaster
Sequence 2:XP_006499531.1 Gene:Lrrc55 / 241528 MGIID:2685197 Length:311 Species:Mus musculus


Alignment Length:268 Identity:68/268 - (25%)
Similarity:103/268 - (38%) Gaps:78/268 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 HSDLDPPAQQQSTCQTVCACKWKGGKQTVECIDRHLIQIPEHIDPNTQVLDMSGNKLQTLSNEQF 141
            |||..      ::|..:|.|:    .|.|:|.::.|..:|..:..:|:.|.::.|::..:.....
Mouse    44 HSDAG------TSCPVLCTCR----NQVVDCSNQRLFSVPPDLPMDTRNLSLAHNRIAAVPPGYL 98

  Fly   142 IRANLLNLQKLYLRNCKIGEIERETFKGLTNLVELDLSHNLLVTVPS-----------LALGHIP 195
              ...:.|:.|.|||..:.|:....|.....|..||||:|.|..||:           :.|.|.|
Mouse    99 --TCYMELRVLDLRNNSLMELPPGLFLHAKRLAHLDLSYNNLSHVPADMFREAHGLVHIDLSHNP 161

  Fly   196 SLRELTLASNHIHKIESQAFGNTPSLHKLDLSHCDIQTISAQAFGGLQGLTLLRLNGNKLSELLP 260
            .||          ::..|||.....|..||||:..:..:|.:|..||.||..|::.|        
Mouse   162 WLR----------RVHPQAFQGLVHLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGG-------- 208

  Fly   261 KTIETLSRLHGIELHDNPWLCDCRLRDTKLWLMKRNIPYPVAPVCSGGPERIIDRSFADLHVDEF 325
                            |||:|.|.:.....||..|                 |.|..||..:.| 
Mouse   209 ----------------NPWVCGCTMEPLLKWLRNR-----------------IQRCTADSQLAE- 239

  Fly   326 ACR--PEM 331
             ||  ||:
Mouse   240 -CRGPPEV 246

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek1NP_001303320.1 leucine-rich repeat 103..122 CDD:275380 5/18 (28%)
LRR_RI <119..277 CDD:238064 40/168 (24%)
leucine-rich repeat 123..148 CDD:275380 3/24 (13%)
LRR_8 148..207 CDD:290566 21/69 (30%)
leucine-rich repeat 149..172 CDD:275380 7/22 (32%)
leucine-rich repeat 173..196 CDD:275380 11/33 (33%)
LRR_8 195..255 CDD:290566 19/59 (32%)
leucine-rich repeat 197..220 CDD:275380 5/22 (23%)
leucine-rich repeat 221..244 CDD:275380 9/22 (41%)
leucine-rich repeat 245..268 CDD:275380 3/22 (14%)
LRRCT 277..327 CDD:214507 13/49 (27%)
IG_like 338..429 CDD:214653
Ig 346..426 CDD:143165
Lrrc55XP_006499531.1 LRRNT 51..82 CDD:214470 9/34 (26%)
leucine-rich repeat 60..79 CDD:275380 5/18 (28%)
leucine-rich repeat 80..103 CDD:275380 3/24 (13%)
LRR_8 103..161 CDD:338972 18/57 (32%)
leucine-rich repeat 104..127 CDD:275380 7/22 (32%)
leucine-rich repeat 128..151 CDD:275380 9/22 (41%)
LRR_8 151..210 CDD:338972 21/92 (23%)
leucine-rich repeat 152..176 CDD:275380 8/33 (24%)
leucine-rich repeat 177..200 CDD:275380 9/22 (41%)
TPKR_C2 209..260 CDD:387596 17/57 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.