DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kek1 and Slitrk6

DIOPT Version :9

Sequence 1:NP_001303320.1 Gene:kek1 / 34688 FlyBaseID:FBgn0015399 Length:880 Species:Drosophila melanogaster
Sequence 2:NP_780708.1 Gene:Slitrk6 / 239250 MGIID:2443198 Length:840 Species:Mus musculus


Alignment Length:236 Identity:67/236 - (28%)
Similarity:107/236 - (45%) Gaps:20/236 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 PPAQQQSTCQTVCACKWKGGKQTVECIDRHLIQIPEHIDPNTQVLDMS--GNKLQTLSNEQFIRA 144
            |....:.:|.|:|.|:.|.|...:.|.::.:.::.:...|.::...:|  .|.|..|....|  :
Mouse    23 PMPSVRGSCDTLCNCEEKDGIMIINCEEKGINKLSQISVPPSRPFHLSLLNNGLTMLHTNDF--S 85

  Fly   145 NLLNLQKLYLRNCKIGEIERETFKGLTNLVELDLSHNLLVTVPSLALGHIPSLRELTLASNHIHK 209
            .|.|...::|....|.:||...|.||..|.:|.::||.|..:.......:.:|..|...:|.|..
Mouse    86 GLTNALSIHLGFNNIADIETGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITI 150

  Fly   210 IESQAFGNTPSLHKLDLSHCDIQTISAQAFGGLQGLTLLRLNGNKLSELLPKT--IETLSRLHGI 272
            ||..||.....|..|.|:...|:::....|..:. ||.|.|.||:| :.||..  :|.:.|:..:
Mouse   151 IEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVP-LTHLDLRGNQL-QTLPYVGFLEHIGRILDL 213

  Fly   273 ELHDNPWLCDCRLRDTKLWLMKRNIPYPVAPVCSGGPERII 313
            :|.||.|.|:|.|...|.||  .|:|          |:.||
Mouse   214 QLEDNKWACNCELLQLKNWL--ENMP----------PQSII 242

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek1NP_001303320.1 leucine-rich repeat 103..122 CDD:275380 1/18 (6%)
LRR_RI <119..277 CDD:238064 45/161 (28%)
leucine-rich repeat 123..148 CDD:275380 6/26 (23%)
LRR_8 148..207 CDD:290566 16/58 (28%)
leucine-rich repeat 149..172 CDD:275380 7/22 (32%)
leucine-rich repeat 173..196 CDD:275380 5/22 (23%)
LRR_8 195..255 CDD:290566 19/59 (32%)
leucine-rich repeat 197..220 CDD:275380 8/22 (36%)
leucine-rich repeat 221..244 CDD:275380 5/22 (23%)
leucine-rich repeat 245..268 CDD:275380 10/24 (42%)
LRRCT 277..327 CDD:214507 13/37 (35%)
IG_like 338..429 CDD:214653
Ig 346..426 CDD:143165
Slitrk6NP_780708.1 leucine-rich repeat 68..89 CDD:275380 6/22 (27%)
LRR_8 69..124 CDD:290566 18/56 (32%)
LRR 1 89..110 6/20 (30%)
leucine-rich repeat 94..113 CDD:275380 7/18 (39%)
LRR 2 113..134 5/20 (25%)
LRR_8 114..172 CDD:290566 16/57 (28%)
leucine-rich repeat 114..137 CDD:275380 5/22 (23%)
LRR 3 137..158 8/20 (40%)
leucine-rich repeat 138..161 CDD:275380 8/22 (36%)
LRR_8 161..219 CDD:290566 18/59 (31%)
LRR 4 161..182 5/20 (25%)
leucine-rich repeat 162..177 CDD:275380 4/14 (29%)
LRR 5 184..205 9/22 (41%)
leucine-rich repeat 185..260 CDD:275380 26/71 (37%)
leucine-rich repeat 210..222 CDD:275378 4/11 (36%)
TPKR_C2 218..268 CDD:301599 13/37 (35%)
leucine-rich repeat 261..411 CDD:275380
LRR 6 363..384
leucine-rich repeat 365..387 CDD:275380
LRR_8 387..444 CDD:290566
LRR 7 387..408
LRR_4 388..426 CDD:289563
LRR_4 410..449 CDD:289563
LRR 8 411..432
leucine-rich repeat 412..435 CDD:275380
LRR_8 435..493 CDD:290566
LRR 9 435..456
leucine-rich repeat 436..459 CDD:275380
LRR 10 459..480
leucine-rich repeat 460..481 CDD:275380
LRR 11 482..503
LRRCT 516..566 CDD:214507
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 717..736
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 113 1.000 Inparanoid score I4837
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

Return to query results.
Submit another query.