DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek1 and lron-2

DIOPT Version :9

Sequence 1:NP_001303320.1 Gene:kek1 / 34688 FlyBaseID:FBgn0015399 Length:880 Species:Drosophila melanogaster
Sequence 2:NP_505402.1 Gene:lron-2 / 179309 WormBaseID:WBGene00022789 Length:575 Species:Caenorhabditis elegans


Alignment Length:316 Identity:77/316 - (24%)
Similarity:118/316 - (37%) Gaps:61/316 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MHIREAVFLVLTLLPGMILGTRYNQLHLYANGGASSSGPGGYRP-------APSSQNEVYSIADS 58
            |.:|..:...|.:       |.|.|..  |..||....|..|.|       |.|.||.:.:|..:
 Worm     1 MGLRAIILATLVV-------TVYGQCP--ALSGACRCAPSVYEPVAIICQNAGSLQNAIQAIQAA 56

  Fly    59 QPMTEDGYMPPSQHFPPTHSDLDPPAQQQSTCQTVCACKWKGGKQTVECIDRHLIQIPEHIDPNT 123
            :.:..|..         |..|...|....:..|:....:....:.|::.||......| .:|...
 Worm    57 RDIPIDSL---------TILDTAIPTIPANAFQSFTILRLVLNRNTLQNIDDQAFNGP-LLDSLI 111

  Fly   124 QVLDMSGNKLQTLSNEQFIRANLLNLQKLYLRNCKIGEI-------------------------- 162
            : ||::.|.|..:......|  |.||:||||...:|.::                          
 Worm   112 E-LDLNDNNLGQIPQTGIPR--LRNLRKLYLNRNRINQLSSTAFNAFESRDLLLKLELAGNRLTD 173

  Fly   163 ----ERETFKGLTNLVELDLSHNLLVTVPSLAL-GHIPSLRELTLASNHIHKIESQAFGNTPSLH 222
                :...|:.||.|.||.|..|.|.::||.|| ....:|..|.|..|.|:::...|. :.|.|.
 Worm   174 ATLGDATVFRPLTLLQELSLETNSLTSIPSSALVNQRNTLTNLNLGLNSINEVPVGAL-DFPVLS 237

  Fly   223 KLDLSHCDIQTISAQAFGGLQGLTLLRLNGNKLSELLPKTIETLSRLHGIELHDNP 278
            .|.|....|..|..|||.|:..|..|.:.|||.....|:....:::|..:.:.:.|
 Worm   238 SLSLEFNGITVIPPQAFQGVPNLQFLYMTGNKFPSWAPEMFRYITQLKTLGIGETP 293

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek1NP_001303320.1 leucine-rich repeat 103..122 CDD:275380 5/18 (28%)
LRR_RI <119..277 CDD:238064 50/188 (27%)
leucine-rich repeat 123..148 CDD:275380 6/24 (25%)
LRR_8 148..207 CDD:290566 24/89 (27%)
leucine-rich repeat 149..172 CDD:275380 8/52 (15%)
leucine-rich repeat 173..196 CDD:275380 10/23 (43%)
LRR_8 195..255 CDD:290566 20/59 (34%)
leucine-rich repeat 197..220 CDD:275380 6/22 (27%)
leucine-rich repeat 221..244 CDD:275380 9/22 (41%)
leucine-rich repeat 245..268 CDD:275380 6/22 (27%)
LRRCT 277..327 CDD:214507 1/2 (50%)
IG_like 338..429 CDD:214653
Ig 346..426 CDD:143165
lron-2NP_505402.1 leucine-rich repeat 64..84 CDD:275380 4/28 (14%)
leucine-rich repeat 85..109 CDD:275380 4/24 (17%)
LRR_8 86..144 CDD:290566 17/61 (28%)
LRR_RI 109..294 CDD:238064 50/189 (26%)
leucine-rich repeat 110..133 CDD:275380 6/25 (24%)
LRR_8 132..198 CDD:290566 15/65 (23%)
leucine-rich repeat 134..157 CDD:275380 6/22 (27%)
leucine-rich repeat 161..187 CDD:275380 2/25 (8%)
leucine-rich repeat 188..211 CDD:275380 10/22 (45%)
LRR_8 212..270 CDD:290566 20/58 (34%)
leucine-rich repeat 213..235 CDD:275380 6/22 (27%)
leucine-rich repeat 236..259 CDD:275380 9/22 (41%)
leucine-rich repeat 260..283 CDD:275380 6/22 (27%)
LRR_8 282..342 CDD:290566 2/12 (17%)
leucine-rich repeat 284..307 CDD:275380 2/10 (20%)
leucine-rich repeat 308..355 CDD:275380
LRR_8 330..390 CDD:290566
leucine-rich repeat 356..377 CDD:275380
leucine-rich repeat 380..400 CDD:275380
Ca_hom_mod <481..>504 CDD:291464
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24366
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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