DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek1 and amigo2

DIOPT Version :9

Sequence 1:NP_001303320.1 Gene:kek1 / 34688 FlyBaseID:FBgn0015399 Length:880 Species:Drosophila melanogaster
Sequence 2:XP_004913023.1 Gene:amigo2 / 100489302 XenbaseID:XB-GENE-6467798 Length:518 Species:Xenopus tropicalis


Alignment Length:470 Identity:110/470 - (23%)
Similarity:186/470 - (39%) Gaps:103/470 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 TCQTVCACKWKGGKQTVECIDRHLIQIPEHIDPNTQVLDMSGNKLQTLSNEQFIRANLLNLQKLY 153
            ||..||.|    ....|.|.:::|..:|.......:.||:|.||:..|..:.| ...|..|..|.
 Frog    39 TCPPVCIC----ASDIVSCTNKNLSVVPRTHFKFIRKLDLSYNKIGFLDPDWF-PFLLEKLDTLI 98

  Fly   154 LRNCKIGEIERETFKGLTNLVELDLSHNLLVTVPSLALGHIPSLRELTLASNHIHKIESQAFGNT 218
            |.:..:..|...:|..:.|:..||||.|.|.|:.:.....:..|..|.|.:|.:..|:|.|||..
 Frog    99 LNHNTVSSISTGSFSTIPNVRYLDLSSNNLRTLSNPVFQELKMLEVLLLYNNQLTHIDSGAFGGL 163

  Fly   219 PSLHKLDLSHCDIQTISAQAFGG---LQGLTLLRLNGNKLSELLPKTIETLS-----RLHGIELH 275
            ..|.||.||...:.......|.|   |..|.||.::.||: :::|  ::.:|     :|.||.:|
 Frog   164 HKLQKLYLSGNVLTQFPVDLFVGRSKLTELVLLDMSYNKI-QVVP--VQQISLIPARQLSGIYIH 225

  Fly   276 DNPWLCDCRLRD-----------------------------TKLWLMKRNIPYPVAPVCSGGPER 311
            :|.::|||.|..                             |||.|::.:...     ||   |.
 Frog   226 ENTFVCDCALNSMLNFWYHRHFSPVVDFKNDYSCILSSDLKTKLLLIQESFLN-----CS---EN 282

  Fly   312 IIDRSFADLHVDEFACRPEMLPISHYVEAAMGENASITCRARAVPAANINWYW---NGRLLANNS 373
            .::.||   |...|           ..||.:||...:.|.::.:.|.. .:.|   :.|.|..: 
 Frog   283 TVNESF---HAYGF-----------LYEAQVGERLVVHCDSKIIDAGT-QFIWVSPDNRTLEPD- 331

  Fly   374 AFTAYQRIHMLEQVEGGFEKRSKLVLTNAQETDSSEFYCVAENRAGMAEANFTLHVSMRAAGMAS 438
                .:..|......|..|      :.:||..||..:.|:|.|:..:  .|.|:.:.:..:...:
 Frog   332 ----IKTDHFHVFYNGSLE------IEDAQIGDSGVYSCIAINKKSL--LNETIDIRITVSNFTT 384

  Fly   439 LGSGQIVGLSAALVALIVFALGVIMCLLL-------------RVKRQPYVDSKTPNHMEVI-TSV 489
            ..|......:.|...|....:.:::.||.             :.||:|   :::..|..:: |:.
 Frog   385 NKSQSHEAFNTAFTTLAACVVSIVLVLLYLYLTPCRCWCKSKKKKRKP---NQSSAHSSILSTTP 446

  Fly   490 NHQNSITNKTQPATG 504
            :|..  ||:.:.:||
 Frog   447 SHDP--TNERKSSTG 459

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek1NP_001303320.1 leucine-rich repeat 103..122 CDD:275380 4/18 (22%)
LRR_RI <119..277 CDD:238064 49/165 (30%)
leucine-rich repeat 123..148 CDD:275380 8/24 (33%)
LRR_8 148..207 CDD:290566 17/58 (29%)
leucine-rich repeat 149..172 CDD:275380 5/22 (23%)
leucine-rich repeat 173..196 CDD:275380 7/22 (32%)
LRR_8 195..255 CDD:290566 21/62 (34%)
leucine-rich repeat 197..220 CDD:275380 9/22 (41%)
leucine-rich repeat 221..244 CDD:275380 8/25 (32%)
leucine-rich repeat 245..268 CDD:275380 7/27 (26%)
LRRCT 277..327 CDD:214507 16/78 (21%)
IG_like 338..429 CDD:214653 21/93 (23%)
Ig 346..426 CDD:143165 16/82 (20%)
amigo2XP_004913023.1 inl_like_NEAT_1 <55..>345 CDD:411101 78/321 (24%)
LRR_8 70..128 CDD:404697 19/58 (33%)
leucine-rich repeat 70..93 CDD:275380 8/23 (35%)
leucine-rich repeat 94..117 CDD:275380 5/22 (23%)
LRR_8 116..176 CDD:404697 22/59 (37%)
leucine-rich repeat 118..141 CDD:275380 7/22 (32%)
leucine-rich repeat 142..165 CDD:275380 9/22 (41%)
leucine-rich repeat 166..189 CDD:275380 7/22 (32%)
leucine-rich repeat 190..218 CDD:275380 8/30 (27%)
Ig <320..377 CDD:416386 15/69 (22%)
Ig strand C' 325..327 CDD:409353 0/1 (0%)
Ig strand D 333..340 CDD:409353 1/6 (17%)
Ig strand E 343..347 CDD:409353 2/9 (22%)
Ig strand F 357..364 CDD:409353 2/6 (33%)
Ig strand G 367..377 CDD:409353 2/11 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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