DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MRP and NAP5

DIOPT Version :9

Sequence 1:	NP_723772.2	Gene:	MRP / 34686	FlyBaseID:	FBgn0032456	Length:	1549	Species:	Drosophila melanogaster
Sequence 2:	NP_177289.1	Gene:	NAP5 / 843474	AraportID:	AT1G71330	Length:	324	Species:	Arabidopsis thaliana

Alignment Length:	349	Identity:	122/349 - (34%)
Similarity:	182/349 - (52%)	Gaps:	55/349 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   736 DRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSA 800
            ||:||:|||:||:|..|::|||.||.|.|||:||||||||||||.:|||:|.|||:||.|||.||
plant     2 DRERYDKVIEACSLSKDLEILSFGDQTVIGERGINLSGGQKQRIHIARALYQDADIYLFDDPFSA 66

  Fly   801 VDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAF 865
            ||||.|.|:|:|.:  :|:|..||.:.|||.|.|||..|...|:|.|.||::|.::.::
plant    67 VDAHTGSHLFKEAL--RGLLCSKSVIYVTHQVEFLPSADLTLVMKDGRISQAGKYNDIL------ 123

  Fly   866 ADFIIQHLQEGNEEEEELNQIKRQISSTADVPELLGTVEKAIKLARTESLSDSISVTSADSLMGG 930
                                    ||.| |..||:|..::::.:..:   :|:.||:...:|...
plant   124 ------------------------ISGT-DFRELIGAHQESLAVVGS---ADASSVSENSALDEE 160

  Fly   931 GGSLRRR---TKRQDSHDSVASAASLKKKQ----EVEGKLIETEKSQTGGVEFAVYKHYIK-SVG 987
            .|.:|..   ..:|:|.|       ||..:    |.:.:.::.|:...|.|...||..||. :.|
plant   161 NGVVRDDIGFDGKQESQD-------LKNDKLDSGEPQRQFVQEEERAKGSVALDVYWKYITLAYG 218

  Fly   988 IFLSVATLVLNFVFQAFQIGSNLWLTQWAN--DQNVANDTGLRDMYLGVYGAFGFGQGVLAYFAV 1050
            ..|....|:...:||..|||||.|:. ||.  .::|.....|..:.: ||.|..||..:......
plant   219 GALVPFILLGQILFQLLQIGSNYWMA-WATPISEDVQAPVKLSTLMV-VYVALAFGSSLCILVRA 281

  Fly  1051 VIVYLGGFQAAKTIHNELLAVIIR 1074
            .::...|::.|..:.:::...|.|
plant   282 TLLVTAGYKTATELFHKMHHCIFR 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MRP	NP_723772.2	MRP_assoc_pro	14..1548	CDD:188098	122/349 (35%)
		ABC_membrane	338..601	CDD:279056
		ABCC_MRP_domain1	649..848	CDD:213217	68/111 (61%)
		ABC_membrane	988..1260	CDD:279056	23/89 (26%)
		ABCC_MRP_domain2	1308..1528	CDD:213211
NAP5	NP_177289.1	P-loop_NTPase	<1..112	CDD:304359	68/111 (61%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0054
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138195at2759
OrthoFinder	1	1.000	-	-		FOG0000087
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820