Protein Alignment MRP and abcb9

DIOPT Version :9

• Sequence 1: NP_723772.2
• Gene: MRP / 34686
• FlyBaseID: FBgn0032456
• Length: 1549
• Species: Drosophila melanogaster
• Sequence 2: NP_001119906.1
• Gene: abcb9 / 570148
• ZFINID: ZDB-GENE-050517-12
• Length: 789
• Species: Danio rerio
• Alignment Length: 649
• Identity: 171/649 - (26%)
• Similarity: 294/649 - (45%)
• Gaps: 116/649 - (17%)

  Fly   940 RQDSHDSVASAASLKKKQEVEGKLIETEKSQTGGVEFAVYKH----------YIKSVGIFLSVA- 993
            |:||.|:         ::.|:....|:|||...|.|   :.|          |.|.....||:|
Zfish   147 REDSEDT---------ERLVDETEDESEKSMKSGKE---HTHSGATIGRLLSYCKKDSSLLSIAF 199

  Fly   994 -TLVLNFVFQAFQIGSNLWLTQWANDQNV---ANDTGLRDMY-LGVYG-----AFGFGQGVLAY- 1047
             .|:|:.|.:||    ..:.|..|.|..|   :.|...:.|. |.|..     |.||..||.:.
Zfish   200 FFLLLSAVCEAF----IPYYTGQAIDGIVIQKSMDHFAKPMITLSVLALVSSIAIGFRGGVFSVT 260

  Fly  1048 FAVVIVYLGGFQAAKTIHNELLAVIIRGSVCRFFDITPIGRLLNSFSGD----MDVVDEELPATM 1108
            ||.:.:.|........:|.|:          .|||....|.:.:..:.|    .|::.:.:...:
Zfish   261 FARLNIRLRNLLFRSLMHQEI----------GFFDANHTGDITSRLTSDTTQVSDLISQNVNLFL 315

  Fly  1109 DSFM----TFIFMV-----LATIVVISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLESVS 1164
            .||:    .||||.     |:.:.::...   ::||:..:...||......|.|:  |.:...|:
Zfish   316 RSFVKAVGIFIFMFGMSWKLSVVTIMGFP---YIAVVSKLYGEYYKKLTKEVQTA--LAQANKVA 375

  Fly  1165 RSPIYSHFSETVTGASTIRAY----NVGDRFIEESDAK--VDKNQVCKYPSVIANRWLAIRLEMV 1223
                    .||::...|:|::    ..||.:.......  ::|.|...|...:   |.:...|:.
Zfish   376 --------EETISAMRTVRSFANEDQEGDMYYSRLQEMFVLNKKQAIAYACFM---WSSYISELA 429

  Fly  1224 GNLIILFASLFAVLGGQTNPGLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETK- 1287
            ..:.|||.....|:..|.:.|.:...|.|.|::.:.|..:..:.:.:...:.:.|::.||.:.|
Zfish   430 LQVAILFYGGHLVVTNQMSGGTLISFVIYELELGEALESISSVYTGLMQGVGAAEKVFEYIDRKP 494

  Fly  1288 ------QEAPWELEQDKNKPKNWPQEGRVEFQNFQVRY--REGLDLVLRGVSFNIQGGEKVGIVG 1344
                  ||||..|            ||:|||.|....|  |..:| ||:.|||:::.|:...:||
Zfish   495 KHALNGQEAPETL------------EGQVEFNNVTFAYPSRPEMD-VLKNVSFSLRPGQVTALVG 546

  Fly  1345 RTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLD--- 1406
            .:|.||||....|........|::.:||..:.:.......|::.::.|:||||:.::::|:.
Zfish   547 PSGGGKSSCVCLLENFYAPQQGQVLVDGRPVNTYQHKYYHSKVALVAQEPVLFARTVQMNISYGV 611

  Fly  1407 ---PFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVL 1468
               |.|     .:.:|...::...|:..|:.|.:..:.|.|..||.||:|.|.:||||:|..::|
Zfish   612 PEAPME-----AVIRAAINANAHDFITGLSKGYDSGVGEKGTQLSGGQKQRVAIARALIRSPRIL 671

  Fly  1469 VLDEATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELL 1532
            :|||||:|:|.|::.::|:.:....:|.|||.|||||:|:..:|.::|:|||.::|.....||:
Zfish   672 ILDEATSALDSESEYIVQQALNNLMREHTVLVIAHRLSTVERADNILVIDKGSVVEQGPHAELM 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MRP	NP_723772.2	MRP_assoc_pro	14..1548	CDD:188098	171/649 (26%)
		ABC_membrane	338..601	CDD:279056
		ABCC_MRP_domain1	649..848	CDD:213217
		ABC_membrane	988..1260	CDD:279056	67/302 (22%)
		ABCC_MRP_domain2	1308..1528	CDD:213211	77/227 (34%)
abcb9	NP_001119906.1	3a01208	46..745	CDD:273363	171/649 (26%)
		ABC_membrane	199..458	CDD:279056	62/288 (22%)
		P-loop_NTPase	500..725	CDD:304359	82/242 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000