Protein Alignment MRP and abcc13

DIOPT Version :10

• Sequence 1: NP_723772.2
• Gene: MRP / 34686
• FlyBaseID: FBgn0032456
• Length: 1549
• Species: Drosophila melanogaster
• Sequence 2: XP_073796816.1
• Gene: abcc13 / 559093
• ZFINID: ZDB-GENE-050517-26
• Length: 1025
• Species: Danio rerio
• Alignment Length: 1335
• Identity: 321/1335 - (24%)
• Similarity: 522/1335 - (39%)
• Gaps: 389/1335 - (29%)

  Fly   242 KMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHHWNQNVRKNYKNKARVEPKAQFSNGNVTFEN 306
            :|.:.|:|.||:..||..|..:||...:..:|.|.|.:. :.|||.::.:|
Zfish    28 RMVVMGHRGPLQLFDLLKLYNEDSVHTLCSVFDHEWEKQ-QNNYKERSDLE-------------- 77

  Fly   307 PHGEKNGRKKGMA--------SIMPPIYKSFGGVFLFGALMKLFTDTLTFAQPQVLSLIISFVEA 363
               :.:|||..:.        |::..::|:|....:...|::|.:|..:...|..:..:|.|.|.
Zfish    78 ---DDSGRKSLLVTSKTNAGYSLLYTLWKTFHPSLIKIVLLRLSSDLFSILVPITIRWVILFSER 139

  Fly   364 QDAEPEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTALINAIYR--KALRISNSTKKE 426
            | |...|.|..||:::|.......|....:..|..|:.......|...:||  |.|.:|:|::..
Zfish   140 Q-AMFGWTGYTYALVVFGALCCGAFSQHHFEKRSRIITANAHAILSGTVYRKIKTLSLSHSSRWH 203

  Fly   427 STVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGPSVLAGLAVMIILIPVNGV 491
            |......:::. :|:|..||...|..|||:||::.|.|..||.:||||||.|:.::::||||...
Zfish   204 SDTSHREDMLG-EAERVAELVVTLACIWSSPLRVTLYLGLLWAKLGPSVLVGVTLLLVLIPVKSA 267

  Fly   492 IASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRDKEIATLRSTAYLNA 556
            :..:.|..:......:::..:|:.|:|...:.|||..||..|.::|.:.|.:|:..||...:|.|
Zfish   268 VERKAKQLRRTHRVIREKSEQLIKEMLHKYQALKLLTWESWFFQRVTESRTRELEMLRIQGFLTA 332

  Fly   557 GTSFLWSCAPFLVSLVTFATYVLTSEANQLSVEKVLVSIALFDLMKLP-LTILPMLSVDIAETQV 620
            .:.....|.||||...:...:||..:.|.|:..::..|:..|.|::.| |..|.:.|| :.:.|.
Zfish   333 FSMLDSICMPFLVIFSSLGAFVLVDDGNVLTSSQIFTSVCFFRLLRPPLLEFLGLFSV-LKQAQQ 396

  Fly   621 SVNRINKFLNSEELDPNSVLHDSSKPHPMSIENGEFSWGDEITLRNINIEVKKGSLVALVGTVGS 685
            |...:.|...:|:|..:..|                               .||:      |..|
Zfish   397 SFCYLEKIFLTEDLGTSQFL-------------------------------TKGA------TEES 424

  Fly   686 GKSSVVQAFLGEMEKLAGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKR-----YNKVID 745
            ...|..|......||                    ||.:           |.||     .|:..:
Zfish   425 SADSTQQPCDECQEK--------------------QNDS-----------DEKRDHYHFRNEFRE 458

  Fly   746 ACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIF 810
            ||.                                          |||
Zfish   459 ACW------------------------------------------LYL----------------- 464

  Fly   811 EEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAFADFIIQHLQE 875
                                                                |||.    .|.
Zfish   465 ----------------------------------------------------GAFG----WHW-- 471

  Fly   876 GNEEEEELNQIKRQISSTADVPELLGTVEKAIKLARTESLSDSISVTSADSLMGGGGSLRRRTKR 940
                                                       :||.|.
Zfish   472 -------------------------------------------VSVCSL---------------- 477

  Fly   941 QDSHDSVASAASLKKKQEVEGKLIETEKSQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVFQAFQ 1005
                                                           ::|||.         |..
Zfish   478 -----------------------------------------------VYLSVC---------AVS 486

  Fly  1006 IGSNLWLTQWAND----QNVANDTGLRDMYLGVYGAFGFGQGVLAYFAVVIVYLGGFQAAKTIHN 1066
            :..:..|..|..:    |.:.....||:..|..|...|..|..|...|...:..|..:|::|:|.
Zfish   487 LAQDGVLCMWTGEAKEVQGLDGWKELRNSRLSAYALLGLLQAFLVCCAAYCLTCGSLKASRTLHT 551

  Fly  1067 ELLAVIIRGSVCRFFDITPI-------GRLLNSFSGDMDVVDEELPATMDSFMTFIFMVLATIVV 1124
            |||:.::.         .|:       .:|:.:.:.||.|:|||||..:.|.:..:..||:||.:
Zfish   552 ELLSDVLH---------LPVHSQKMNTRKLMQALTQDMQVIDEELPKHLHSILKSLLDVLSTITL 607

  Fly  1125 ISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGD 1189
            ||...|:|...:.|:..|....|....:|..|:..:|:          :..|:..|..|.....:
Zfish   608 ISFIIPVFSLAVCPMIILLLHIQSRISSTHMQIRNMEA----------NPAVSLTSLARVTQCAE 662

  Fly  1190 RFIEESDAKV----------DKNQVCKY-----PSVIANRWLAIRLEMVGNLIILFASLFAVLGG 1239
            ..:...:.:.          .:|.:.||     .|:....|:.:..:.|..:::|..||..:
Zfish   663 ASLSGPEHRAVCLKHCLQAFTQNLLLKYNTINTESICVCSWVVLWFDGVAGIVLLLVSLILL--- 724

  Fly  1240 QTNP--GLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPK 1302
            ||.|  |||.|::..:..:.:.|::..:.:|.|.|:::|::.:.:..:.::||.|.:  :...|.
Zfish   725 QTQPESGLVALTLICSFNIKEALHYCPQAASVITTDMLSLQNLFDSAKAEKEAEWTV--NYRPPY 787

  Fly  1303 NWPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGR 1367
            :|||.|.|:|:|::..........||||...|..|||:|:|.|.......|..:|||.:||..|.
Zfish   788 DWPQHGEVKFRNYESEASSDGTPALRGVHLTILKGEKIGVVSRQKTDTDVLINSLFRSVEARSGA 852

  Fly  1368 ISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSL 1432
            :.||.::|:.||||.||.||.||.|.||||||.||.|||||...:|.::|.||||.|||..|:.:
Zfish   853 LLIDNINISRMGLHDLRGRLQIISQVPVLFSGPLRANLDPFAEHSDAQVWLALELCHLKESVQQM 917

  Fly  1433 AAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFKECT 1497
            .|.|.|.:.......|.|||:|:|||||||.:.::|:::|....||.||:||:|:.|..|||:||
Zfish   918 PAQLLHPVQRTALAFSFGQRRLLCLARALLARVRILLVEEPLHHVDPETEDLLQQVIHAEFKDCT 982

  Fly  1498 VLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELL 1532
            ||.::....::|.:|:|:||||||.::|.:|:.||
Zfish   983 VLFLSQNPLSVLHTDRVLVLDKGQAVKFDAPSTLL 1017

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MRP	NP_723772.2	MRP_assoc_pro	14..1548	CDD:188098	321/1335 (24%)
abcc13	XP_073796816.1	None