Protein Alignment MRP and ABCC1

DIOPT Version :10

• Sequence 1: NP_723772.2
• Gene: MRP / 34686
• FlyBaseID: FBgn0032456
• Length: 1549
• Species: Drosophila melanogaster
• Sequence 2: XP_047290087.1
• Gene: ABCC1 / 4363
• HGNCID: 51
• Length: 1584
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 39/212 - (18%)
• Similarity: 80/212 - (37%)
• Gaps: 51/212 - (24%)

  Fly   606 YSGGSDSQLIQWQDVTESKRQQELDQRKDTLLQEQELSNLLSERKLLKALRLSL--------NLD 662
            :||..:..:.|.:||:...:::       |..|.:.::.|||.|..|.:|...:        :..
Human   265 FSGYREDNIPQLEDVSRFLKER-------TGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHAS 322

  Fly   663 RPLSTLK--IVNEVI--------RTKEQ-----GL------EDTVRKLSNDHKERLLRHAIEWNT 706
            .|:.:.:  ..:|::        ||..|     ||      ::.:.|||.     |....:|:..
Human   323 SPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLST-----LYWFTVEFGL 382

  Fly   707 NSKNCRPAQLALNVL-----LQETLAGRFQVSELNKHLEASLPYTERHFKR---LTEYVKDL--K 761
            ..:|.........:|     |...|:...::...:....|..||.::.::.   ::|...|.  |
Human   383 CKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDK 447

  Fly   762 FVEYSLRCMQPHAARMD 778
            ...|:.|..:|.:.:.|
Human   448 LRSYASRIQRPFSVKFD 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MRP	NP_723772.2	MRP_assoc_pro	14..1548	CDD:188098	39/212 (18%)
ABCC1	XP_047290087.1	MRP_assoc_pro	70..1583	CDD:188098	39/212 (18%)