Protein Alignment MRP and CG11898

DIOPT Version :10

• Sequence 1: NP_723772.2
• Gene: MRP / 34686
• FlyBaseID: FBgn0032456
• Length: 1549
• Species: Drosophila melanogaster
• Sequence 2: NP_651679.2
• Gene: CG11898 / 43451
• FlyBaseID: FBgn0039645
• Length: 1320
• Species: Drosophila melanogaster
• Alignment Length: 1383
• Identity: 461/1383 - (33%)
• Similarity: 725/1383 - (52%)
• Gaps: 188/1383 - (13%)

  Fly   218 QRGENEIPELSASFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHHWNQNVR 282
            ||..|  |...|:|.|:..:.|..::.:||.:..|:..||::..|....::|......||.|.::
  Fly     7 QRQPN--PVTKANFFSKWFFIWTREILVKGLQRNLDPSDLYETEPSLESTQVSSFLLGHWEQELK 69

  Fly   283 KNYKNKARVEPKAQFSNGNVTFENPHGEKNGRKKGMASIMPPIYKSFGGVFLFGALM-KLFTDTL 346
            ::..|..|:                                 |:|::|..|:..::: .:....:
  Fly    70 RSKPNVLRM---------------------------------IFKAYGWSFVPASIVYSIMAIAV 101

  Fly   347 TFAQPQVLSLIISFV-EAQDAEPEWKGILYAVLLFVLAAAQTFILGQYFH----RMFIVGLRIRT 406
            ...||.:|..::||. |:.....:....|||:.:.:.    :.|.|.:||    .:|.||.|:|.
  Fly   102 HTTQPLMLGGLVSFFSESTGKITKHSAYLYAMGVVLC----SLISGLFFHPFMKYLFRVGSRVRL 162

  Fly   407 ALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQL 471
            |....:|||.||:|.:.......|..::|||.|...|.|.....:.:|..||:..:.:|.::|.:
  Fly   163 ACAGLVYRKFLRVSVAADNSGVSGYAISLMATDLPTFNESFYCFHELWRGPLEGVVFVYIIYQLI 227

  Fly   472 GPSVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQ 536
            |...:.||..::..||:....|..|..|:.......|||||||||:::.::::|:||||.||.|.
  Fly   228 GWPAVVGLGTIVAFIPLQAWAARAIARYKRSSADVGDERVKLMNEIIAAMQLIKMYAWEKSFAKL 292

  Fly   537 VLDIRDKEIATLRSTAYLNAG---TSFLWSCAPFLVSLVTFATYVLTSEANQLSVEKVLVSIALF 598
            :..:|.:|:.::|.:.|:.||   |..:...:.|| |||   |||.|.:.  ::.:||.:..:.:
  Fly   293 IGKVRKEEMDSIRGSTYIYAGLQCTGMISKLSLFL-SLV---TYVFTGDI--VTSQKVFIVASYY 351

  Fly   599 DLMKLPLTILPMLSVDI-AETQVSVNRINKFLNSEELDPNSVLHD--SSKPHPMSIENGEF---- 656
            |.:...|.....|:::: .||.|..||:..||...|...:..:|:  .::.:|   |:|.|
  Fly   352 DHLNDSLLHSWPLAINMWVETFVVANRVKDFLFQHENPADGGVHNFKEAEDNP---EHGNFFGRT 413

  Fly   657 -----------------SWGDEIT------LRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEM 698
                             ||..:..      :.:::.:.:....|.:|||||:|||:::|..|||:
  Fly   414 HKPKAEVKSITVHKLSASWDQKKQEKRHRHIEDVSFQAQDQQFVGIVGTVGAGKSTLLQVILGEL 478

  Fly   699 EKLAGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRYNKVIDACALRADIDILSAGDLTE 763
            :.::|.|...|.|:|.||:.|:...::||||||.:.||.:||.:|:..|.|..|::.|..||.|.
  Fly   479 DIISGSVEVNGVLSYAPQEPWLLRGSLRDNILFTEPYDEQRYLEVLRVCHLDRDVEQLPLGDSTR 543

  Fly   764 IGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLV 828
            :||.|.:||||||.|:|||||||..||:|||||||||||:||.|.:.:..:..  .|::|.|:||
  Fly   544 VGEGGASLSGGQKARVSLARAVYRKADIYLLDDPLSAVDSHVSKMLLDRCLNE--FLSKKIRILV 606

  Fly   829 THGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAFADFIIQHLQEGNEEEEELNQIKRQISST 893
            ||.|..|..||.:.:::.|.||..|.:|.|.|                      |.:.:..:::.
  Fly   607 THRVQLLRHVDHLVLLEGGRISVQGHYDALKK----------------------LIRFRMSVAND 649

  Fly   894 ADVPELLGTVEKAIKLARTESLSDSISVTSADSLMGGGGSLRRRTKRQDSHDSVASAASLKKKQE 958
            .:|.:|        :..||:|:.:...              .|::..|:.|         ..:.|
  Fly   650 VEVAKL--------RAMRTDSVYEEPE--------------PRKSLSQEEH---------MDRHE 683

  Fly   959 VEGKLIETEKSQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVF-QAFQIGSNLWLTQWAN-DQNV 1021
            :|.:.  .|:.|.|.|:...||.|.|.:|..|.|..::|.||. ::.:...:::|::||. ::..
  Fly   684 IEQQF--KEQQQIGSVKLQTYKEYFKVLGHPLVVVLILLMFVVARSSEATMDIFLSKWATWEETE 746

  Fly  1022 AND---------TGLRDMYL-----------GVYGAFGFGQGVLAYFAVVIVYLGGFQAAKTIHN 1066
            .|.         |.||.|.|           .|...|||             ::...:.:..||:
  Fly   747 PNQHEPIPEYHRTRLRMMILYTFLILCTLIFYVLRTFGF-------------FMMTLRISLRIHD 798

  Fly  1067 ELLAVIIRGSVCRFFDITPIGRLLNSFSGDMDVVDEELPATMDSFMTFIFMVLATIVVISLSTPI 1131
            :|...:|| :...||.:...||:||.||.|:..:|..||..|...:.|....||.:.|:|.:...
  Fly   799 QLFQGVIR-AFMHFFTLATSGRILNRFSSDVLAIDVNLPQAMMDSIEFAVNALAVLAVVSTANIW 862

  Fly  1132 FLAVIVPIAFLYYFAQRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIE-ES 1195
            .|.....:..|.|..:..|:..||.|.|:|::||||||||.:.|..|.:||||.| |.:::| :.
  Fly   863 LLIPATVVVALLYGCRCLYIGASRSLKRIETISRSPIYSHTNATFKGLATIRALN-GTKYMERDF 926

  Fly  1196 DAKVDKNQVCKYPSVIANRWLAIRLEMVGNLIILFASLFAVLGGQTNPGL----VGLSVSYALQV 1256
            ....::|....|..|..||..|...:::..|.|| |..|:.|....:.|.    |||:::.::::
  Fly   927 HYYQNENTSALYLHVSINRAFAFWTDLICVLYIL-AVTFSFLLFDKHRGYYSGDVGLAITQSMKL 990

  Fly  1257 TQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYRE 1321
            .......:|.:.::|..:.||||:.||.....|..:|.|:..|.||:||..|:::|::.::||..
  Fly   991 VLMCQAGMRQTVELENMMTSVERVMEYVNIPSEPAYETEESVNLPKHWPSGGQLDFRDLRLRYSN 1055

  Fly  1322 GLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSR 1386
            ....:|:|::|.|:|.||:||||.|.|||||:..||||:.. ..|.|||||.:.:.:|||.||.|
  Fly  1056 HGPYILKGLTFTIRGEEKIGIVGHTAAGKSSIVHALFRLAH-INGHISIDGFETSQLGLHDLRRR 1119

  Fly  1387 LTIIPQDPVLFSGSLRINLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQ 1451
            ::||||||||||||||.||||||.|||:|:|.|||...||.||.:|..|:|..:.:.|.|.|:||
  Fly  1120 ISIIPQDPVLFSGSLRFNLDPFEEKTDEELWLALEAVKLKEFVSNLKDGINCRLHDCGANFSMGQ 1184

  Fly  1452 RQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIV 1516
            ||||||||||||:.|:|::|||||.||.|||:|||:.|.|:|..||||||||||:|::|:|:|:|
  Fly  1185 RQLVCLARALLRQNKILIMDEATANVDPETDNLIQEAIHTKFAHCTVLTIAHRLHTVMDNDRVMV 1249

  Fly  1517 LDKGQIIEFASPTELLDN 1534
            :|.|:::|...|.|||.|
  Fly  1250 VDMGRVVELGHPHELLHN 1267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MRP	NP_723772.2	MRP_assoc_pro	14..1548	CDD:188098	461/1383 (33%)
CG11898	NP_651679.2	MRP_assoc_pro	2..1268	CDD:188098	461/1383 (33%)