Protein Alignment MRP and rdog

DIOPT Version :10

• Sequence 1: NP_723772.2
• Gene: MRP / 34686
• FlyBaseID: FBgn0032456
• Length: 1549
• Species: Drosophila melanogaster
• Sequence 2: NP_651678.1
• Gene: rdog / 43450
• FlyBaseID: FBgn0039644
• Length: 1374
• Species: Drosophila melanogaster
• Alignment Length: 1416
• Identity: 456/1416 - (32%)
• Similarity: 724/1416 - (51%)
• Gaps: 202/1416 - (14%)

  Fly   216 KYQRGENEIPELSASFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHHWNQN 280
            |..|.:|  |...|:|.|:.::.|...:..:|.:.||.:::|:..|.......|...||..|...
  Fly     7 KVVRPKN--PFTKANFFSQWSFWWMRDLFKRGLQGPLTDEELYQHRKTLDSERVTNKFAELWEDE 69

  Fly   281 VRKNYKNKARVEPKAQFSNGNVTFENPHGEKNGRKKGMASIMPPIYKSFGGVFLFGALMKLFTDT 345
            ::::                     ||            |::..|.:::|.:|:...|....::|
  Fly    70 LKRS---------------------NP------------SVVRMILRAYGKIFVPMGLAFSISET 101

  Fly   346 LTFA-QPQVLSLIISFVEAQDAE-PEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTAL 408
            :..: .|..|..::.:......: .|....|||:.:.:...........:...:|.||.::|.||
  Fly   102 ICKSLMPLFLGGLVGYFATNQTDISENTAYLYAMGIVICMLVPVITFHPFIFYIFQVGTKLRLAL 166

  Fly   409 INAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGP 473
            ...||||.|::|.|:..:...|..:|:::.|..||.....:|:..|..|::..|..:.:::::|.
  Fly   167 SGLIYRKVLQVSKSSSNDGLRGRAINILSNDLGRFDVALCFLHDTWKGPMESILIGFLMYREIGI 231

  Fly   474 SVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVL 538
            |.:.|::.|:..||:....|.:...|:....:..|.|||||||::.||:|:|:||||.||.:.:.
  Fly   232 SAVIGVSFMLSFIPLQAWAAKKAAYYRQMTAERTDMRVKLMNEIIQGIQVIKMYAWEKSFARVIA 296

  Fly   539 DIRDKEIATLRSTAYLNAGTSFLWSCAPFLVSLVTFATYVLTSEANQLSVEKVLVSIALFDLMK- 602
            ::|.||:..:|.|||::|........:|..|.| ...:||...:  .|:.:||....:.|:::.
  Fly   297 EVRLKEVKAIRGTAYIHAALGCTSMISPLSVFL-ALCSYVYLGD--PLTAQKVYTVSSYFNMLND 358

  Fly   603 LPLTILPMLSVDIAETQVSVNRINKF------------------------------------LNS 631
            ..:|..||....|||..||..|...|                                    ||.
  Fly   359 SMVTFWPMSITFIAEALVSAKRCKDFLLDGDKAEVPINLEANQQTGKNKRKISKKDKQKNVELNG 423

  Fly   632 EELDPNSVLHDSSKPHP-------MSIENGEFSWGD-----EITLRNINIEVKKGSLVALVGTVG 684
            ..|....|.|:..:.:.       :.::|...||..     ...:.:.:.::|..:|.|:||.||
  Fly   424 SLLSNGQVHHNRLRDYDPEATKKCVVLKNVSASWDTSDGHANCAIEDFSTDIKDQTLAAVVGPVG 488

  Fly   685 SGKSSVVQAFLGEMEKLAGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRYNKVIDACAL 749
            :||||.:...|||:....|.....||::|..|::|:...|:||||:|.:.|:.:||.||:..|.|
  Fly   489 AGKSSFLNVLLGEVGIDKGEAMVHGKISYASQESWVFEGTIRDNIVFVEDYNERRYKKVVKVCGL 553

  Fly   750 RADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVI 814
            ..|:::|..||||.:||:|::||||||.|:|||||||..||:|||||||||||.|||||||:..|
  Fly   554 ERDMELLPRGDLTVVGERGVSLSGGQKARVSLARAVYRKADIYLLDDPLSAVDTHVGKHIFDRCI 618

  Fly   815 GPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAFADFIIQHLQEGNEE 879
              :..|:.|.|:||||.|.:|..|:.:.::..|:|...|::.:|.:::.      .|.|::...:
  Fly   619 --RDFLSNKIRILVTHQVQYLFDVEHLLLMGSGKIMAQGSYQELQRSRQ------FQFLEQTQHD 675

  Fly   880 EEELNQIKRQISSTADVPELLGTVEKAIKLARTESLSDSISVTSADSLMGGGGSLRRRTKRQDSH 944
            |..::                           |.|:|..:|.:.::..|            :..|
  Fly   676 ESGID---------------------------THSVSSYLSRSDSEKSM------------EHQH 701

  Fly   945 DSVASAASLKKKQEVEGKLIETEKSQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVFQAF----- 1004
            :.:     |:..:.||.  :..|:...|.::..||..|||::.     :|.:|..|...|
  Fly   702 NQL-----LRPDEHVED--VNQEQQTVGSIKMHVYASYIKALD-----STFLLGIVISLFVCARI 754

  Fly  1005 -QIGSNLWLTQWA-----------------NDQNVANDT---GLRDMYLGVYGA----FGFGQGV 1044
             ..|.:.:|::|.                 .|..:||||   ...|.|:....|    .|..|.:
  Fly   755 MLTGVDYFLSRWVIWEEQIAVNRTTTLLNETDTTIANDTLPINATDPYIAPLLASDIQAGIRQEL 819

  Fly  1045 LAYFAVV-----IVYL----GGFQAAKTI----HNELLAVIIRGSVCRFFDITPIGRLLNSFSGD 1096
            :.::|.:     ||||    |.|:....|    |:.|...|.|.|: .||:....||:||.||.|
  Fly   820 VLFYATILGATLIVYLIRTFGFFKMCLRISLHLHDRLFRGITRASM-YFFNTNSSGRILNRFSKD 883

  Fly  1097 MDVVDEELPATMDSFMTFIFMVLATIVVISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLE 1161
            :..||.:||.|:...:.||..|...:::::::....|.....|..:....:..||.|||.:.|||
  Fly   884 IRTVDTDLPHTLLDCLAFIIDVSGVVIIVAIANYWLLIPAAIIGVILGMIRYLYVNTSRSVKRLE 948

  Fly  1162 SVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVIANRWLAIRLEMVGNL 1226
            |:||||::|..::|..|.:||||........:|.....:.|....:..:...|..|:..::   |
  Fly   949 SISRSPVFSLTNQTFQGLTTIRALQAQSALEQEFHEYQNTNTSAWFLFLSCTRAFALWSDV---L 1010

  Fly  1227 IILFASL----FAVLGGQTNPGLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVERIKEYGETK 1287
            .|::.:.    |.:|..:.:.|.|||::.::..:|....|.:|.::::|..:.||||:.||.|..
  Fly  1011 CIVYMTAVTFSFLLLKDEFDSGDVGLAILHSTTMTGMCQWGMRQTAELENQMTSVERVLEYTEQP 1075

  Fly  1288 QEAPWELEQDKNKPKN-WPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGGEKVGIVGRTGAGKS 1351
            .||..| ..:|.|||: ||.:||:||.||::||......||:.::|.|:..||:|||||||||||
  Fly  1076 SEALLE-TPEKFKPKSEWPSKGRIEFINFKLRYSPKEAPVLKDLNFTIEPREKIGIVGRTGAGKS 1139

  Fly  1352 SLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLDPFEIKTDDEI 1416
            |:..::|| :....|.|.||.|||..:|||.|||:::|||||||||||:||.||||.:.::|:|:
  Fly  1140 SIIQSIFR-LACNEGMIRIDDVDIEHIGLHDLRSQVSIIPQDPVLFSGTLRYNLDPMDERSDEEM 1203

  Fly  1417 WKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLET 1481
            ||||....|:|:|.:|..|||..:.:||.|.|||||||||||||:||..|:|::|||||.||.||
  Fly  1204 WKALGDVELRSYVSTLIGGLNCRMYDGGSNFSVGQRQLVCLARAILRHNKILIMDEATANVDPET 1268

  Fly  1482 DDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELL 1532
            |.|||:|||::|..||||||||||:|::|||:|:|:|.|::.|...|.|||
  Fly  1269 DKLIQQTIRSKFAHCTVLTIAHRLHTVMDSDRVLVMDAGEVRELGHPYELL 1319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MRP	NP_723772.2	MRP_assoc_pro	14..1548	CDD:188098	456/1416 (32%)
rdog	NP_651678.1	MRP_assoc_pro	14..1323	CDD:188098	453/1407 (32%)