Protein Alignment MRP and CG9270

DIOPT Version :10

• Sequence 1: NP_723772.2
• Gene: MRP / 34686
• FlyBaseID: FBgn0032456
• Length: 1549
• Species: Drosophila melanogaster
• Sequence 2: NP_995741.2
• Gene: CG9270 / 35366
• FlyBaseID: FBgn0032908
• Length: 1292
• Species: Drosophila melanogaster
• Alignment Length: 1372
• Identity: 487/1372 - (35%)
• Similarity: 731/1372 - (53%)
• Gaps: 170/1372 - (12%)

  Fly   225 PELSASFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSCSEVMPIFAHHWNQNVRKNYKNKA 289
            |..||...|.:.:.:...:..||.:..||..||::...:.....:...|...|...||
  Fly    10 PRESAGIFSTLMFCFALPILFKGRKKTLEPTDLYNALKEHKAETLGDKFFATWQSEVR------- 67

  Fly   290 RVEPKAQFSNGNVTFENPHGEKNGRKKGMASIMPPIYKSFG----------GV----------FL 334
                    |.|:...:.|            ||:..|.|.||          ||          .:
  Fly    68 --------SCGDSPKKEP------------SIIRVILKVFGWQLFLSGIVVGVLELGTRATLPLI 112

  Fly   335 FGALMKLFT-----DTLTFAQPQVLSLIISFVEAQDAEPEWKGILYAVLLFVLAAAQTFILGQYF 394
            .|||:..||     |.| :||...|:||:|             ||::||:|     ...::|
  Fly   113 LGALIAEFTRNGNGDGL-WAQIYGLTLILS-------------ILFSVLMF-----HPLMMG--- 155

  Fly   395 HRMFIVGLRIRTALINAIYRKALRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQ 459
              :..:.:::|.|:..||||||||:|.:...::|.|::|||::.|..||.....:.:.:|..||:
  Fly   156 --LMHLAMKMRVAVSTAIYRKALRLSRTALGDTTTGQVVNLISNDLGRFDRALIHFHFLWLGPLE 218

  Fly   460 IGLALYFLWQQLGPSVLAGLAVMIILIPVNGVIASRIKTYQIRQMKYK-DERVKLMNEVLSGIKV 523
            :.::.|||:||:|.:.|.|:.::::.:|:. ...||:.:....|...: |:||::|||::|||:|
  Fly   219 LLISSYFLYQQIGVASLYGIVILLLFLPIQ-TFLSRLTSRLRHQTALRTDQRVRMMNEIISGIQV 282

  Fly   524 LKLYAWEPSFEKQVLDIRDKEIATLRSTAYLNAGT--SF--LWSCAPFLVSLVTFATYVLTSEAN 584
            :|:|.||..|.:.:..:|..|::::|...|:. ||  ||  ..|.....|||:.|...     ..
  Fly   283 IKMYTWEKPFGRLIERLRRSEMSSIRKVNYIR-GTLLSFEITLSRIAIFVSLLGFVLM-----GG 341

  Fly   585 QLSVEKVLVSIALFDLMKLPL-TILPMLSVDIAETQVSVNRINKFLNSEELD--------PNSVL 640
            :|:.|:.....|.:::::..: ...|......||..|::.||..|:...|.:        .|.:.
  Fly   342 ELTAERAFSVTAFYNILRRTVCKFFPSGMSQFAEMMVTLRRIKGFMMRSETEALYLKGGQTNKLF 406

  Fly   641 HDSSKPHPM-SIENGEFSWGD---EITLRNINIEVKKGSLVALVGTVGSGKSSVVQAFLGEMEKL 701
                :..|: .:::.:..|..   |..|.||||.:....|||::|.|||||||::||.|||:...
  Fly   407 ----EGEPLVKLQSFQARWNHDHVEPVLENINISLSPPQLVAVIGPVGSGKSSLIQAILGELPGE 467

  Fly   702 AGVVNTVGKLAYVPQQAWIQNATVRDNILFGQTYDRKRYNKVIDACALRADIDILSAGDLTEIGE 766
            :|.:...|.::|..|:.|:.||:||||||||...|:.||..||..|||..|.::|. ||.|.:||
  Fly   468 SGKLKVQGDISYASQEPWLFNASVRDNILFGLPMDKHRYRNVIRNCALERDFELLH-GDRTFVGE 531

  Fly   767 KGINLSGGQKQRISLARAVYSDADLYLLDDPLSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHG 831
            :|.:|||||:.|||||||||..||.|||||||||||.|||:|:|||.:  :|.|..|..:||||.
  Fly   532 RGASLSGGQRARISLARAVYRQADTYLLDDPLSAVDTHVGRHLFEECM--RGFLRDKLVILVTHQ 594

  Fly   832 VTFLPQVDSIYVIKMGEISESGTFDQLVKNKGAFADFIIQHLQE-GNEEEEELNQ--IKRQISST 893
            :.||...|.|.::..|:||..||:::::|:...|...:....|| |:..:|::|.  ..|...||
  Fly   595 LQFLEHADLIVIMDKGKISAVGTYEEMLKSGQDFGKLLATEAQEMGDSNQEQVNAEGDSRNDKST 659

  Fly   894 ADVPELLGTVEKAIKLARTESLSDSISVTSADSLMGGGGSLRRRTKRQDSHDSVASAASLKKKQE 958
                           .:|..|....:||||.||                |.:|:..    .::|.
  Fly   660 ---------------YSRQSSRVSRVSVTSVDS----------------STESILD----NERQP 689

  Fly   959 VEGKLIETEKSQTGGVEFAVYKHYIKSVGIFLSVATLVLNFVF--QAFQIGSNLWLTQWANDQNV 1021
            .:      |....|.:...:|..|. |.|....:..||..|..  |....|.:.:|:.|..:.:.
  Fly   690 AQ------ESRSQGKIGLGIYGKYF-SAGSGWLMVILVAFFCLGTQILASGGDYFLSYWVKNNDS 747

  Fly  1022 ANDTGLRDMYLGVYGAFGFGQGVLAYFAVVIVYLGGFQAAKTIHNELLAVIIRGSVCRFFDITPI 1086
            ::.|   |:|  ::........:.|....::.:.....::..:||.:...:.| :...||...|.
  Fly   748 SSST---DIY--IFSGINAALVIFALLRTLLFFSMAMHSSTQLHNTMFQGVSR-TALYFFHANPS 806

  Fly  1087 GRLLNSFSGDMDVVDEELPATM-DSFMTFIFMVLATIV-VISLSTPIFLAVIVPIAFLYYFAQRF 1149
            ||:||.|:.|:..|||.|||.| |...  ||:.::.|: |:.::.|.:|...:.:...::|.:.|
  Fly   807 GRILNRFAMDLGQVDEILPAVMLDCIQ--IFLTISGIIGVLCITNPWYLINTITMFLAFHFLRTF 869

  Fly  1150 YVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVIANR 1214
            |::|||.|.|||:::|||:|||||.|:.|.|||||....|...:|.|...|.:....|..:..||
  Fly   870 YLSTSRDLKRLEAIARSPMYSHFSATLNGLSTIRAMEAQDLLTKEYDNYQDIHSSGYYTFLSTNR 934

  Fly  1215 WLAIRLEMVGNLIILFASLFAVLGGQT-NPGLVGLSVSYALQVTQTLNWLVRMSSDIETNIVSVE 1278
            .....|::.....::..:|.:...... |||.:||.::.|:.:|.|:.|.:|.|:::|.::.|||
  Fly   935 AFGYYLDLFCVAYVISVTLMSYFNPPVDNPGQIGLVITQAMSMTGTVQWGMRQSAELENSMTSVE 999

  Fly  1279 RIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYREG--LDLVLRGVSFNIQGGEKVG 1341
            |:.||...:.|..:|...||..|.||||||.:..:...:||...  .|.||:.::|.|...||:|
  Fly  1000 RVLEYRHLEAEGEFESPDDKKPPMNWPQEGLISAEQLSLRYNPDPKADRVLKSLNFIIMPREKIG 1064

  Fly  1342 IVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLRINLD 1406
            ||||||||||||..||||:....|..: ||..||..:|||.|||:::||||:||||||:||.|||
  Fly  1065 IVGRTGAGKSSLINALFRLSYNEGSLV-IDNTDILGIGLHDLRSKISIIPQEPVLFSGTLRCNLD 1128

  Fly  1407 PFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKVLVLD 1471
            |||...|:::|:|||..|||..|..|..||...:||||.|.|||||||||||||:||:.::||:|
  Fly  1129 PFEQYADEKLWEALEEVHLKDEVSELPNGLESVVAEGGSNYSVGQRQLVCLARAILRENRILVMD 1193

  Fly  1472 EATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELLDNPK 1536
            ||||.||.:||.|||.|||.:|::|||||||||||||:|||:|:|||.|.::||.||.|||....
  Fly  1194 EATANVDPQTDALIQSTIRRKFRDCTVLTIAHRLNTIIDSDRVMVLDAGTLVEFGSPFELLTQSW 1258

  Fly  1537 S-AFYSM 1542
            | .||.|
  Fly  1259 SKVFYGM 1265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MRP	NP_723772.2	MRP_assoc_pro	14..1548	CDD:188098	487/1372 (35%)
CG9270	NP_995741.2	PLN03130	10..1289	CDD:215595	487/1372 (35%)