|
Fly 11 RFCGSTFWNATETWYTNDPDFT-PCFEQTALVWTPCAFYWAFVIFDFYYLKASLDRNI--PWN-- 70
:.||:........| :.|.| .||.|..|...|.|. ..:....:|......|| |:|
Rat 7 QLCGTDAARPLPLW---EGDTTGHCFTQLVLSVLPHAL---LAVLSACHLGTPRTNNIIQPFNPG 65
Fly 71 -KLNVSKALVNLGLLVITALDL---IMALVKKGGDSELPL------------YDLDVW------- 112
:|.::.:.: |.|...||| ::..|...|...|.: :.|.:|
Rat 66 WRLRLTASFL---LSVFPLLDLLPVVLPPVSHPGPLWLEVLAGCVTAVAWFTHSLALWALVHSPH 127
Fly 113 ----GPIIKFATFLLLFIFIPLNRKYGVQTTGCQFIFW------FLLTVLSIPR---CRTEVRLD 164
||:. |.|..|:|.... |.| :.| ||..:|..|. |...::|.
Rat 128 GHSRGPLA-----LALAAFLPTPAL--VLT-----LLWHCQRGTFLPPLLPGPLGRVCLLILQLA 180
Fly 165 AERQKILNSQQPSEQDFSWEEYQFVSFFIFFTFTSIMLILNCFADGMPRQTKYQRGENEIPELSA 229
|.....|....|......|....|:| | :..|.|:.|...
Rat 181 AVLAYGLGWAAPGGPREPWTHDPFLS---------------------P-----ESQEREVAEDGE 219
Fly 230 SFLSRITYQWFDKMALKGYRNPLEEKDLWDLRPQDSC--------SEVMPIFAHHWNQNVRKNYK 286
|:|||.:|.|...:..:|.|..|.: |||:| :.:...|..||
Rat 220 SWLSRFSYAWLAPLLARGVRGELRQ-------PQDTCRLPRRLHPAYLARAFQAHW--------- 268
Fly 287 NKARVEPKAQFSNGNVTFENPHGEKNGRKKGMASIMPPIYKSFGGVFLFGALMKLFTDTLTFAQP 351
|:| |.:...:|.:||..::...|:|:....|.|:.|
Rat 269 ----------------------------KEG-AQLWRALYGAFGCCYIALGLLKMVGTMLGFSGP 304
Fly 352 QVLSLIISFVEAQDAEPEWKGILYAVLLFVLAAAQTFILGQYFHRMFIVGLRIRTALINAIYRKA 416
.:|||::.|:| :..||...|:||.:.|...:.....:..||.:.:..|.|:.|.|:::.:|||.
Rat 305 LLLSLLVGFLE-EGQEPLSHGLLYVLGLASGSVISAVLQNQYGYEVRKVTLQARVAVLSILYRKT 368
Fly 417 LRISNSTKKESTVGEIVNLMAVDAQRFMELTTYLNMIWSAPLQIGLALYFLWQQLGPSVLAGLAV 481
|::..| ....||::||:..|::|.:......:..|..|||:.:.||.|::|:|.:.||||.:
Rat 369 LKLGPS---RPPTGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYEQVGVAFLAGLVL 430
Fly 482 MIILIPVNGVIASRIKTYQIRQMKYKDERVKLMNEVLSGIKVLKLYAWEPSFEKQVLDIRDKEIA 546
.::|:|||.|||:||.......:::||.|||||.|:||||:|||.:.||.:...:|...|.:|:.
Rat 431 ALLLVPVNKVIATRIMANNQEMLRHKDARVKLMTELLSGIRVLKFFRWEQALGDRVKACRTQELG 495
Fly 547 TLRSTAYLNAGTSFLWSCAPFLVSLVTFATYVLTSEANQLSVEKVLVSIALFDLMKLPLTILPML 611
.||...||:|...:||:..|.::.:|.|.||||. .:||:..||..::||..::.|||...|.:
Rat 496 RLRVIKYLDAACVYLWAALPVVICIVIFITYVLL--GHQLTATKVFTALALVHMLILPLNNFPWV 558
Fly 612 SVDIAETQVSVNRINKFLNSEELDPNSVLHDSSKPHP---MSIENGEFSWGDEITLRNI---NIE 670
...:.|::||::||.:||:.....|.:.........| :.:....|||....|.:.. :::
Rat 559 INGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPTEPSTVLELHEALFSWDPTGTSQKTFISHLQ 623
Fly 671 VKKGSLVALVGTVGSGKSSVVQAFLGEMEKLAG--VVNTVGK-LAYVPQQAWIQNATVRDNILFG 732
||||.||.:||.||.||||::.|..||:.:|.| .|:.:.| .....|:.|||.||:|||:|||
Rat 624 VKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVSDLSKGFGLATQEPWIQCATIRDNVLFG 688
Fly 733 QTYDRKRYNKVIDACALRADIDILSAGDLTEIGEKGINLSGGQKQRISLARAVYSDADLYLLDDP 797
:|:|.:.|.:|::||||..|:.||.|||.||:||||:.|||||:.||:||||||.:..|||||||
Rat 689 KTFDAQLYREVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKTLYLLDDP 753
Fly 798 LSAVDAHVGKHIFEEVIGPKGILARKSRVLVTHGVTFLPQVDSIYVIKMGEISESGTFDQLVKNK 862
|:||||.|..|:....| .|:|...:|:|.||...:|.:.|.:.:::.|.:..:|
Rat 754 LAAVDADVANHLLHRCI--LGVLGHTTRLLCTHRTEYLERADLVLLMEAGRLVRAG--------- 807
Fly 863 GAFADFIIQHLQEGNEEEEELNQIKRQISSTADVPELLGTVEKA-IKLARTESLSDSISVTSADS 926
...|:|..|:.| ..||..|.::||
Rat 808 --------------------------------PPSEILPLVQAAPTALADKEQVTDS-------- 832
Fly 927 LMGGGGSLRRRTKRQDSHDSVASAASLKKKQEVEGKLIETEKSQTGGVEFAVYKHYIKSVGIFLS 991
|...|: |:...:...|...|...|:|::.|....|.|...||:.|.:::|..|:
Rat 833 --GQSPSV---------HNLEKTTEELDVAQNTSGRLVQEESKSEGAVALHVYRAYWRAMGSGLA 886
Fly 992 VATLVLNFVFQAFQIGSNLWLTQWANDQNV----------------------------------- 1021
.|.|:...:.||.:.|::.||..|.:....
Rat 887 TAILISLLLMQATRNGADWWLAHWLSQLKAGRNSSEERPASSSPRSMGFFSPRLLLFSPGNLYIP 951
Fly 1022 ---ANDTGLRDM--YLGVYGAFGFGQGVLAYFAVVIVYLGGFQAAKTIHNELLAVIIRGSVCRFF 1081
|...|..|: ||.||........:......|:...|..|||.::|:.||..::...| .|:
Rat 952 LHKATSNGSSDVHFYLTVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPV-TFY 1015
Fly 1082 DITPIGRLLNSFSGDMDVVDEELPATMDSFMTFIFMVLATIVVISLSTPIFLAVIVPIAFLYYFA 1146
|.||.||:||.||.|:..||:.||..::..:.....:|..:.|:....|..|.::.|::|:||..
Rat 1016 DSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFIYYGV 1080
Fly 1147 QRFYVATSRQLMRLESVSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAKVDKNQVCKYPSVI 1211
||.|.|:.|:|.||.|::.||:|||.::|:.|...:||.....||.||:...::.||.|::.|..
Rat 1081 QRRYRASFRELRRLGSLTLSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYA 1145
Fly 1212 ANRWLAIRLEMVGNLIILFASLFAVL---GGQTNPGLVGLSVSYALQVTQTLNWLVRMSSDIETN 1273
..:||.|||:::|..::...:..|:: .|..|||||||.:||||.:|..|:.||...:..|..
Rat 1146 TMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSFTQTEAM 1210
Fly 1274 IVSVERIKEYG-ETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYREGLDLVLRGVSFNIQGG 1337
:|||||::||. :..||...:..|..::..:|..:|.||||:..:.||.||...|.||:|.::.|
Rat 1211 MVSVERLEEYSCDIPQEPHGQPPQSPHQRVSWLTQGSVEFQDVVLVYRPGLPNALDGVTFRVEPG 1275
Fly 1338 EKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRSRLTIIPQDPVLFSGSLR 1402
||:|||||||:|||||.|.|||::|.:.|::.:||||.:.:.|..|||:|.:|||:|.||||::|
Rat 1276 EKLGIVGRTGSGKSSLFLVLFRLLEPSAGQVLLDGVDTSQLELAELRSQLAVIPQEPFLFSGTVR 1340
Fly 1403 INLDPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGENLSVGQRQLVCLARALLRKTKV 1467
.||||..:..|..:|:|||..|| |.|.....||:.|:.|.|.:||:|||||:|||||||...|:
Rat 1341 ENLDPQGLHEDRALWQALEQCHL-SEVAMAIGGLDGELGERGRDLSLGQRQLLCLARALLTDAKI 1404
Fly 1468 LVLDEATAAVDLETDDLIQKTIRTEFKECTVLTIAHRLNTILDSDKVIVLDKGQIIEFASPTELL 1532
|.:|||||:||.:||.|:|:||...|...|||||||||||||:||:|:||..|:::|..||:.|.
Rat 1405 LCIDEATASVDQKTDQLLQQTICRRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALR 1469
Fly 1533 DNPKSAFYSMAKDA 1546
:.|.|.|..:.:.:
Rat 1470 NQPHSLFRQLLQSS 1483
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