Protein Alignment MRP and haf-1

DIOPT Version :9

• Sequence 1: NP_723772.2
• Gene: MRP / 34686
• FlyBaseID: FBgn0032456
• Length: 1549
• Species: Drosophila melanogaster
• Sequence 2: NP_503098.2
• Gene: haf-1 / 178522
• WormBaseID: WBGene00001811
• Length: 677
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 140/599 - (23%)
• Similarity: 260/599 - (43%)
• Gaps: 105/599 - (17%)

  Fly   973 GVEFAVYKHYIKSVGIFLSVATLVLNFVFQAFQIGSNLWLTQWANDQNVANDTGLRDMYLGVYGA 1037
            |..|.|.     |.|||| :...:|..:...|...:.:...:......:|.  ..::..:.:.|.
 Worm    88 GTSFMVV-----SSGIFL-IIPRILGKLIDQFDSNTGVQKAEEVFTMKIAK--YFKEQPMSLVGL 144

  Fly  1038 FGFGQGVLAYFA-VVIVYLGGFQAAKTIHNELLAVIIRGSVCRFFDITPIGRLLNSFSGDMDVVD 1101
            ...  |.||..| |..:.:.|.....::...:.:.|||..: .|||...:|.:.:..:.|..:|.
 Worm   145 LAI--GALATAAKVYCLQIAGVNIVGSLRKMVYSSIIRQDM-TFFDKNMVGEIGSRHAADTVIVG 206

  Fly  1102 EELPATMDSFMTFIFMVLATI-----VVISLSTPIFLAVIVPIAFLYYFAQRFYVATSRQLMRLE 1161
            ..:.:::.:.:..:.:.:.:|     ..:.|||..||...:.:.....|. |.....:.||..:.
 Worm   207 YSVSSSLRAGVRAVLVGVGSIGMMLMTSLELSTVSFLTAPIVMGIFKMFG-RVQQQCTWQLQEVA 270

  Fly  1162 S-VSRSPIYSHFSETVTGASTIRAYNVGDRFIEESDAK------VDKNQVCKYPSVIANRWLAIR 1219
            : |:::.|     |.:....|||..:...:.|:|...|      :.|.:.....|:|.:
 Worm   271 ADVNQTAI-----ERMANMKTIRMLSAEQQSIDEYCKKGELVLDISKTEALAKGSLIGS------ 324

  Fly  1220 LEMVG----NLIILFAS-----------------LFAVL--------GGQTNPGLVGLSVSYALQ 1255
            .:..|    :.|:.:.|                 |:|||        .|..|..:.||..|..|.
 Worm   325 FQFTGYSAFSSILFYGSHLINTGHITYGELSSFCLYAVLAAASLSNISGFYNEVMKGLGASSRLL 389

  Fly  1256 VTQTLNWLVRMSSDIETNIVSVERIKEYGETKQEAPWELEQDKNKPKNWPQEGRVEFQNFQVRYR 1320
            ..:....::.::|.|:...::..                               ::|:|....|
 Worm   390 ELKNAQPIMNLNSGIKKTDITTS-------------------------------IQFENVSFAY- 422

  Fly  1321 EGLDLVLRGVSFNIQGGEKVGIVGRTGAGKSSLTLALFRIIEAAGGRISIDGVDIASMGLHMLRS 1385
            .|....|..:||:|..|:...::|.:|:||||:...:.|:.:.|.||:::||||:..:.....|.
 Worm   423 AGRKKTLENISFDIPRGKITAVIGPSGSGKSSIANLMLRLYDPADGRVTVDGVDLRDLNATTWRH 487

  Fly  1386 RLTIIPQDPVLFSGSLRINL-----DPFEIKTDDEIWKALELSHLKSFVKSLAAGLNHEIAEGGE 1445
            .:..:.|:||||:.|:|.|:     .|.:: :..|:.:|.:|::...|::....|....:.|.|.
 Worm   488 AIGTVGQEPVLFTCSIRENILMGTEHPEKV-SQYELEEAAQLANALDFIQGFENGFETMVGEHGC 551

  Fly  1446 NLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQKTIRTEFK--ECTVLTIAHRLNTI 1508
            .||.||:|.:.:||||:.|.|:::|||||:|:|..:|.||:.|:....|  ..|||.|||||.|:
 Worm   552 KLSGGQKQRIAIARALISKPKIMILDEATSALDATSDYLIRMTLDNLLKNHNLTVLVIAHRLATM 616

  Fly  1509 LDSDKVIVLDKGQI 1522
            ..:|:|:.:::|:|
 Worm   617 QQADQVVYVNRGRI 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MRP	NP_723772.2	MRP_assoc_pro	14..1548	CDD:188098	140/599 (23%)
		ABC_membrane	338..601	CDD:279056
		ABCC_MRP_domain1	649..848	CDD:213217
		ABC_membrane	988..1260	CDD:279056	57/313 (18%)
		ABCC_MRP_domain2	1308..1528	CDD:213211	76/222 (34%)
haf-1	NP_503098.2	MdlB	82..641	CDD:224055	140/599 (23%)
		ABC_membrane	93..363	CDD:294371	52/292 (18%)
		P-loop_NTPase	413..641	CDD:304359	76/220 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910