Protein Alignment Pih1D1 and Dnaaf2

DIOPT Version :9

• Sequence 1: NP_723771.4
• Gene: Pih1D1 / 34685
• FlyBaseID: FBgn0032455
• Length: 1094
• Species: Drosophila melanogaster
• Sequence 2: NP_081545.3
• Gene: Dnaaf2 / 109065
• MGIID: 1923566
• Length: 814
• Species: Mus musculus
• Alignment Length: 777
• Identity: 139/777 - (17%)
• Similarity: 220/777 - (28%)
• Gaps: 327/777 - (42%)

  Fly   426 SNQQPNLDRNAISDDGIQLPRDRFRSPEAHPKQPPYPRNVNADQVGNRGPQKRHNYQRIVNDNQI 490
            |:...:||   :|.:.:|.....|:.||.......|...:.       .|:.|..|
Mouse     7 SSALEDLD---LSREEVQRFTSAFQDPEFRRMFSEYAAEIT-------DPENRRRY--------- 52

  Fly   491 ILRRTDWTDEEEDLDLEHH---DIDDYIPDEREFLEDDAD-----FIDDTNDTLMNDDQYEGYHS 547
                     |||...||..   |:....|:....|....|     :::..:::|:..........
Mouse    53 ---------EEEITALERERGVDVRFVHPEPGHVLRTSLDGEHRCYVNVCSNSLVGVPSSRPGPG 108

  Fly   548 RG----NQHYIQDHNIDDRNSY-GRN-------------------RNDRNF---------EGIRR 579
            ||    ..|:...:::.....| |||                   |:...|         |.:.:
Mouse   109 RGGTAAGSHWSLPYSLAPGRQYAGRNGARYTVYDVVFHPEALALARSHERFREMLDATALEAVEQ 173

  Fly   580 QFDPELDRRNLNDNFNQRNNYS------------RGGDTVR--------FPRREDDTFQGSNNPN 624
            ||...|||||..   ..:..|.            .||...:        ||           :|.
Mouse   174 QFGVRLDRRNAK---TLKIKYKGMPEAAVLRTPLPGGVPAQPEGEPPGLFP-----------DPP 224

  Fly   625 FPPNYPNTILRGSGSGNRCRDTSSNRPMG-----PNQNRRSRLPN----------ADEAAPS-VA 673
            :|..||     .:.:.|..|..:|..|..     |.:.|.|.:..          :.:|||| |.
Mouse   225 YPYRYP-----AAAAANTARSPASPAPEAVQRPEPTEPRCSVVQRHHVDLQDYRCSRDAAPSTVP 284

  Fly   674 HS--------------------GGPI--QDGTNLNRRINKNL----NPGKGPDRIN--------- 703
            |.                    .|.:  .|..|.:.|:..:|    :.|:|..:.|
Mouse   285 HELVVTIELPLLRSVERAELEVKGKLLCLDSRNPDYRLRLSLPYPVDDGRGKAQYNKARRQLVVT 349

  Fly   704 -------------AGTPNQPRSKSTTSQTRNLNPDIPNKMVKKSAVPQDNRAPQPNKPMNTNPGA 755
                         |.||.:|..::.|.       |:........|..::..|...........|.
Mouse   350 LPVALADARQEPPAATPEEPAEETGTD-------DVARTSAGDFAAAREESADGTGADHGEKSGV 407

  Fly   756 SKP--------GQSVIKPKLQATKINAAMAKPLAGIKRKAETTPKLGGATKAGPKRQRADRTDRS 812
            ..|        |:.|.:|:   .........||           .||..|..|         ||
Mouse   408 GAPDPGAAHAEGELVPEPE---QDFGGDSVAPL-----------DLGKGTSPG---------DR- 448

  Fly   813 FIIGGISLPYINSNTKKLPQPEEQSYAVTFFEQTPNYNTNIYAIDDGHVDEDE-----------G 866
                  ||||     ...|..:.:|..     ..|...||         :|.|           |
Mouse   449 ------SLPY-----SAFPGGDTESLC-----GDPGVQTN---------EEQERTRHDTAGSAMG 488

  Fly   867 DGDDEEMS----------DAESL------------------------------DSNRSGVLSKWK 891
            |...|.::          |.:||                              ||..|..|.
Mouse   489 DPGTESIAPVCPPLQCNQDEDSLTLLIQVPGILPQTLHGHLSPVGYELCFSTQDSGYSCTLQ--- 550

  Fly   892 GRSSKKKVRTQLRKEWTKIYRTN------NYKDWHAWWRDFKWCGSEINKKLEKFGDRNLRHRFA 950
             .:.:.|:.|  |:..|.:...|      ...:.|..||:: :||  :||:       :|..|.
Mouse   551 -FAPENKLST--REPETSVSLNNAVIVLAKSPESHGLWREW-YCG--LNKE-------SLEERL- 601

  Fly   951 PIGRKPMTGKTINQIFKSGHMGLEKNTFSHYRNMRSIFLLMNEKFLNSLSDEQLE---QLQD 1009
                      .||:...:|.  ||:...|..:..||:...:.|  :...:|||::   :||:
Mouse   602 ----------FINEENVNGF--LEEVLCSPLKQARSLAPPLIE--VLQATDEQVQIHAELQE 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pih1D1	NP_723771.4	PHA02896	<406..620	CDD:165222	44/254 (17%)
Dnaaf2	NP_081545.3	PIH1	43..352	CDD:285409	60/352 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..259		5/24 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	357..490		33/188 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	654..686

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4356
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4625
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930