Protein Alignment spict and Nipal3

DIOPT Version :10

• Sequence 1: NP_001260421.1
• Gene: spict / 34681
• FlyBaseID: FBgn0032451
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001334149.1
• Gene: Nipal3 / 74552
• MGIID: 1921802
• Length: 418
• Species: Mus musculus
• Alignment Length: 353
• Identity: 104/353 - (29%)
• Similarity: 178/353 - (50%)
• Gaps: 46/353 - (13%)

  Fly     4 DG-EASSLQMPQVTVGGMLPVEANQSPETAPLSMAE-TVSNTDFYIGVGLAISSCFFIGSSFIIK 66
            || .::.||:.        |:.......:..||.:| :.|..:..||..|||.....:..:..::
Mouse     2 DGAHSAGLQLQ--------PLPPTSGATSTSLSSSEGSFSYKENLIGALLAIFGHLVVSIALNLQ 58

  Fly    67 KKALIRLSRYGEVRASAGGFGYLREWIWWAGLLTMGVGEAANFAAYAFAPASLVTPLGALSVIIS 131
            |...|||:...:.||      |.:...||.|||.:.:||...||:|||||.||:.||.|:|||.|
Mouse    59 KYCHIRLAGSKDPRA------YFKTKTWWLGLLLLLLGELGVFASYAFAPLSLIVPLSAVSVIAS 117

  Fly   132 AVMASRFLNEKLN--------LLGKIGCFLCILGSTIIVIHSPKEKEIEDLQLLFDMLLDPVFIL 188
            |::...|:.||..        :|..:||.|.|:|:.::|..:|...|....:.:...|:...|:|
Mouse   118 AIIGIIFIKEKWKPKDFVRRYVLSFVGCGLAIVGTYLLVTFAPNSHEKMTGENIARHLVSWPFLL 182

  Fly   189 YVICIVGSTVFVACFIAPRHGHTNVVVYIFLCSGIGSLTVMSCKAL-GLAIRQTLNNGGNVFLTW 252
            |::..:.....:..|...|:.: ::||.:.|.:.:||:||::.||: |:.:   |:..||:.|.:
Mouse   183 YMLVAIVLFCLLLYFYKERNAN-SIVVILLLVALLGSMTVVTVKAVSGMLV---LSIQGNLQLDY 243

  Fly   253 MPWFLILVTVTFIAI-QMNYLNKALDIFNTSIVTPVYYVMFTTLVIAASAILFKEFTHMRFDDIL 316
            ..::::.|.:...|| |..:|::|..|:::|::..|.|::.||..|.|.||.:.:|        |
Mouse   244 PIFYVMFVCMVATAIYQATFLSEASQIYDSSLIASVGYILSTTAAITAGAIFYLDF--------L 300

  Fly   317 GD----VC----GFLIVITAVFLLNAFR 336
            |:    :|    |.||....|||:...|
Mouse   301 GEEALHICMFALGCLIAFLGVFLITRNR 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spict	NP_001260421.1	Mg_trans_NIPA	43..338	CDD:398984	95/312 (30%)
Nipal3	NP_001334149.1	EamA	36..330	CDD:474045	95/311 (31%)