Protein Alignment spict and Nipal2

DIOPT Version :10

• Sequence 1: NP_001260421.1
• Gene: spict / 34681
• FlyBaseID: FBgn0032451
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_663444.2
• Gene: Nipal2 / 223473
• MGIID: 1924488
• Length: 383
• Species: Mus musculus
• Alignment Length: 360
• Identity: 104/360 - (28%)
• Similarity: 170/360 - (47%)
• Gaps: 35/360 - (9%)

  Fly    29 PETAPLSMAETVSNTDFYIGVGLAISSCFFIGSSFIIKKKALIRLSRYGEVRASAGGFGYLREWI 93
            |....||.|....|.....||.|||.....|..|..|:|.:.:.|::....:.      |.:..:
Mouse    31 PGNGSLSSAWYRRNQIHLFGVLLAILGNLVISISLNIQKYSHLHLAQKEHPKP------YFKSVL 89

  Fly    94 WWAGLLTMGVGEAANFAAYAFAPASLVTPLGALSVIISAVMASRFLNEKLNLLGKIGCFLCILGS 158
            |.:|:|...:||..|||||..||.:|:.|||.:||..||:::..||.|.|.....:|..|...|:
Mouse    90 WLSGVLLTALGETGNFAAYGVAPITLIAPLGCMSVTGSAIISVIFLKENLRASDLLGMTLAFAGT 154

  Fly   159 TIIVIHSPKEKEIEDLQLLFDMLLDPVFILYVICIVGSTVFVAC---FIAPRHGHTNVVVYIFLC 220
            .::|..:|...:....:.:....:...|::|||.    .:.|.|   :...|.|..::||.:.|.
Mouse   155 YLLVNFAPNVTQAISARTVQYYFVGWQFLVYVIL----EILVFCILLYFHKRKGMKHIVVLLTLV 215

  Fly   221 SGIGSLTVMSCKALGLAIRQTLNNGGNVFLTWMPWFLILV-TVTFIAIQMNYLNKALDIFNTSIV 284
            :.:.||||:|.||:...|  ||:..|.:.||:..::::|| .:.....|:.:||:|.:::..:.|
Mouse   216 ALLASLTVISVKAVSGMI--TLSVTGKMQLTYAIFYIMLVIMIASCVFQVKFLNQATELYTMTTV 278

  Fly   285 TPVYYVMFTTLVIAASAILFKEFTHMRFDDILGDVCGFLIVITAVFLLNAFRDID------ISLN 343
            .||.:|.|||..|.|..|.::||....|..:...:.|..:....|||:...|:.:      :.|.
Mouse   279 VPVNHVFFTTSAIIAGIIFYQEFLGAAFLTVFIYLFGCFLSFLGVFLVTRNREKEHLQQSFVDLG 343

  Fly   344 DVRGLMRPKMQRVSQFDEEVLVTSNTKERRLSYGS 378
            |:.|         .|..::|...||    .||||:
Mouse   344 DIPG---------KQMLDKVQPDSN----GLSYGT 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spict	NP_001260421.1	Mg_trans_NIPA	43..338	CDD:398984	88/298 (30%)
Nipal2	NP_663444.2	EamA	45..332	CDD:474045	88/298 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	352..383		7/18 (39%)