Protein Alignment spict and NIPAL1

DIOPT Version :10

• Sequence 1: NP_001260421.1
• Gene: spict / 34681
• FlyBaseID: FBgn0032451
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_997213.1
• Gene: NIPAL1 / 152519
• HGNCID: 27194
• Length: 410
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 166/340 - (48%)
• Similarity: 232/340 - (68%)
• Gaps: 18/340 - (5%)

  Fly    14 QVTVGGMLPVEANQSPETAPLSMAETVSNT-DFYIGVGLAISSCFFIGSSFIIKKKALIRLSRYG 77
            |:....:|..:.|.|...  ||::..|.|. ..|:|:.||:||..|||||||:|||.|::|:..|
Human    38 QLLASPVLYTDLNYSINN--LSISANVENKYSLYVGLVLAVSSSIFIGSSFILKKKGLLQLASKG 100

  Fly    78 EVRASAGGFGYLREWIWWAGLLTMGVGEAANFAAYAFAPASLVTPLGALSVIISAVMASRFLNEK 142
            ..||..||..||:||:||.|||:||.||||||||||||||:||||||||||:|||:::|.||||.
Human   101 FTRAGQGGHSYLKEWLWWVGLLSMGAGEAANFAAYAFAPATLVTPLGALSVLISAILSSYFLNEH 165

  Fly   143 LNLLGKIGCFLCILGSTIIVIHSPKEKEIEDLQLLFDMLLDPVFILYVICIVGSTVFVACFIAPR 207
            ||:.|||||.|.|||||::|||:|:|:|:..|..:...|.||.||.:.:.|...::.:...:||:
Human   166 LNIHGKIGCILSILGSTVMVIHAPQEEEVTSLHEMEMKLRDPGFISFAVIITVISLVLILIVAPK 230

  Fly   208 HGHTNVVVYIFLCSGIGSLTVMSCKALGLAIRQTLNNGGNVFLTWMP-------WFLILVTVTFI 265
            .|.||::|||.:||.||:.:|.|.|.||:||::        .:.|.|       :.|:.|.|..:
Human   231 KGQTNILVYISICSLIGAFSVSSVKGLGIAIKE--------LIEWKPVYKHPLVFVLLAVLVLSV 287

  Fly   266 AIQMNYLNKALDIFNTSIVTPVYYVMFTTLVIAASAILFKEFTHMRFDDILGDVCGFLIVITAVF 330
            ..|:||||||||.||||:|||:|||.||::|:..|||||:|:..|...||:|.:.||..:|..:|
Human   288 TTQINYLNKALDTFNTSLVTPIYYVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIF 352

  Fly   331 LLNAFRDIDISLNDV 345
            ||:||::.||:.:::
Human   353 LLHAFKNTDITWSEL 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spict	NP_001260421.1	Mg_trans_NIPA	43..338	CDD:398984	156/302 (52%)
NIPAL1	NP_997213.1	EamA	66..358	CDD:474045	155/299 (52%)