Protein Alignment CG5776 and YTA6

DIOPT Version :10

• Sequence 1: NP_609585.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_015251.1
• Gene: YTA6 / 856031
• SGDID: S000005995
• Length: 754
• Species: Saccharomyces cerevisiae
• Alignment Length: 819
• Identity: 190/819 - (23%)
• Similarity: 326/819 - (39%)
• Gaps: 223/819 - (27%)

  Fly    74 KDLPTKYANMLVFVSEGAMQLAQLH-----IGQHVVLEAPSTAEQPLVRIVWPTSEQFLTTVFVS 133
            |:|.|    :||:|:||..::.:.:     :|..||       :.|.:|.:   .|.|
Yeast    53 KNLDT----LLVYVNEGLRKIEKTYTLKKGLGNLVV-------DHPELRSI---IEDF------- 96

  Fly   134 EGDFKLHCTQLRGKLLKISALHPSRLTAA--ASISLKHVNT-----TETSLKSVQLQDAIALLKR 191
                     |:.|:.::|:......|.|.  .|.||...::     |...|:..:|....:  ||
Yeast    97 ---------QILGQDIRIARRKAETLMAEGNGSPSLSSSSSVLGLGTGNGLRFPKLWRMGS--KR 150

  Fly   192 DMVNRVFYKDSLIHMNFFNKSLTFRLERWQSTVEEALAGLSLDSKPLQFIQVTNVTKLHLITDDA 256
            |.:.....|::.|     ||                              |..|:.:       |
Yeast   151 DKLKEADEKEAKI-----NK------------------------------QADNIRR-------A 173

  Fly   257 NQQEEEQKISHRITKCQIGGLDRQLQLVEESMEYALGFRTLPAGLRVSRGLLLYGATGCGKSMVL 321
            .:.|||:|:..::.      .:|.|:|..|.:          ..|:|.            :.:..
Yeast   174 RKLEEEKKLGAKLQ------YERDLELQREKL----------IELKVK------------EKVEF 210

  Fly   322 EAMCAVAEERSQGHVQLIRINSGEVYSKFLGETEQKLGAIF--ERAYNHYPHPTLLLIEDVHNLC 384
            |....:.||         |:...|...|...:.|:|..:..  ||..|:....:|..........
Yeast   211 EVAQKLEEE---------RVKREEEERKHREQAEKKRISTLKHERKTNYKSRASLDNFSSSSKSS 266

  Fly   385 PKQENSDLVKRVSLAFLSLLDQLSSPSQLKGSKTFVLATSSQI-------DTLHPSIRRAGRLDN 442
            .|.:|| |:||.||..:....:.......|..:...:..::|:       ...|..:...|...|
Yeast   267 GKIDNS-LIKRRSLDVVRTSGERVRTPVRKSMEAAEIGMAAQLAWSQYQNGANHSKVSNNGSHSN 330

  Fly   443 EVEL---GAPSSQARLE-----IVRCLIKSV----EHQLSDEEVEHVASITHGYVGADLAN---- 491
            |:::   ..|..:.|.:     :.|.:|||.    ::..|...:.     |:..:.|..:|
Yeast   331 ELQIRYKPTPPLKKRYDYKKPTVNRPIIKSPTLNRQNSKSSRNIP-----TNSKLKASKSNTNKV 390

  Fly   492 --------------LVYAAMLQAQPNPLQ-----------------------MPHLQAALTRIKP 519
                          ||.|..:.|:..|::                       :..:|........
Yeast   391 SRRNEQNLEPSSPVLVSATAVPAESKPMRSKSGTPDKESSASSSLDSRKEDILKSVQGVDRNACE 455

  Fly   520 SAMREVLIECPNVQWSDIGGQSELRLAMQQAIEWPLLHADKFQRLGIKPPRGILMFGPPGCSKTM 584
            ..:.|:|:....|.|.||.|....:.::::|:.:|.|..|.|:.|. :|.||:|:|||||..|||
Yeast   456 QILNEILVTDEKVYWEDIAGLRNAKNSLKEAVVYPFLRPDLFKGLR-EPVRGMLLFGPPGTGKTM 519

  Fly   585 IAKALATESKLNFLSIKGPELFSMWVGESERAVREVFRKARQVAPAIVFFDEIDAIGGERSEGDG 649
            ||||:||||...|.|:....|.|.::||||:.||.:|..|::::|:|:|.||||::...||:.:.
Yeast   520 IAKAVATESNSTFFSVSASSLLSKYLGESEKLVRALFYMAKKLSPSIIFIDEIDSMLTARSDNEN 584

  Fly   650 SSSGSSVKERVLTQLLTELDGVEAL------------QNVTIVAATNRPDMIDKALLRPGRIDRI 702
            .||     .|:.|:||.:...:.:.            ..|.::.|||.|..||.|..|  |..|.
Yeast   585 ESS-----RRIKTELLIQWSSLSSATAQSEDRNNTLDSRVLVLGATNLPWAIDDAARR--RFSRK 642

  Fly   703 LYVGLPQCEARREILKIKLRAMPISN--DVDMEKLVQLTEGYSGAEIQAVCHEAALRALEQ---- 761
            ||:.||..|.|...|| :|.|...::  |:|.|.:.::|||:||:::.::..|||:..:..
Yeast   643 LYIPLPDYETRLYHLK-RLMAKQKNSLQDLDYELITEMTEGFSGSDLTSLAKEAAMEPIRDLGDK 706

  Fly   762 ----SFE-AEDVKWTDFEHALKAVPPRTSPELLKLYEDY 795
                .|: ...::..||::||..:....|.|.|:.||::
Yeast   707 LMFADFDKIRGIEIKDFQNALLTIKKSVSSESLQKYEEW 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5776	NP_609585.1	CDC48	183..797	CDD:273521	164/698 (23%)
YTA6	NP_015251.1	PTZ00108	<158..412	CDD:240271	56/338 (17%)
		RecA-like_VPS4-like	473..645	CDD:410917	67/179 (37%)
		AAA_lid_3	670..714	CDD:465537	12/43 (28%)
		Vps4_C	<718..750	CDD:462762	9/28 (32%)