Protein Alignment CG5776 and CDC48

DIOPT Version :10

• Sequence 1: NP_609585.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_010157.1
• Gene: CDC48 / 851431
• SGDID: S000002284
• Length: 835
• Species: Saccharomyces cerevisiae
• Alignment Length: 821
• Identity: 250/821 - (30%)
• Similarity: 420/821 - (51%)
• Gaps: 117/821 - (14%)

  Fly    42 DDVGPDSEAEYVRSGAIYTRSLQQRNFEV-ESLKDLPTKYANMLVFVSEGAMQLAQLHIGQHVVL 105
            |..|.|...|...:.||..|..:.....| :::.|     .|.::.::...|...:|..|..|::
Yeast    10 DASGVDPREEDKTATAILRRKKKDNMLLVDDAIND-----DNSVIAINSNTMDKLELFRGDTVLV 69

  Fly   106 EAPSTAEQPLVRIVWPTSEQFLTTVFVSEGDFKLH---CTQLRGKLLKISALHPSRLTAAASISL 167
            :.....:..|:.::....|         :|..:::   ...||.:|..:..:||..       .:
Yeast    70 KGKKRKDTVLIVLIDDELE---------DGACRINRVVRNNLRIRLGDLVTIHPCP-------DI 118

  Fly   168 KHVNTTETSLKSVQLQDAIALLKRDMVNRVFYKDSLIH-MNFFNKSLTFRLERWQSTVEEALAGL 231
            |:.    |.:..:.:.|.|..:..::.: ||.|...:. .....|...|.:......||..:
Yeast   119 KYA----TRISVLPIADTIEGITGNLFD-VFLKPYFVEAYRPVRKGDHFVVRGGMRQVEFKV--- 175

  Fly   232 SLDSKPLQFIQVTNVTKLHLITDDANQQEEEQKISHRITKCQIGGLDRQLQLVEESMEYALG--- 293
             :|.:|.::..|...|.:|...:..|:::||..: :.:....|||..:|:..:.|.:|..|.
Yeast   176 -VDVEPEEYAVVAQDTIIHWEGEPINREDEENNM-NEVGYDDIGGCRKQMAQIREMVELPLRHPQ 238

  Fly   294 -FRTLPAGLRVSRGLLLYGATGCGKSMVLEAMCAVAEERSQGHVQLIRINSGEVYSKFLGETEQK 357
             |:.:  |::..||:|:||..|.||:::..   |||.|..   .....||..||.||..||:|..
Yeast   239 LFKAI--GIKPPRGVLMYGPPGTGKTLMAR---AVANETG---AFFFLINGPEVMSKMAGESESN 295

  Fly   358 LGAIFERAYNHYPHPTLLLIEDVHNLCPKQE--NSDLVKRVSLAFLSLLDQLSSPSQLKGSKTFV 420
            |...||.|..:  .|.::.|:::.::.||::  |.::.:||....|:|:|.:.:.|.:     .|
Yeast   296 LRKAFEEAEKN--APAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNV-----VV 353

  Fly   421 LATSSQIDTLHPSIRRAGRLDNEVELGAPSSQARLEIVRCLIKSVEHQLSDE-EVEHVASITHGY 484
            :|.:::.:::.|::||.||.|.||::|.|.:..|||::|...|::  :|:|: ::|.:|:.||||
Yeast   354 IAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNM--KLADDVDLEALAAETHGY 416

  Fly   485 VGADLANLVYAAMLQAQPNPLQ--------------------MPHLQAALTRIKPSAMREVLIEC 529
            ||||:|:|...|.:|.....:.                    |.:.:.||....|||:||.::|.
Yeast   417 VGADIASLCSEAAMQQIREKMDLIDLDEDEIDAEVLDSLGVTMDNFRFALGNSNPSALRETVVES 481

  Fly   530 PNVQWSDIGGQSELRLAMQQAIEWPLLHADKFQRLGIKPPRGILMFGPPGCSKTMIAKALATESK 594
            .||.|.|:||..|::..:::.:|:|:||.|::.:.|:.|.:|:|.:||||..||::|||:|||..
Yeast   482 VNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYGPPGTGKTLLAKAVATEVS 546

  Fly   595 LNFLSIKGPELFSMWVGESERAVREVFRKARQVAPAIVFFDEIDAIGGERSEGDGSSSGSSVKER 659
            .||:|:|||||.|||.||||..:|::|.|||..||.:||.||:|:|...|....|.:.|:|  :|
Yeast   547 ANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIAKARGGSLGDAGGAS--DR 609

  Fly   660 VLTQLLTELDGVEALQNVTIVAATNRPDMIDKALLRPGRIDRILYVGLPQCEARREILKIKLRAM 724
            |:.|||||:||:.|.:||.::.||||||.||.|:|||||:|:::||.||...||..||..:||..
Yeast   610 VVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQLRKT 674

  Fly   725 PISNDVDMEKLVQLTEGYSGAEIQAVCHEAALRALEQSFEA--------------EDVKWTD--- 772
            |:...:::..:.:.|:|:|||::..:...||..|::.|.||              |||:.||
Yeast   675 PLEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHEAEKEVKVEGEDVEMTDEGA 739

  Fly   773 ------------------FEHALKAVPPRTSPELLKLYEDY 795
                              |..|:|......|...|:.||.|
Yeast   740 KAEQEPEVDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAY 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5776	NP_609585.1	CDC48	183..797	CDD:273521	226/676 (33%)
CDC48	NP_010157.1	CDC48	48..785	CDD:273521	240/778 (31%)