Protein Alignment CG5776 and DRC11

DIOPT Version :10

• Sequence 1: NP_609585.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_001257514.1
• Gene: DRC11 / 79781
• HGNCID: 26195
• Length: 830
• Species: Homo sapiens
• Alignment Length: 728
• Identity: 131/728 - (17%)
• Similarity: 263/728 - (36%)
• Gaps: 183/728 - (25%)

  Fly    73 LKDLPTKYANMLVFVSEGAMQ-------LAQLHIGQHVVLEAPSTAEQ------PLVRI--VWPT 122
            :|.:|...|..|:.::|.|.|       :.|:::.::...::....::      ..:||  ||..
Human   163 VKSIPFDEAVKLIQIAERARQGRLRALFMKQIYLQEYRAKQSKMLGKKVTDTWAAALRIQKVWRR 227

  Fly   123 SEQFLTTVFVSEGDFKLHCTQLRGKLLKISALHPSRLTAAASISLKHVNTTETSLKSVQL----- 182
            ..|            :....:||.:.:....::|..|....|.::......:.....||:
Human   228 FHQ------------RKETEKLREEEMIFLGMNPPPLFNEVSATVIQAEKVDRLRNEVQIKHEED 280

  Fly   183 -QDAIALLKRD--MVNRVFYK----DSLIHMNFFNKSLTFRLERWQSTVEEALAGLSLDSKPLQF 240
             ::|:..:|.|  ::..|..|    |.:.|.....::||.....:.. |||..:.:....|.:|
Human   281 YREALVTIKNDLKLIEGVDIKENLQDQIRHWFIECRNLTGTFPDYPD-VEEGGSAIIFSDKTIQ- 343

  Fly   241 IQVTNVTKLHLITD-DANQQEEE---------QKISHRITKCQIGGLDRQLQLVEE-SMEYALGF 294
                     .:|.| .|||:|||         :|...:..|.:.|..::..:..|: .|..:|..
Human   344 ---------QVIEDIIANQEEEEKNKKKKKKKEKQPKKAKKQKKGTKEKNKEEDEKWKMSPSLFL 399

  Fly   295 RTLPAGLRVSRGLLLYGATGCGKSMVLEAMCAVAEERSQGHVQLIRINSGEVYSKFLGETEQKLG 359
            ..:..|....:.:.:........|...:......|:|.:...: |||...|:..:.|...:..:.
Human   400 PAMKEGCNAYKEIWMKKDESWNFSQDYDPELIKEEKRKELQSE-IRIQVDELMRQELKNLKLAVD 463

  Fly   360 AIFERAYNHYPHPTLLLIEDVHNLCPKQENSDLVKRVSLAFLSLLDQLSSPSQLKGSKTFVLATS 424
            ...||...                ..|:::....|:            ....:.|..|...|...
Human   464 RERERPVK----------------AGKKKDKKKGKK------------GKKKEKKAKKDKDLTAD 500

  Fly   425 SQIDTLHPSIRRAGRLDNEVELGAPSSQARLEIVRCLIKSVEHQLSDEEVEHVASITHGYVGADL 489
            ..|::|:..:         ||.|            .||::::..|||...|      :.|:|
Human   501 RTIESLYKEL---------VEEG------------LLIQALKVNLSDYIGE------YSYLG--- 535

  Fly   490 ANLVYAAMLQAQPNPLQMPHLQAALTRIKPSAMREVLIE-CPNVQWSDIGGQSELRLAMQQAIE- 552
                                          :.:|:|.|| .|::            |.::|.|.
Human   536 ------------------------------TTLRQVSIEPMPSL------------LDVRQLITL 558

  Fly   553 ---WPLLHADKFQRLGIKPP--RGILMFGPPGCSKTMIAKALATESKLNFLSIKGPELFSMWVGE 612
               |||..|...:    |.|  :.:|:.||.|..|.|:..|:.||:..|..::....:...:.|:
Human   559 YGIWPLGSAAVHE----KAPLVKSLLLAGPSGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGK 619

  Fly   613 S--ERAVREVFRKARQVAPAIVFFDEIDAIGGERSEGDGSSSGSSVKERVLTQLLTELDGVEALQ 675
            :  :..:..||:.|||:.|::|:.::.:....::.......:.....::.|.|:|..|   :...
Human   620 NGLQMMLHAVFKVARQLQPSVVWIEDTEKTFYKKVPNAEKMNEPKRLKKHLPQILKLL---KPDD 681

  Fly   676 NVTIVAATNRPDMIDKALLRPGRI-DRILYVGLPQCEARREILK--IKLRAMPISNDVDMEKLVQ 737
            .:.||..|.||  .|..|....:: .:|:.|..|...:|..:.|  |:.....:::.:::..|.:
Human   682 RILIVGTTRRP--FDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAK 744

  Fly   738 LTEGYSGAEIQAV 750
            :|:|::...|..|
Human   745 VTDGFTQGHIVEV 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5776	NP_609585.1	CDC48	183..797	CDD:273521	111/597 (19%)
DRC11	NP_001257514.1	RecA-like_IQCA1	551..710	CDD:410914	38/167 (23%)